Idiopathic Pulmonary Fibrosis

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

Raghu, G., Collard, H. R., Egan, J. J., Martinez, F. J., Behr, J., Brown, K. K., Colby, T. V., Cordier, J.-F., Flaherty, K. R., Lasky, J. A., et al. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2009-040gl · Cited by 7,186

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

Richeldi, L., du Bois, R. M., Raghu, G., Azuma, A., Brown, K. K., Costabel, U., Cottin, V., Flaherty, K. R., Hansell, D. M., Inoue, Y., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402584 · Cited by 4,654

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

King, T. E., Bradford, W. Z., Castro-Bernardini, S., Fagan, E. A., Glaspole, I., Glassberg, M. K., Gorina, E., Hopkins, P. M., Kardatzke, D., Lancaster, L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402582 · Cited by 3,975

Screening for Lung Cancer: U.S. Preventive Services Task Force Recommendation Statement

Moyer, V. A., & on behalf of the U.S. Preventive Services Task Force* (2013) · Annals of Internal Medicine · doi:10.7326/m13-2771 · Cited by 2,642

Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017.

MacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N. C., Mayo, J. R., Mehta, A. C., Ohno, Y., Powell, C. A., Prokop, M., et al. (2017) · Radiology · doi:10.1148/radiol.2017161659 · Cited by 2,491

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis: An Update of the 2011 Clinical Practice Guideline

Raghu, G., Rochwerg, B., Zhang, Y., Garcia, C. A. C., Azuma, A., Behr, J., Brozek, J. L., Collard, H. R., Cunningham, W., Homma, S., et al. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201506-1063st · Cited by 1,916

Prednisone, Azathioprine, and N -Acetylcysteine for Pulmonary Fibrosis

The Idiopathic Pulmonary Fibrosis Clinical Research Network (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1113354 · Cited by 1,654

Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report

Collard, H. R., Ryerson, C. J., Corte, T. J., Jenkins, G., Kondoh, Y., Lederer, D. J., Lee, J. S., Maher, T. M., Wells, A. U., Antoniou, K. M., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0801ci · Cited by 1,444

Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis

Armanios, M. Y., Chen, J. J.-L., Cogan, J. D., Alder, J. K., Ingersoll, R. G., Markin, C., Lawson, W. E., Xie, M., Vulto, I., Phillips, J. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa066157 · Cited by 1,357

A consensus document for the selection of lung transplant candidates: 2014–an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation

Weill, D., Benden, C., Corris, P. A., Dark, J. H., Davis, R. D., Keshavjee, S., Lederer, D. J., Mulligan, M. J., Patterson, G. A., Singer, L. G., et al. (2015) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2014.06.014 · Cited by 1,329

Alveolar Epithelial Type 2 Cell Dysfunction in Idiopathic Pulmonary Fibrosis

Zhu, W., Tan, C., & Zhang, J. (2022) · Lung · doi:10.1007/s00408-022-00571-w · Cited by 50

Aspirin alleviates pulmonary fibrosis through PI3K/AKT/mTOR-mediated autophagy pathway

Peng, J., Xiao, X., Li, S., Lyu, X., Gong, H., Tan, S., Dong, L., Sanders, Y. Y., & Zhang, X. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112085 · Cited by 48

The Role of Occupational and Environmental Exposures in the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Narrative Literature Review

Trethewey, S. P., & Walters, G. I. (2018) · Medicina · doi:10.3390/medicina54060108 · Cited by 49

IL-25 contributes to lung fibrosis by directly acting on alveolar epithelial cells and fibroblasts

Xu, X., Luo, S., Li, B., Dai, H., & Zhang, J. (2019) · Experimental Biology and Medicine · doi:10.1177/1535370219843827 · Cited by 45

Air Pollution—An Overlooked Risk Factor for Idiopathic Pulmonary Fibrosis

Majewski, S., & Piotrowski, W. J. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm10010077 · Cited by 48

VEGFR1-tyrosine kinase signaling in pulmonary fibrosis

Amano, H., Matsui, Y., Hatanaka, K., Hosono, K., & Ito, Y. (2021) · Inflammation and Regeneration · doi:10.1186/s41232-021-00166-7 · Cited by 49

Notch3 Deficiency Attenuates Pulmonary Fibrosis and Impedes Lung-Function Decline

Vera, L., García‐Olloqui, P., Petri, E., Viñado, A. C., Valera, P. S., Blasco‐Iturri, Z., Calvo, I. A., Cenzano, I., Ruppert, C., Zulueta, J. J., et al. (2021) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2020-0516oc · Cited by 44

Genetic, social, and environmental risk factors in rheumatoid arthritis-associated interstitial lung disease

Wheeler, A. M., Baker, J. F., Poole, J. A., Ascherman, D. P., Yang, Y., Kerr, G. S., Reimold, A. M., Kunkel, G. A., Cannon, G. W., Wysham, K. D., et al. (2022) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2022.152098 · Cited by 44

Design and rationale for the prospective treatment efficacy in IPF using genotype for NAC selection (PRECISIONS) clinical trial

Podolanczuk, A. J., Kim, J. S., Cooper, C. B., Lasky, J. A., Murray, S., Oldham, J. M., Raghu, G., Flaherty, K. R., Spino, C., Noth, I., et al. (2022) · BMC Pulmonary Medicine · doi:10.1186/s12890-022-02281-8 · Cited by 46

Cellular and Molecular Mechanisms in Idiopathic Pulmonary Fibrosis

Zhang, Y., & Wang, J. (2023) · Advances in respiratory medicine · doi:10.3390/arm91010005 · Cited by 47

Biomarkers in idiopathic pulmonary fibrosis: Current insight and future direction

Zheng, Z., Peng, F., & Zhou, Y. (2024) · Chinese Medical Journal - Pulmonary and Critical Care Medicine · doi:10.1016/j.pccm.2024.04.003 · Cited by 49

Antineutrophil Cytoplasmic Antibody–Associated Lung Fibrosis

Borie, R., & Crestani, B. (2018) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0038-1669914 · Cited by 44

Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease

Elko, E. A., Cunniff, B., Seward, D. J., Chia, S. B., Aboushousha, R., van de Wetering, C., van der Velden, J. L. J., Manuel, A. M., Shukla, A., Heintz, N. H., et al. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7752 · Cited by 44

Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin

Zhang, C., Cai, R., Lazerson, A., Delcroix, G. J.-R., Wangpaichitr, M., Mirsaeidi, M. S., Griswold, A. J., Schally, A. V., & Jackson, R. M. (2019) · Lung · doi:10.1007/s00408-019-00257-w · Cited by 44

A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis

Keum, H., Kim, D. H., Kim, J., Kim, T. W., Whang, C., Jung, W., & Jon, S. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120986 · Cited by 44

Evaluation for clinical benefit of metformin in patients with idiopathic pulmonary fibrosis and type 2 diabetes mellitus: a national claims-based cohort analysis

Teague, T., Payne, S. R., Kelly, B. T., Dempsey, T. M., McCoy, R. G., Sangaralingham, L. R., & LIMPER, A. H. (2022) · Respiratory Research · doi:10.1186/s12931-022-02001-0 · Cited by 50

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation

Ballester, B., Milara, J., & Cortijo, J. (2020) · Oncotarget · doi:10.18632/oncotarget.27526 · Cited by 43

Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection

Huang, S., Goplen, N. P., Zhu, B., Cheon, I. S., Son, Y. M., Wang, Z., Li, C., Dai, Q., Jiang, L., Xiang, M., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223430 · Cited by 42

Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF): an overview of current and future therapeutic strategies

Biondini, D., Balestro, E., Sverzellati, N., Cocconcelli, E., Bernardinello, N., Ryerson, C. J., & Spagnolo, P. (2020) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2020.1724096 · Cited by 44

Active mTOR in Lung Epithelium Promotes Epithelial–Mesenchymal Transition and Enhances Lung Fibrosis

Saito, M., Mitani, A., Ishimori, T., Miyashita, N., Isago, H., Mikami, Y., Noguchi, S. F., Tarui, M., & Nagase, T. (2020) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2019-0255oc · Cited by 43

Snail-mediated partial epithelial mesenchymal transition augments the differentiation of local lung myofibroblast

Wang, Y., Li, S., Zhao, J., Li, Q., Xu, C., Wu, H., Zhu, Z., & Tian, L. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.128870 · Cited by 43

The Diagnosis and Treatment of Pulmonary Fibrosis

Kreuter, M., Müller-Ladner, U., Costabel, U., Jonigk, D. D., & Heußel, C. P. (2021) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.m2021.0018 · Cited by 46

Evodiamine alleviates lipopolysaccharide‐induced pulmonary inflammation and fibrosis by activating apelin pathway

Ye, C., Zhang, N., Zhao, Q., Xie, X., Li, X., Zhu, H., Peng, C. Y., Huang, W., & Han, B. (2021) · Phytotherapy Research · doi:10.1002/ptr.7062 · Cited by 43

Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model

Bluhmki, T., Traub, S., Müller, A.-K., Groetzner, S., Schruf, E., Bammert, M., Leist, M., Gantner, F., Garnett, J. P., & Heilker, R. (2021) · Scientific Reports · doi:10.1038/s41598-021-96565-4 · Cited by 44

Mapping the metabolomic and lipidomic changes in the bleomycin model of pulmonary fibrosis in young and aged mice

Weckerle, J., Picart‐Armada, S., Klee, S., Bretschneider, T., Luippold, A. H., Rist, W., Haslinger, C., Schlüter, H., Thomas, M. J., Krawczyk, B., et al. (2021) · Disease Models & Mechanisms · doi:10.1242/dmm.049105 · Cited by 43

CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial

Popmihajlov, Z., Sutherland, D., Horan, G. S. B., Ghosh, A., Lynch, D. A., Noble, P. W., Richeldi, L., Reiss, T. F., & Greenberg, S. (2022) · BMJ Open Respiratory Research · doi:10.1136/bmjresp-2021-001060 · Cited by 44

COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis

Sinha, S., Castillo, V., Espinoza, C. R., Tindle, C., Fonseca, A. G., Dan, J. M., Katkar, G. D., Das, S., Sahoo, D., & Ghosh, P. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104185 · Cited by 46

Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF)

Richeldi, L., Azuma, A., Cottin, V., Kreuter, M., Maher, T. M., Martínez, F. J., Oldham, J. M., Valenzuela, C., Gordat, M., Liu, Y., et al. (2023) · BMJ Open Respiratory Research · doi:10.1136/bmjresp-2022-001563 · Cited by 44

Interleukin-8 release by endothelial colony-forming cells isolated from idiopathic pulmonary fibrosis patients might contribute to their pathogenicity

Blandinières, A., Gendron, N., Bacha, N. C., Bièche, I., Chocron, R., Nunès, H., Névo, N., Rossi, E., Crestani, B., Lecourt, S., et al. (2019) · Angiogenesis · doi:10.1007/s10456-018-09659-5 · Cited by 44

Safety, Pharmacokinetics, and Pharmacodynamics of the Autotaxin Inhibitor GLPG1690 in Healthy Subjects: Phase 1 Randomized Trials

van der Aar, E., Desrivot, J., Dupont, S., Heckmann, B., Fieuw, A. M., Stutvoet, S., Fagard, L., de Wal, K. V., & Helmer, E. (2019) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.1424 · Cited by 42

Nicorandil ameliorates bleomycin-induced pulmonary fibrosis in rats through modulating eNOS, iNOS, TXNIP and HIF-1α levels

Kseibati, M. O., Shehatou, G. S. G., Sharawy, M. H., Eladl, A. E., & Salem, H. A. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117423 · Cited by 42

State-of-the-Art of Nanodiagnostics and Nanotherapeutics against SARS-CoV-2

Derakhshan, M. A., Amani, A., & Majidi, R. F. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c22381 · Cited by 42

Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis

Kasuya, Y., Kim, J., Hatano, M., Tatsumi, K., & Matsuda, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116041 · Cited by 40

GANE can Improve Lung Fibrosis by Reducing Inflammation via Promoting p38MAPK/TGF-β1/NF-κB Signaling Pathway Downregulation

Mohamad, E. A., Mohamed, Z. N., Hussein, M. A., & Elneklawi, M. S. (2022) · ACS Omega · doi:10.1021/acsomega.1c06591 · Cited by 42

PCSK6 and Survival in Idiopathic Pulmonary Fibrosis

Oldham, J. M., Allen, R. J., Lorenzo-Salazar, J. M., Molyneaux, P. L., Ma, S., Joseph, C., Kim, J. S., Guillén‐Guío, B., Hernández-Beeftink, T., Kropski, J. A., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202205-0845oc · Cited by 42

Delivery of Stem Cell Secretome for Therapeutic Applications

Li, F., Zhang, J., Yi, K., Wang, H., Wei, H., Chan, H. F., Tao, Y., & Li, M. (2022) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c01312 · Cited by 42

Changes in serum metabolomics in idiopathic pulmonary fibrosis and effect of approved antifibrotic medication

Seeliger, B., Carleo, A., Wendel‐Garcia, P. D., Fuge, J., Montes‐Worboys, A., Schuchardt, S., Molina‐Molina, M., & Prasse, A. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.837680 · Cited by 43

Serum Proteomics Identifies Biomarkers Associated With the Pathogenesis of Idiopathic Pulmonary Fibrosis

Wang, L., Zhu, M., Li, Y., Yan, P., Li, Z., Chen, X., Yang, J., Pan, X., Zhao, H., Wang, S., et al. (2023) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2023.100524 · Cited by 41

PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo

Sun, H., Ren, C., Lee, D. H., Wang, W., Guo, X., Hao, Y., Wang, X., Zhang, H., Xiao, W.-Q., Li, N., et al. (2023) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-023-00460-x · Cited by 41

Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.

Feng, F., Wang, Z.-C., Li, R., Wu, Q., Gu, C., Xu, Y., Peng, W.-P., Han, D., Zhou, X.-M., Wu, J., et al. (2019) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2019.108669 · Cited by 38

CD44 inhibits α-SMA gene expression via a novel G-actin/MRTF-mediated pathway that intersects with TGFβR/p38MAPK signaling in murine skin fibroblasts

Wang, Y., Mack, J. A., & Maytin, E. V. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.007834 · Cited by 41

Co-delivery of siPTPN13 and siNOX4 via (myo)fibroblast-targeting polymeric micelles for idiopathic pulmonary fibrosis therapy

Hou, J., Ji, Q., Ji, J., Ju, S., Xu, C., Yong, X., Xu, X., Muddassir, M., Chen, X., Xie, J., et al. (2021) · Theranostics · doi:10.7150/thno.54217 · Cited by 45

Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin/Islr in Cancer Fibrosis

Takahashi, M., Kobayashi, H., Mizutani, Y., Hara, A., Iida, T., Miyai, Y., Asai, N., & Enomoto, A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.749924 · Cited by 43

Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts

Dubey, S., Dubey, P. K., Umeshappa, C. S., Ghebre, Y. T., & Krishnamurthy, P. (2022) · Journal of Cellular Physiology · doi:10.1002/jcp.30684 · Cited by 41

Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation

Jyothula, S., Peters, A. M., Liang, Y., Bi, W., Shivshankar, P., Yau, S., Garcha, P., Yuan, X., Akkanti, B. H., Collum, S. D., et al. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104351 · Cited by 40

Stromal–immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult

Worrell, J. C., & MacLeod, M. K. L. (2021) · Immunology · doi:10.1111/imm.13319 · Cited by 42

Sex and Gender in Lung Disease and Sleep Disorders

Sodhi, A., Pisani, M. A., Glassberg, M. K., Bourjeily, G. R., & D’Ambrosio, C. M. (2022) · CHEST Journal · doi:10.1016/j.chest.2022.03.006 · Cited by 41

ACSS3 regulates the metabolic homeostasis of epithelial cells and alleviates pulmonary fibrosis

Wang, L., Yuan, H., Li, W., Yan, P., Zhao, M., Li, Z., Zhao, H., Wang, S., Wan, R., Li, Y., et al. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166960 · Cited by 40

Curcumin analogue EF24 prevents alveolar epithelial cell senescence to ameliorate idiopathic pulmonary fibrosis via activation of PTEN

Zhang, Y., Liu, J., Zheng, R., Hou, K., Zhang, Y., Jia, T., Lu, X., Samarawickrama, P. N., Jia, S., He, Y., et al. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155882 · Cited by 43

From senescence to scarring: Exploring TGF-β signaling in cellular aging, fibrotic remodeling, and pulmonary fibrosis

Bhardwaj, S., Gautam, R. K., & Kushwaha, S. (2025) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2025.08.003 · Cited by 50

Clinical features and long-term outcomes of interstitial lung disease with anti-neutrophil cytoplasmic antibody

Sun, X., Peng, M., Zhang, T., Li, Z., Song, L., Li, M., & Shi, J. (2021) · BMC Pulmonary Medicine · doi:10.1186/s12890-021-01451-4 · Cited by 40

The Role of Hippo/YAP Signaling in Alveolar Repair and Pulmonary Fibrosis

Gokey, J. J., Patel, S. D., & Kropski, J. A. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.752316 · Cited by 40

Mendelian randomisation highlights hypothyroidism as a causal determinant of idiopathic pulmonary fibrosis

Zhang, Y., Zhao, M., Guo, P., Wang, Y., Liu, L., Zhao, J., Gao, L., Yuan, Z., Xue, F., & Zhao, J. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103669 · Cited by 40

Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells

Moreira, A., Müller, M., Costa, P. F., & Kohl, Y. (2021) · Advanced Biology · doi:10.1002/adbi.202101139 · Cited by 49

Advances in ameliorating inflammatory diseases and cancers by andrographolide: Pharmacokinetics, pharmacodynamics, and perspective

Qu, J., Liu, Q., You, G., Ye, L., Jin, Y., Kong, L., Guo, W., Xu, Q., & Sun, Y. (2021) · Medicinal Research Reviews · doi:10.1002/med.21873 · Cited by 40

Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

Aversa, Z., Atkinson, E. J., Carmona, E. M., White, T. A., Heeren, A. A., Jachim, S. K., Zhang, X., Cummings, S. R., Chiarella, S. E., LIMPER, A. H., et al. (2023) · Respiratory Research · doi:10.1186/s12931-023-02403-8 · Cited by 41

Protective effect of dimethyl itaconate against fibroblast–myofibroblast differentiation during pulmonary fibrosis by inhibiting TXNIP

Han, Y., Gu, X., Yang, C., Ji, H.-M., Lan, Y., Bi, Y., Si, R., Qu, J., Cheng, M.-H., & Gao, J. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30456 · Cited by 39

Efficacy and safety of N‑acetylcysteine therapy for idiopathic pulmonary fibrosis: An updated systematic review and meta‑analysis

Fen, F., Zhang, J., Wang, Z., Wu, Q., & Zhou, X. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7579 · Cited by 39

Epidemiology of idiopathic pulmonary fibrosis: a population-based study in primary care

Harari, S. A., Davì, M., Biffi, A., Caminati, A., Ghirardini, A., Lovato, V., Cricelli, C. A., & Lapi, F. (2019) · Internal and Emergency Medicine · doi:10.1007/s11739-019-02195-0 · Cited by 42

P2 Purinergic Signaling in the Distal Lung in Health and Disease

Wirsching, E., Fauler, M., Fois, G., & Frick, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21144973 · Cited by 42

Deep Learning of Computed Tomography Virtual Wedge Resection for Prediction of Histologic Usual Interstitial Pneumonitis

Shaish, H. A., Ahmed, F. S., Lederer, D. J., D’Souza, B. M., Armenta, P. M., Salvatore, M. M., Saqi, A., Huang, S., Jambawalikar, S., & Mutasa, S. (2020) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202001-068oc · Cited by 39

Overcoming interferon (IFN)-γ resistance ameliorates transforming growth factor (TGF)-β-mediated lung fibroblast-to-myofibroblast transition and bleomycin-induced pulmonary fibrosis

Chang, C., Lin, C., Lee, C., Chuang, H., Shih, F.-C., Wan, S.-W., Tai, C., & Chen, C. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114356 · Cited by 40

Antifibrotic effect of Gancao Ganjiang decoction is mediated by PD-1 / TGF-β1 / IL-17A pathway in bleomycin-induced idiopathic pulmonary fibrosis

Wang, D., Gong, L., Li, Z., Chen, H., Xu, M., Rong, R., Zhang, Y., & Zhu, Q. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114522 · Cited by 39

Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis

Mou, Y., Wu, G., Wang, Q., Pan, T. S., Zhang, L., Xu, Y., Xiong, W., Zhou, Q., & Wang, Y. (2021) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10280 · Cited by 38

Alveolar epithelial regeneration in the aging lung

Han, S., Budinger, G. R. S., & Gottardi, C. J. (2023) · Journal of Clinical Investigation · doi:10.1172/jci170504 · Cited by 40

The gut-lung axis: the impact of the gut mycobiome on pulmonary diseases and infections

Sey, E. A., & Warris, A. (2024) · Oxford Open Immunology · doi:10.1093/oxfimm/iqae008 · Cited by 39

The evolving role of the lung microbiome in pulmonary fibrosis

Lipinski, J. H., Moore, B. B., & O’Dwyer, D. N. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00258.2020 · Cited by 40

DNA repair enzyme OGG1 promotes alveolar progenitor cell renewal and relieves PM2.5-induced lung injury and fibrosis

Yang, L., Liu, G., Fu, L., Zhong, W., Li, X., & Pan, Q. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111283 · Cited by 38

Idiopathic pulmonary fibrosis: Current knowledge, future perspectives and its importance in radiation oncology

Türkkan, G., Willems, Y. C. P., Hendriks, L. E. L., Mostard, R. L. M., Conemans, L. H., Gietema, H. A., Mitea, C., Peeters, S., & Ruysscher, D. D. (2020) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2020.11.020 · Cited by 36

Gene therapy strategies for idiopathic pulmonary fibrosis: recent advances, current challenges, and future directions

Ruigrok, M. J. R., Frijlink, H. W., Melgert, B. N., Olinga, P., & Hinrichs, W. L. J. (2021) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2021.01.003 · Cited by 41

Renin angiotensin aldosterone system in pulmonary fibrosis: Pathogenesis to therapeutic possibilities

Gupta, D., Kumar, A., Mandloi, A. S., & Shenoy, V. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105924 · Cited by 39

Peripheral blood circular RNA hsa_circ_0058493 as a potential novel biomarker for silicosis and idiopathic pulmonary fibrosis

Cheng, Z., Zhang, Y., Wu, S., Zhao, R., Yu, Y., Zhou, Y., Zhou, Z., Yang, D., Qiu, A., Xu, H., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113451 · Cited by 38

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Inhibitors of the Autotaxin-Lysophosphatidic Acid Axis and Their Potential in the Treatment of Interstitial Lung Disease: Current Perspectives

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Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis

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The Role of Interaction between Mitochondria and the Extracellular Matrix in the Development of Idiopathic Pulmonary Fibrosis

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The Role of Zinc in the Pathogenesis of Lung Disease

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Epidemiology and real-life experience in progressive pulmonary fibrosis

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Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis

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Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis

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Increased Airway Wall Thickness in Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis

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Particulate Matter Increases the Severity of Bleomycin-Induced Pulmonary Fibrosis through KC-Mediated Neutrophil Chemotaxis

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Multi-scale models of lung fibrosis

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The contribution of animal models to understanding the role of the immune system in human idiopathic pulmonary fibrosis

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Metabolic reprogramming: A driver of cigarette smoke-induced inflammatory lung diseases

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The role of viral and bacterial infections in the pathogenesis of IPF: a systematic review and meta-analysis

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Role of Ferroptosis in Fibrotic Diseases

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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis

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Pathogenic mechanisms and latest therapeutic approaches for radiation-induced lung injury: A narrative review

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