Cited by 130Genomics and Chromatin DynamicsNuclear Structure and FunctionEpigenetics and DNA Methylation

The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.

Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing

Open access

Huang, Shengbing, Zhou, Hui, Katzmann, David, Hochstrasser, Mark, Atanasova, Elena, Zhang, Zhiguo·2005·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.0506176102PMC PMC1224646

Open this paper in CoChat — free account

Abstract

Epigenetic inheritance of heterochromatin structure is an important cellular process whose mechanism remains elusive. In this article, we describe the identification of nine enhancers of the silencing defect of a Saccharomyces cerevisiae -PCNA mutant by screening a library of ≈4,700 viable yeast deletion mutants. Of the nine mutants identified, six ( hir1 , hir3 , sas2 , sas4 , sas5 , and sir1 ) were previously known to reduce silencing synergistically with a mutation in Cac1p, the large subunit of chromatin assembly factor 1 (CAF-1). The predicted gene products that are affected in three other mutants ( nam7 , msh2 , and rtt106 ) have not been implicated previously in silencing. Characterization of the rtt106 Δ allele revealed that it synergistically reduced heterochromatin silencing when combined with a mutation in Cac1p but not with a mutation in Asf1p (a histone H3 and H4 chaperone). Moreover, Rtt106p interacted with histones H3 and H4 both in vitro and in vivo , and it displayed a nucleosome assembly activity in vitro . Furthermore, Rtt106p interacts with CAF-1 physically through Cac1p. These biochemical and genetic data indicate that Rtt106p is a previously uncharacterized histone chaperone connecting S phase to epigenetic inheritance.

Integrity signals

Registry

Crossref · 10.1073/pnas.0506176102

Cites

64 of 64 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization
Spellman, P. T., Sherlock, G. J., Zhang, M. Q., Iyer, V. R., Anders, K. R., Eisen, M. B., Brown, P. O., Botstein, D., & Futcher, B. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.12.3273 · Cited by 4,724
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
Tong, A. H. Y., Evangelista, M., Parsons, A. B., Xu, H., Bader, G. D., Pagé, N., Robinson, M., Raghibizadeh, S., Hogue, C. W. V., Bussey, H., et al. (2001) · Science · doi:10.1126/science.1065810 · Cited by 2,138
The Tandem Affinity Purification (TAP) Method: A General Procedure of Protein Complex Purification
Puig, Ó., Caspary, F., Rigaut, G., Rutz, B., Bouveret, E., Bragado‐Nilsson, E., Wilm, M. S., & Séraphin, B. (2001) · Methods · doi:10.1006/meth.2001.1183 · Cited by 1,784
Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
Gottschling, D. E., Aparicio, O. M., Billington, B. L., & Zakian, V. A. (1990) · Cell · doi:10.1016/0092-8674(90)90141-z · Cited by 1,325
Histone H3.1 and H3.3 Complexes Mediate Nucleosome Assembly Pathways Dependent or Independent of DNA Synthesis
Tagami, H., Ray-Gallet, D., Almouzni, G., & Nakatani, Y. (2004) · Cell · doi:10.1016/s0092-8674(03)01064-x · Cited by 1,297
The Histone Variant H3.3 Marks Active Chromatin by Replication-Independent Nucleosome Assembly
Ahmad, K., & Henikoff, S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00542-7 · Cited by 1,154
FACT Facilitates Transcription-Dependent Nucleosome Alteration
Belotserkovskaya, R., Oh, S., Bondarenko, V. A., Orphanides, G., Studitsky, V. M., & Reinberg, D. (2003) · Science · doi:10.1126/science.1085703 · Cited by 869
Eukaryotic DNA mismatch repair
Kolodner, R. D., & Marsischky, G. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80013-6 · Cited by 861
The Establishment, Inheritance, and Function of Silenced Chromatin in Saccharomyces cerevisiae
Rusché, L. N., Kirchmaier, A. L., & Rine, J. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161547 · Cited by 726
Replication-Dependent Marking of DNA by PCNA Facilitates CAF-1-Coupled Inheritance of Chromatin
Shibahara, K., & Stillman, B. (1999) · Cell · doi:10.1016/s0092-8674(00)80661-3 · Cited by 703

Show all 64 references

Sorted by citations

PCNA, the Maestro of the Replication Fork
Moldovan, G.-L., Pfander, B., & Jentsch, S. (2007) · Cell · doi:10.1016/j.cell.2007.05.003 · Cited by 1,796
Histone core modifications regulating nucleosome structure and dynamics
Tessarz, P., & Kouzarides, T. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3890 · Cited by 1,018
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3Preprint
Drané, P., Ouararhni, K., Depaux, A., Shuaib, M., & Hamiche, A. (2010) · Genes & Development · doi:10.1101/gad.566910 · Cited by 709
Histone chaperone networks shaping chromatin function
Hammond, C. M., Strømme, C. B., Huang, H., Patel, D. J., & Groth, A. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.159 · Cited by 539
Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly
Li, Q., Zhou, H., Wurtele, H., Davies, B., Horazdovsky, B., Verreault, A., & Zhang, Z. (2008) · Cell · doi:10.1016/j.cell.2008.06.018 · Cited by 447
Self-citation
Histone chaperones: an escort network regulating histone traffic
de Koning, L., Corpet, A., Haber, J. E., & Almouzni, G. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1318 · Cited by 393
Chromosome Duplication in Saccharomyces cerevisiae
Bell, S. P., & Labib, K. P. M. (2016) · Genetics · doi:10.1534/genetics.115.186452 · Cited by 372
Chaperoning Histones during DNA Replication and Repair
Ransom, M., Dennehey, B. K., & Tyler, J. K. (2010) · Cell · doi:10.1016/j.cell.2010.01.004 · Cited by 345
Histone Chaperones: Assisting Histone Traffic and Nucleosome Dynamics
Gurard‐Levin, Z. A., Quivy, J., & Almouzni, G. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035536 · Cited by 333
Chromatin and Transcription in Yeast
Rando, O. J., & Winston, F. (2012) · Genetics · doi:10.1534/genetics.111.132266 · Cited by 269
Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis
Recht, J., Tsubota, T., Tanny, J. C., Diaz, R. L., Berger, J. M., Zhang, X., Garcia, B. A., Shabanowitz, J., Burlingame, A. L., Hunt, D. F., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601676103 · Cited by 252
Histone chaperones: 30 years from isolation to elucidation of the mechanisms of nucleosome assembly and disassembly
Eitoku, M., Sato, L., Senda, T., & Horikoshi, M. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7305-6 · Cited by 220
Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109
Fillingham, J., Recht, J., Silva, A. C., Suter, B., Emili, A., Štagljar, I., Krogan, N. J., Allis, C. D., Keogh, M., & Greenblatt, J. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00182-08 · Cited by 188
The histone shuffle: histone chaperones in an energetic dance
Das, C., Tyler, J. K., & Churchill, M. E. A. (2010) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2010.04.001 · Cited by 185
Acetylation of Lysine 56 of Histone H3 Catalyzed by RTT109 and Regulated by ASF1 Is Required for Replisome Integrity
Han, J., Zhou, H., Li, Z., Xu, R.-M., & Zhang, Z. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702496200 · Cited by 182
Self-citation
The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae
Gartenberg, M. R., & Smith, J. S. (2016) · Genetics · doi:10.1534/genetics.112.145243 · Cited by 148
Developmental roles of histone H3 variants and their chaperones
Filipescu, D., Szenker‐Ravi, E., & Almouzni, G. (2013) · Trends in Genetics · doi:10.1016/j.tig.2013.06.002 · Cited by 153
Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains
Schacherer, J., Ruderfer, D. M., Gresham, D., Dolinski, K. J., Botstein, D., & Kruglyak, L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000322 · Cited by 129
Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106
Su, D., Hu, Q., Li, Q., Thompson, J. R., Cui, G., Fazly, A., Davies, B. A., Botuyan, M. V., Zhang, Z., & Mer, G. (2012) · Nature · doi:10.1038/nature10861 · Cited by 128
Self-citation
The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathways
Mousson, F., Ochsenbein, F., & Mann, C. (2006) · Chromosoma · doi:10.1007/s00412-006-0087-z · Cited by 128
Histone H3 Variants and Their Chaperones During Development and Disease: Contributing to Epigenetic Control
Filipescu, D., Müller, S., & Almouzni, G. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013311 · Cited by 121
Regulation of Histone Gene Expression in Budding Yeast
Eriksson, P. R., Ganguli, D., Nagarajavel, V, & Clark, D. J. (2012) · Genetics · doi:10.1534/genetics.112.140145 · Cited by 114
The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly
Yang, J., Zhang, X., Feng, J., Leng, H., Li, S., Xiao, J., Liu, S., Xu, Z., Xu, J., Li, D., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2015.12.096 · Cited by 114
Two-Color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene Repression
Fillingham, J., Kainth, P., Lambert, J.-P., van Bakel, H., Tsui, K., Peña-Castillo, L., Nislow, C., Figeys, D., Hughes, T. R., Greenblatt, J., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.06.023 · Cited by 108
RPA binds histone H3-H4 and functions in DNA replication–coupled nucleosome assembly
Liu, S., Xu, Z., Leng, H., Zheng, P., Yang, J., Chen, K., Feng, J., & Li, Q. (2017) · Science · doi:10.1126/science.aah4712 · Cited by 108
The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents
Li, Q., Fazly, A., Zhou, H., Huang, S., Zhang, Z., & Stillman, B. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000684 · Cited by 108
Self-citation
Yeast Silent Mating Type Loci Form Heterochromatic Clusters through Silencer Protein-Dependent Long-Range Interactions
Miele, A., Bystricky, K., & Dekker, J. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000478 · Cited by 107
The Replication Fork: Understanding the Eukaryotic Replication Machinery and the Challenges to Genome Duplication
Leman, A. R., & Noguchi, E. (2013) · Genes · doi:10.3390/genes4010001 · Cited by 102
A Chromatin-Based Mechanism for Limiting Divergent Noncoding Transcription
Marquardt, S., Escalante-Chong, R., Pho, N. H., Wang, J., Churchman, L. S., Springer, M., & Buratowski, S. (2014) · Cell · doi:10.1016/j.cell.2014.04.036 · Cited by 103
Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1
Sauer, P. V., Gu, Y., Liu, W. H., Mattiroli, F., Panne, D., Luger, K., & Churchill, M. E. A. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky823 · Cited by 91
Histone H3K56 Acetylation, CAF1, and Rtt106 Coordinate Nucleosome Assembly and Stability of Advancing Replication Forks
Clemente‐Ruiz, M., González‐Prieto, R., & Prado, F. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002376 · Cited by 86
How is epigenetic information maintained through DNA replication?
Budhavarapu, V. N., Chavez-Tomar, M., & Tyler, J. K. (2013) · Epigenetics & Chromatin · doi:10.1186/1756-8935-6-32 · Cited by 77
A novel role for histone chaperones CAF‐1 and Rtt106p in heterochromatin silencing
Huang, S., Zhou, H., Tarara, J., & Zhang, Z. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601670 · Cited by 77
Self-citation
Regulation of histone gene transcription in yeast
Kurat, C. F., Recht, J., Radovani, E., Durbic, T., Andrews, B., & Fillingham, J. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1443-9 · Cited by 70
Defining the budding yeast chromatin‐associated interactome
Lambert, J., Fillingham, J., Siahbazi, M., Greenblatt, J., Baetz, K., & Figeys, D. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.104 · Cited by 73
Regulation of DNA replication-coupled histone gene expression
Mei, Q., Huang, J., Chen, W., Tang, J., Xu, C., Yu, Q., Cheng, Y., Ma, L., Yu, X., & Li, S. (2017) · Oncotarget · doi:10.18632/oncotarget.21887 · Cited by 69
Replication-Coupled Nucleosome Assembly and Positioning by ATP-Dependent Chromatin-Remodeling Enzymes
Yadav, T., & Whitehouse, I. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.059 · Cited by 62
The Replication-independent Histone H3-H4 Chaperones HIR, ASF1, and RTT106 Co-operate to Maintain Promoter Fidelity
Silva, A. C., Xu, X., Kim, H. S., Fillingham, J., Kislinger, T., Mennella, T. A., & Keogh, M. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.316489 · Cited by 60
The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways
Tscherner, M., Zwolanek, F., Jenull, S., Sedlazeck, F. J., Petryshyn, A., Frohner, I. E., Mavrianos, J., Chauhan, N., von Haeseler, A., & Kuchler, K. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1005218 · Cited by 57
Mechanisms of chromatin-based epigenetic inheritance
Du, W., Shi, G., Shan, C., Li, Z., Zhu, B., Jia, S., Li, Q., & Zhang, Z. (2022) · Science China Life Sciences · doi:10.1007/s11427-022-2120-1 · Cited by 53
Self-citation
Histone Chaperone Rtt106 Promotes Nucleosome Formation Using (H3-H4)2 Tetramers
Fazly, A., Li, Q., Hu, Q., Mer, G., Horazdovsky, B. F., & Zhang, Z. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.347450 · Cited by 56
Self-citation
A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Zhang, K., Gao, Y., Li, J., Burgess, R. J., Han, J., Liang, H., Zhang, Z., & Liu, Y. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw106 · Cited by 59
Self-citation
Diverse factors are involved in maintaining X chromosome inactivation
Chan, K. M., Zhang, H., Malureanu, L. A., van Deursen, J., & Zhang, Z. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107616108 · Cited by 53
Self-citation
A global requirement for the HIR complex in the assembly of chromatin
Amin, A. D., Vishnoi, N., & Prochasson, P. (2011) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2011.07.008 · Cited by 52
Fission yeast chromatin assembly factor 1 assists in the replication‐coupled maintenance of heterochromatin
Dohke, K., Miyazaki, S., Tanaka, K., Urano, T., Grewal, S. I. S., & Murakami, Y. (2008) · Genes to Cells · doi:10.1111/j.1365-2443.2008.01225.x · Cited by 50
The replisome guides nucleosome assembly during DNA replication
Zhang, W., Feng, J., & Li, Q. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00398-z · Cited by 50
Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing
Zunder, R. M., Antczak, A. J., Berger, J. M., & Rine, J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119095109 · Cited by 48
Exploring transcription regulation through cell-to-cell variability
Rinott, R., Jaimovich, A., & Friedman, N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1013148108 · Cited by 47
Histone chaperones in Arabidopsis and rice: genome-wide identification, phylogeny, architecture and transcriptional regulation
Tripathi, A. K., Singh, K., Pareek, A., & Singla-Pareek, S. L. (2015) · BMC Plant Biology · doi:10.1186/s12870-015-0414-8 · Cited by 47
Histones, histone chaperones and nucleosome assembly
Burgess, R. J., & Zhang, Z. (2010) · Protein & Cell · doi:10.1007/s13238-010-0086-y · Cited by 47
Self-citation
Clothing up DNA for all seasons: Histone chaperones and nucleosome assembly pathways
Rocha, W., & Verreault, A. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.006 · Cited by 49
All roads lead to chromatin: Multiple pathways for histone deposition
Li, Q., Burgess, R. J., & Zhang, Z. (2011) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2011.06.013 · Cited by 44
Self-citation
Restriction of histone gene transcription to S phase by phosphorylation of a chromatin boundary protein
Kurat, C. F., Lambert, J.-P., van Dyk, D., Tsui, K., van Bakel, H., Kaluarachchi, S., Friesen, H., Kainth, P., Nislow, C., Figeys, D., et al. (2011) · Genes & Development · doi:10.1101/gad.173427.111 · Cited by 41
Proliferating Cell Nuclear Antigen (PCNA) Is Required for Cell Cycle-regulated Silent Chromatin on Replicated and Nonreplicated Genes
Miller, A., Chen, J., Takasuka, T. E., Jacobi, J. L., Kaufman, P. D., Irudayaraj, J., & Kirchmaier, A. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.166918 · Cited by 41
Rtt105 functions as a chaperone for replication protein A to preserve genome stability
Li, S., Xu, Z., Xu, J., Zuo, L., Yu, C., Zheng, P., Gan, H., Wang, X., Li, L., Sharma, S., et al. (2018) · The EMBO Journal · doi:10.15252/embj.201899154 · Cited by 39
Structural Analysis of Rtt106p Reveals a DNA Binding Role Required for Heterochromatin Silencing
Liu, Y., Huang, H., Zhou, B. O., Wang, S., Hu, Y., Li, X., Liu, J., Zang, J., Niu, L., Wu, J., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.055996 · Cited by 39
The cell-cycle choreography of H3 variants shapes the genome
Delaney, K., Weiss, N., & Almouzni, G. (2023) · Molecular Cell · doi:10.1016/j.molcel.2023.08.030 · Cited by 39
Regulation of Replication Fork Advance and Stability by Nucleosome Assembly
Prado, F., & Maya‐Miles, D. (2017) · Genes · doi:10.3390/genes8020049 · Cited by 37
H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion
Rosón, J. N., Vitarelli, M. D. O., Costa-Silva, H. M., Pereira, K. S., Pires, D. D. S., Lopes, L. D. S., Cordeiro, B., Kraus, A. J., Cruz, K. N. T., Calderano, S. G., et al. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1009694 · Cited by 31
A Conserved Patch near the C Terminus of Histone H4 Is Required for Genome Stability in Budding Yeast
Yu, Y., Srinivasan, M., Nakanishi, S., Leatherwood, J., Shilatifard, A., & Sternglanz, R. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.01432-10 · Cited by 31
A Histone Code for Chromatin Assembly
Fillingham, J., & Greenblatt, J. (2008) · Cell · doi:10.1016/j.cell.2008.07.007 · Cited by 30
Chaperoning histones at the DNA repair dance
Chakraborty, U., Shen, Z.-J., & Tyler, J. K. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103240 · Cited by 31
Characterization of global gene expression during assurance of lifespan extension by caloric restriction in budding yeast
Choi, K.-M., Kwon, Y.-Y., & Lee, C. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.10.001 · Cited by 28
Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast
Hewawasam, G. S., Dhatchinamoorthy, K., Mattingly, M., Seidel, C. W., & Gerton, J. L. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky169 · Cited by 24
Mutations in the PCNA DNA Polymerase Clamp of Saccharomyces cerevisiae Reveal Complexities of the Cell Cycle and Ploidy on Heterochromatin Assembly
Brothers, M., & Rine, J. (2019) · Genetics · doi:10.1534/genetics.119.302452 · Cited by 24
The histone chaperone ASF1 is essential for sexual development in the filamentous fungus Sordaria macrospora
Gesing, S., Schindler, D., Fränzel, B., Wolters, D. A., & Nowrousian, M. (2012) · Molecular Microbiology · doi:10.1111/j.1365-2958.2012.08058.x · Cited by 24
CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor i with chromatin
Jeffery, D., Kakusho, N., You, Z., Gharib, M., Wyse, B. A., Drury, E., Weinreich, M., Thibault, P., Verreault, A., Masai, H., et al. (2015) · Cell Cycle · doi:10.4161/15384101.2014.973745 · Cited by 24
Global Replication-Independent Histone H4 Exchange in Budding Yeast
Linger, J. G., & Tyler, J. K. (2006) · Eukaryotic Cell · doi:10.1128/ec.00202-06 · Cited by 24
Direct Interplay among Histones, Histone Chaperones, and a Chromatin Boundary Protein in the Control of Histone Gene Expression
Zunder, R. M., & Rine, J. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00871-12 · Cited by 22
Linking DNA replication to heterochromatin silencing and epigenetic inheritance
Li, Q., & Zhang, Z. (2011) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmr107 · Cited by 22
Self-citation
The Saccharomyces cerevisiae Histone Chaperone Rtt106 Mediates the Cell Cycle Recruitment of SWI/SNF and RSC to the HIR-Dependent Histone Genes
Ferreira, M. E., Flaherty, K., & Prochasson, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021113 · Cited by 21
“Rtt106 can assemble nucleosomes in vitro and in vivo and functions in heterochromatin silencing [26,27], in replication-dependent nucleosome assembly [28], and has been linked to transcriptional elongation [27].”
Background
Forks on the Run: Can the Stalling of DNA Replication Promote Epigenetic Changes?
Rowlands, H. J., Dhavarasa, P., Cheng, A., & Yankulov, K. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00086 · Cited by 21
Identification of Elg1 interaction partners and effects on post-replication chromatin re-formation
Gali, V. K., Dickerson, D. R., Katou, Y., Fujiki, K., Shirahige, K., Owen‐Hughes, T., Kubota, T., & Donaldson, A. D. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007783 · Cited by 21
Histone Modifications During DNA Replication
Falbo, K. B., & Shen, X. (2009) · Molecules and Cells · doi:10.1007/s10059-009-0127-7 · Cited by 20
Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation
Jeffery, D., Wyse, B. A., Rehman, M. A., Brown, G. W., You, Z., Oshidari, R., Masai, H., & Yankulov, K. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt623 · Cited by 20
SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes
Nikolov, V. N., Malavia, D., & Kubota, T. (2022) · Nature Communications · doi:10.1038/s41467-022-29591-z · Cited by 16
AtMCM10 promotes DNA replication‐coupled nucleosome assembly in Arabidopsis
Zhao, X., Wang, J., Jin, D., Cheng, J., Chen, H., Li, Z., Wang, Y., Lou, H., Zhu, J., Du, X., et al. (2022) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13438 · Cited by 17
Cell cycle regulation of silent chromatin formation
Young, T. J., & Kirchmaier, A. L. (2011) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2011.10.006 · Cited by 16
PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions
Wilson, R. H. C., Biasutto, A., Wang, L., Fischer, R., Baple, E. L., Crosby, A. H., Mancini, E. J., & Green, C. (2017) · DNA repair · doi:10.1016/j.dnarep.2016.12.003 · Cited by 15
A novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function
Rosas, R., Aguilar, R. R., Arslanovic, N., Seck, A., Smith, D. J., Tyler, J. K., & Churchill, M. E. A. (2023) · eLife · doi:10.7554/elife.83538 · Cited by 13
The SCFDia2 Ubiquitin E3 Ligase Ubiquitylates Sir4 and Functions in Transcriptional Silencing
Burgess, R. J., Zhou, H., Han, J., Li, Q., & Zhang, Z. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002846 · Cited by 13
Self-citation
Histone Chaperones in Chromatin Dynamics
Shandilya, J., Gadad, S. S., Swaminathan, V., & Kundu, T. K. (2007) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/1-4020-5466-1_6 · Cited by 11
A link between Sas2-mediated H4 K16 acetylation, chromatin assembly in S-phase by CAF-I and Asf1, and nucleosome assembly by Spt6 during transcription
Reiter, C. G., Heise, F., Chung, H., & Ehrenhofer‐Murray, A. E. (2015) · FEMS Yeast Research · doi:10.1093/femsyr/fov073 · Cited by 11
Cell-Cycle–Dependent Chromatin Dynamics at Replication Origins
Li, Y., Hartemink, A. J., & MacAlpine, D. M. (2021) · Genes · doi:10.3390/genes12121998 · Cited by 10
Dare to challenge the silence? Telomeric gene silencing revisited
Yankulov, K. (2011) · Nucleus · doi:10.4161/nucl.2.6.17710 · Cited by 11
Mutual Interdependence of MSI1 (CAC3) and YAK1 in Saccharomyces cerevisiae
Pratt, Z. L., Drehman, B. J., Miller, M. E., & Johnston, S. D. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2007.01.046 · Cited by 10
Chromatin Modifiers Alter Recombination Between Divergent DNA Sequences
Chakraborty, U., Mackenroth, B., Shalloway, D. I., & Alani, E. (2019) · Genetics · doi:10.1534/genetics.119.302395 · Cited by 7
Yeast mismatch repair components are required for stable inheritance of gene silencing
Liu, Q., Zhu, X., Lindström, M., Shi, Y., Zheng, J., Hao, X., Gustafsson, C. M., & Liu, B. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008798 · Cited by 8
Cac1 WHD and PIP domains have distinct roles in replisome progression and genomic stability
Tsirkas, I., Dovrat, D., Yang, L., Kalyva, A., Lotysh, D., Li, Q., & Aharoni, A. (2020) · Current Genetics · doi:10.1007/s00294-020-01113-8 · Cited by 9
Chromatin dynamics and DNA replication roadblocks
Hammond-Martel, I., Verreault, A., & Würtele, H. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103140 · Cited by 9
Histone chaperones: Variety and functions
Valieva, M. E., Feofanov, A. V., & Studitsky, V. M. (2016) · Moscow University Biological Sciences Bulletin · doi:10.3103/s0096392516030123 · Cited by 6
Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Phosphorylation of Chromatin Assembly Factor CAF-1 in Saccharomyces cerevisiae
Young, T. J., Cui, Y., Irudayaraj, J., & Kirchmaier, A. L. (2019) · Genetics · doi:10.1534/genetics.118.301858 · Cited by 8
CAF-1 and Rtt101p function within the replication-coupled chromatin assembly network to promote H4 K16ac, preventing ectopic silencing
Young, T. J., Cui, Y., Pfeffer, C. M., Hobbs, E., Liu, W., Irudayaraj, J., & Kirchmaier, A. L. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1009226 · Cited by 5
Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing
Rowlands, H. J., Shaban, K., Cheng, A., Foster, B., & Yankulov, K. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1673100 · Cited by 5
The Ddc1-Mec3-Rad17 Sliding Clamp Regulates Histone-Histone Chaperone Interactions and DNA Replication-coupled Nucleosome Assembly in Budding Yeast
Burgess, R. J., Han, J., & Zhang, Z. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.552463 · Cited by 6
Self-citation
Histone chaperone Spt16p is required for heterochromatin mediated silencing in budding yeast
Yan, X., Yang, J., Xu, J., Feng, J., & Li, Q. (2017) · Protein & Cell · doi:10.1007/s13238-017-0485-4 · Cited by 5
Histone H2B.V demarcates strategic regions in the Trypanosoma cruzi genome, associates with a bromodomain factor and affects parasite differentiation and host cell invasionPreprint
Rosón, J. N., Vitarelli, M. D. O., Costa-Silva, H. M., Pereira, K. S., Pires, D. D. S., Lopes, L. D. S., Cordeiro, B., Kraus, A. J., Cruz, K. N. T., Calderano, S. G., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.08.447515 · Cited by 5
The Role of the MCM2-7 Helicase Subunit MCM2 in Epigenetic Inheritance
Jia, J., & Yu, C. (2024) · Biology · doi:10.3390/biology13080572 · Cited by 5
The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity
Bragantini, B., Charron, C., Bourguet, M., Paul, A., Tiotiu, D., Rothé, B., Marty, H., Terral, G., Hessmann, S., Decourty, L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22077-4 · Cited by 6
Recent Perspectives on the Roles of Histone Chaperones in Transcription Regulation
Reddy, B. A., Jerónimo, C., & Robert, F. (2017) · Current Molecular Biology Reports · doi:10.1007/s40610-017-0049-7 · Cited by 4

Authors: Huang, S., Zhou, H., Katzmann, D., Hochstrasser, M., Atanasova, E., & Zhang, Z.
Affiliations: Mayo Clinic (US)
ORCID: Zhou, Hui
Katzmann, David
Hochstrasser, Mark
Zhang, Zhiguo
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 2005-09-12
Volume: 102
Issue: 38
Pages: 13410-13415
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.0506176102
PMC: PMC1224646
OpenAlex: W2031481332
Cited by: 130
References: 64
Citations by year: 2026: 3 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 5 · 2021: 9 · 2020: 4 · 2019: 5 · 2018: 6 · 2017: 8 · 2016: 8 · 2015: 5 · 2014: 6 · 2013: 7 · 2012: 7
FWCI: 2.13
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Cancer Research UK
University of Toronto
National Institutes of Health
National Institute of General Medical Sciences (R01GM046904, R37GM046904, GM-46904)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Structure and Function
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
Keywords: histone chaperone, heterochromatin silencing, epigenetic inheritance, CAF-1, nucleosome assembly, histone H3, histone H4, S phase, Saccharomyces cerevisiae, Sir proteins
MeSH terms: Histones, Ribonucleases, Saccharomyces cerevisiae, Gene Expression Regulation, Fungal, S Phase, Gene Deletion, Proliferating Cell Nuclear Antigen, Molecular Chaperones, Gene Silencing, Saccharomyces cerevisiae Proteins, Chromatin Assembly and Disassembly, Epigenesis, Genetic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks