Cited by 301Renal function and acid-base balanceClinical Laboratory Practices and Quality ControlOcean Acidification Effects and Responses

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Physiological Approach to Assessment of Acid–Base Disturbances

Berend, Kenrick, de Vries, Aiko P.J., Gans, Rijk O.B.·2014·New England Journal of Medicine

DOI 10.1056/nejmra1003327

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Abstract

Acid–base homeostasis is fundamental for maintaining life. This article reviews a stepwise method for the physiological approach to evaluation of acid–base status.

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Crossref · 10.1056/nejmra1003327

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Textbook of Medical Physiology
Guyton, A. C., & Hall, J. E. (1966) · Annals of Internal Medicine · doi:10.7326/0003-4819-64-6-1363_2 · Cited by 9,760
Textbook of Medical Physiology 11th ed.
Guyton, A. C., & Hall, J. E. (2006) · Cited by 490
Renal Tubular Acidosis
Soriano, J. R. (2002) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000023430.92674.e5 · Cited by 481
Serum Anion Gap
Kraut, J. A., & Madias, N. E. (2006) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03020906 · Cited by 433
Toxic Alcohol Ingestions
Kraut, J. A., & Kurtz, I. (2007) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03220807 · Cited by 401
Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients
Gunnerson, K. J., Saul, M. I., He, S. X., & Kellum, J. A. (2006) · Critical Care · doi:10.1186/cc3987 · Cited by 397
Chloride: The queen of electrolytes?
Berend, K., van Hulsteijn, L. H., & Gans, R. O. B. (2011) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2011.11.013 · Cited by 329
Self-citation
Simple and Mixed Acid-Base Disorders
Narins, R. G., & Emmett, M. (1980) · Medicine · doi:10.1097/00005792-198005000-00001 · Cited by 307
THE THEORY OF NEUTRALITY REGULATION IN THE ANIMAL ORGANISM
Henderson, L. J. (1908) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1908.21.4.427 · Cited by 254
Metabolic acidosis in patients with severe sepsis and septic shock: A longitudinal quantitative study
Noritomi, D. T., Soriano, F. G., Kellum, J. A., Cappi, S. B., Biselli, P., Libório, A. B., & Park, M. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181a59165 · Cited by 230

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Hasselbalch KA, 1916, Biochem Z, 78, 112
Ghosh AK, 2006, J Assoc Physicians India, 54, 720
Rowe KJ, 2007, Surgery, 25, 375
Hassan H, 2004, Mt Sinai J Med, 71, 281
Adrogue HJ, 2006, J Nephrol, 19, S97

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Authors: Berend, K., de Vries, A. P. J., & Gans, R. O. B.
Affiliations: St. Elisabeth Hospital (CW)
University Medical Center Groningen (NL)
ORCID: Berend, Kenrick
Gans, Rijk O.B.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2014-10-09
Volume: 371
Issue: 15
Pages: 1434-1445
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra1003327
OpenAlex: W2154779047
Cited by: 301
References: 91
Citations by year: 2026: 37 · 2025: 35 · 2024: 21 · 2023: 26 · 2022: 22 · 2021: 21 · 2020: 22 · 2019: 23 · 2018: 14 · 2017: 27 · 2016: 25 · 2015: 25 · 2014: 3
FWCI: 3.87
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Leiden Repository (Leiden University) (submittedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Topics: Health Sciences › Medicine › Nephrology › Renal function and acid-base balance
Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
Physical Sciences › Earth and Planetary Sciences › Oceanography › Ocean Acidification Effects and Responses
Keywords: acid-base disorders, acid-base balance, acid-base status assessment, physiological assessment, acidosis, alkalosis
MeSH terms: Acid-Base Imbalance, Bicarbonates, Homeostasis, Humans, Hydrogen-Ion Concentration, Oxygen, Reference Values

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Physiological Approach to Assessment of Acid–Base Disturbances

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