The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Life extension in Drosophila by feeding a drug
Open accessAbstract
We report that feeding Drosophila throughout adulthood with 4-phenylbutyrate (PBA) can significantly increase lifespan, without diminution of locomotor vigor, resistance to stress, or reproductive ability. Treatment for a limited period, either early or late in adult life, is also effective. Flies fed PBA show a global increase in histone acetylation as well as a dramatically altered pattern of gene expression, including induction or repression of numerous genes. The delay in aging may result from the altered physiological state.
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Cites
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Cited by
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
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Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
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Ketone bodies as signaling metabolites
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The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers
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Metadata
- Authors
- Kang, H.-L., Benzer, S., & Min, K.-T.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2002-01-15
- Volume
- 99
- Issue
- 2
- Pages
- 838-843
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2078377781
- Cited by
- 295
- References
- 38
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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