Cited by 2,056Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseasesTransplantation: Methods and Outcomes

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Idiopathic Pulmonary Fibrosis

Lederer, David J., Martinez, Fernando J.·2018·New England Journal of Medicine

DOI 10.1056/nejmra1705751

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Abstract

Idiopathic pulmonary fibrosis appears to be increasing in incidence. It requires early recognition and intervention with supportive care and pharmacologic agents to forestall its progression. Lung transplantation may be curative.

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Crossref · 10.1056/nejmra1705751

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Philp CJ, Siebeke I, Clements D, et al. ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis. Am J Respir Cell Mol Biol 2017 October 20 (Epub ahead of print).29053339
Parker J, Sawtell R, Gagnon L, et al. PBI-4050 is safe and well tolerated and shows evidence of benefit in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2017;195:A7606-A7606. abstract.

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Li, Y., Wu, Q., Sun, X., Shen, J., & Chen, H. (2020) · Stem Cells International · doi:10.1155/2020/5847876 · Cited by 66
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Ramani, K., & Biswas, P. S. (2019) · Cytokine · doi:10.1016/j.cyto.2018.11.003 · Cited by 68
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Hou, J., Ji, J., Chen, X., Cao, H., Tan, Y., Cui, Y., Xiang, Z., & Han, X. (2020) · FEBS Journal · doi:10.1111/febs.15669 · Cited by 66
Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
Jessen, H., Hoyer, N., Prior, T. S., Frederiksen, P., Karsdal, M. A., Leeming, D. J., Bendstrup, E. M., Sand, J. M. B., & Shaker, S. B. (2021) · Respiratory Research · doi:10.1186/s12931-021-01801-0 · Cited by 75
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Effendi, W. I., & Nagano, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010171 · Cited by 59
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Behr, J., Kolb, M. R. J., Song, J. W., Luppi, F., Schinzel, B., Stowasser, S., Quaresma, M., & Martínez, F. J. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201903-0488oc · Cited by 63
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Nosal, C. R., Ehlers, A., & Haspel, J. A. (2019) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021119-034602 · Cited by 70
Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis
Gajjala, P. R., Kasam, R. K., Soundararajan, D., Sinner, D. I., Huang, S. K., Jegga, A. G., & Madala, S. K. (2021) · JCI Insight · doi:10.1172/jci.insight.152503 · Cited by 65
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Zhang, J., Li, Y., Wan, J., Zhang, M., Li, C., & Lin, J. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154259 · Cited by 64
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Moll, M. R., Peljto, A. L., Kim, J. S., Xu, H., Debban, C. L., Chen, X., Menon, A. A., Putman, R. K., Ghosh, A., Saferali, A., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202212-2257oc · Cited by 63
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Authors: Lederer, D. J., & Martinez, F. J.
Affiliations: Columbia University Irving Medical Center (US)
From the Departments of Medicine and Epidemiology, Columbia University Irving Medical Center (D.J.L.), and the Department of Medicine, Weill Cornell Medical Center (F.J.M.) — both in New York.
ORCID: Lederer, David J.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2018-05-10
Volume: 378
Issue: 19
Pages: 1811-1823
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra1705751
OpenAlex: W2799479598
Cited by: 2,056
References: 98
Citations by year: 2026: 248 · 2025: 267 · 2024: 299 · 2023: 308 · 2022: 301 · 2021: 266 · 2020: 197 · 2019: 129 · 2018: 40
FWCI: 28.43
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Occupational and environmental lung diseases
Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
Keywords: idiopathic pulmonary fibrosis, incidence, early recognition, supportive care, pharmacotherapy, disease progression, lung transplantation
MeSH terms: Diagnosis, Differential, Dyspnea, Enzyme Inhibitors, Humans, Indoles, Lung, Oxygen Inhalation Therapy, Prognosis, Pyridones, Risk Factors, Tomography, X-Ray Computed, Transforming Growth Factor beta, Idiopathic Pulmonary Fibrosis

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