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Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men
Open accessAbstract
A whole-genome admixture scan in 1,597 African Americans identified a 3.8 Mb interval on chromosome 8q24 as significantly associated with susceptibility to prostate cancer [logarithm of odds (LOD) = 7.1]. The increased risk because of inheriting African ancestry is greater in men diagnosed before 72 years of age ( P < 0.00032) and may contribute to the epidemiological observation that the higher risk for prostate cancer in African Americans is greatest in younger men (and attenuates with older age). The same region was recently identified through linkage analysis of prostate cancer, followed by fine-mapping. We strongly replicated this association ( P < 4.2 × 10 −9 ) but find that the previously described alleles do not explain more than a fraction of the admixture signal. Thus, admixture mapping indicates a major, still-unidentified risk gene for prostate cancer at 8q24, motivating intense work to find it.
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Citations
Cites
A haplotype map of the human genome
The International HapMap Consortium (2005) · Nature · doi:10.1038/nature04226 · Cited by 5,858
Jemal, A., Siegel, R. L., Ward, E. M., Murray, T., Xu, J., Smigal, C., & Thun, M. J. (2006) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.2.106 · Cited by 5,309
A Multiethnic Cohort in Hawaii and Los Angeles: Baseline Characteristics
Kolonel, L. N., Henderson, B. E., Hankin, J. H., Nomura, A. M. Y., Wilkens, L. R., Pike, M. C., Stram, D. O., Monroe, K. R., Earle, M. E., & Nagamine, F. S. (2000) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a010213 · Cited by 1,017
Self-citationMyc-driven murine prostate cancer shares molecular features with human prostate tumors
Ellwood‐Yen, K., Graeber, T. G., Wongvipat, J., Iruela‐Arispe, M. L., Zhang, J., Matusik, R. J., THOMAS, G. V., & Sawyers, C. L. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00197-1 · Cited by 816
A common variant associated with prostate cancer in European and African populations
Amundadottir, L. T., Sulem, P., Gudmundsson, J., Helgason, A., Baker, A., Agnarsson, B. A., Sigurdsson, A., Benediktsdottir, K. R., Cazier, J.-B., Sainz, J., et al. (2006) · Nature Genetics · doi:10.1038/ng1808 · Cited by 787
Self-citationHighly Parallel SNP GenotypingPreprint
Fan, J., Oliphant, A., Shen, R., Kermani, B. G., GARCIA, F., Gunderson, K. L., Hansen, T. F., Steemers, F. J., BUTLER, S. L., Deloukas, P., et al. (2003) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2003.68.69 · Cited by 641
Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization.
Visakorpi, T., Kallioniemi, A. H., Syvänen, A. C., HYYTINEN, E.-R., Karhu, R., Tammela, T. L. J., Isola, J. J., & Kallioniemi, O. (1995) · PubMed · Cited by 480
Methods for High-Density Admixture Mapping of Disease Genes
Patterson, N. J., Hattangadi, N., Lane, B., Lohmueller, K. E., Hafler, D. A., Oksenberg, J. R., Hauser, S. L., Smith, M. W., O’Brien, S. J., Altshuler, D., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/420871 · Cited by 475
Self-citationA High-Density Admixture Map for Disease Gene Discovery in African Americans
Smith, M. W., Patterson, N., Lautenberger, J. A., Truelove, A. L., McDonald, G. J., Waliszewska, A., Kessing, B. D., Malasky, M. J., Scafe, C., Le, E., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/420856 · Cited by 459
Self-citationDesign and Analysis of Admixture Mapping Studies
Hoggart, C. J., Shriver, M. D., Kittles, R. A., Clayton, D. G., & McKeigue, P. (2004) · The American Journal of Human Genetics · doi:10.1086/420855 · Cited by 304
Research works printed but not linked: 4
- CH Bunker, AL Patrick, BR Konety, R Dhir, AM Brufsky, CA Vivas, MJ Becich, DL Trump, LH Kuller Cancer Epidemiol Biomarkers Prev 11, 726–729 (2002).
- PM McKeigue Am J Hum Genet 60, 188–196 (1997).
- DC Rife Am J Hum Genet 6, 26–33 (1954).
- T Visakorpi, AH Kallioniemi, AC Syvanen, ER Hyytinen, R Karhu, T Tammela, JJ Isola, OP Kallioniemi Cancer Res 55, 342–347 (1995).
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Hamano, T., Matsui, H., Sekine, Y., Ohtake, N., Nakata, S., & Suzuki, K. (2010) · The Journal of Urology · doi:10.1016/j.juro.2010.03.102 · Cited by 13
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Helfand, B. T., Loeb, S., Meeks, J. J., Fought, A. J., Kan, D., & Catàlona, W. J. (2009) · The Journal of Urology · doi:10.1016/j.juro.2009.01.109 · Cited by 13
Zhang, W., & Zhang, K. (2023) · Cancer Informatics · doi:10.1177/11769351231168006 · Cited by 12
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Helfand, B. T., Loeb, S., Kan, D., & Catàlona, W. J. (2010) · British Journal of Urology · doi:10.1111/j.1464-410x.2010.09440.x · Cited by 12
Burastero, S. E., Masciulli, A., & Villa, A. M. (2010) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2010.07.004 · Cited by 12
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Tandon, A., Chen, C., Penman, A., Hancock, H., James, M., Husain, D., Andreoli, C., Li, X.-H., Kuo, J., Idowu, O., et al. (2015) · Investigative Ophthalmology and Visual Science · doi:10.1167/iovs.15-16674 · Cited by 12
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Pichardo, M. S., Smith, C. J., Dorsey, T. H., Loffredo, C. A., & Ambs, S. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-18-0242 · Cited by 11
Ziyatdinov, A., Parker, M. M., Vaysse, A., Beaty, T. H., Kraft, P. L., Cho, M. H., & Aschard, H. (2019) · European Journal of Human Genetics · doi:10.1038/s41431-019-0545-8 · Cited by 12
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Gompert, Z. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151047 · Cited by 11
Bertoméu-Sánchez, S., & Serebrisky, T. (2018) · Springer eBooks · doi:10.1007/978-3-319-98515-2_8 · Cited by 12
Ferrari, M. G., Ganaie, A. A., Shabenah, A., Mansini, A. P., Wang, L., Murugan, P. J., Davicioni, E., Wang, J., Deng, Y., Hoeppner, L. H., et al. (2020) · The Prostate · doi:10.1002/pros.24018 · Cited by 11
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Parida, L., Utro, F., Yörükoğlu, D., Carrieri, A. P., Kuhn, D. N., & Basu, S. (2015) · Lecture notes in computer science · doi:10.1007/978-3-319-16706-0_27 · Cited by 11
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Ateeq, B., Bhatia, V., & Goel, S. (2016) · Trends in cancer · doi:10.1016/j.trecan.2016.01.005 · Cited by 11
Camp, N. J., Farnham, J. M., Allen‐Brady, K., & Cannon‐Albright, L. (2007) · The Prostate · doi:10.1002/pros.20631 · Cited by 11
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Kaushal, J., Raut, P., Muniyan, S., Siddiqui, J. A., Alsafwani, Z. W., Seshacharyulu, P., Nair, S. S., Tewari, A. K., & Batra, S. K. (2024) · Cancer and Metastasis Reviews · doi:10.1007/s10555-024-10193-8 · Cited by 10
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Batai, K., & Kittles, R. A. (2013) · Race and Social Problems · doi:10.1007/s12552-013-9094-x · Cited by 10
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Cook, M. B., Graubard, B. I., Quraishi, S. M., Yeager, M., Chanock, S. J., Crenshaw, A., Erickson, R. L., Rubertone, M. V., Thomas, G. D., & McGlynn, K. A. (2008) · Human Genetics · doi:10.1007/s00439-008-0491-y · Cited by 10
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Dewal, N., Hu, Y., Freedman, M. L., LaFramboise, T., & Pe’er, I. (2011) · Genome Research · doi:10.1101/gr.122564.111 · Cited by 10
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Jack, J., Havener, T. M., McLeod, H. L., Motsinger‐Reif, A. A., & Foster, M. C. (2015) · Pharmacogenomics · doi:10.2217/pgs.15.85 · Cited by 10
Bree, K. K., Hensley, P. J., & Pettaway, C. A. (2021) · Urology · doi:10.1016/j.urology.2021.08.017 · Cited by 8
Hardiman, G., Savage, S. J., Hazard, E. S., da Silveira, W. A., Morgan, R. A., Harris, A., Jefferson, M. S., Wilson, R. C., Caulder, S., Ambrose, L., et al. (2021) · Cancers · doi:10.3390/cancers13205143 · Cited by 9
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Divers, J., Moossavi, S., Langefeld, C. D., & Freedman, B. I. (2008) · PubMed · Cited by 9
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Branković, A., Brajušković, G. N., Mircetic, J., Dobrijević, Z., Kalaba, P., Vukotić, V. D., Tomović, S. M., Cerović, S. J., Radojicic, Z. A., Pavicevic, D. S., et al. (2013) · Pathology & Oncology Research · doi:10.1007/s12253-013-9617-1 · Cited by 9
Donin, N. M., Loeb, S., Cooper, P. R., Roehl, K. A., Baumann, N. A., Catàlona, W. J., & Helfand, B. T. (2014) · British Journal of Urology · doi:10.1111/bju.12647 · Cited by 8
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Netto, G. J. (2015) · Surgical pathology clinics · doi:10.1016/j.path.2015.08.003 · Cited by 8
Chan, T. F., Rui, X., Conti, D. V., Fornage, M., Graff, M., Haessler, J., Haiman, C., Highland, H. M., Jung, S. Y., Kenny, E. E., et al. (2023) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2023.09.012 · Cited by 10
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Baron, B. (2012) · InTech eBooks · doi:10.5772/2152 · Cited by 7
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Price, D. K., & Hsing, A. W. (2010) · Springer eBooks · doi:10.1007/978-1-60327-829-4_4 · Cited by 7
Gu, J. H., Chery, L. J., Nogueras‐González, G. M., Huff, C. D., Strom, S. S., Jones, J. A., Griffith, D. P., Canfield, S. E., Wang, X., Huang, X., et al. (2024) · The Prostate · doi:10.1002/pros.24686 · Cited by 6
Nelson, W. G., Antonarakis, E. S., Carter, H. B., Marzo, A. M. D., & DeWeese, T. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-47674-4.00081-5 · Cited by 6
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Offit, K., Thom, P., & Bernstein, D. B. (2008) · Elsevier eBooks · doi:10.1016/b978-0-443-06694-8.50015-4 · Cited by 7
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Clarke, G. M., & Whittemore, A. S. (2007) · Genetic Epidemiology · doi:10.1002/gepi.20239 · Cited by 6
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Non, A. L., Gravlee, C. C., & Mulligan, C. J. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2009.12.014 · Cited by 6
Chai, Z., Yan, S., Li, H., Dong, X., Li, S., Fan, Y., Dong, Z., He, Z., Zhou, J., Lei, P., et al. (2025) · BMC Public Health · doi:10.1186/s12889-025-25694-6 · Cited by 5
Lisi, A., & Campbell, M. C. (2024) · Bioinformatics · doi:10.1093/bioinformatics/btae616 · Cited by 5
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Lange, E. M., Ribado, J. V., Zuhlke, K. A., Johnson, A., Keele, G. R., Li, J., Wang, Y., Duan, Q., Li, G., Gao, Z., et al. (2015) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-0995 · Cited by 5
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Wang, X., Xiao, R., Zhu, X., & Li, M. (2016) · Human Heredity · doi:10.1159/000446956 · Cited by 5
Mandal, D. M., Sartor, O. A., Halton, S., Mercante, D., Wilson, J., & Rayford, W. (2008) · Prostate Cancer and Prostatic Diseases · doi:10.1038/pcan.2008.5 · Cited by 5
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Schrader, K. A., Sharaf, R., Alanee, S. R., & Offit, K. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-2865-7.00012-6 · Cited by 5
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Kiemeney, L. A. L. M. (2007) · European Urology · doi:10.1016/j.eururo.2007.06.013 · Cited by 5
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Wu, X., & Gu, J. H. (2008) · CRC Press eBooks · doi:10.3109/9781420052923-10 · Cited by 5
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Oskina, N. A., Boyarskikh, U. A., Lazarev, A. F., Петрова, В. Д., Иванович, Г. Д., Тоначева, О. Г., Израйлевна, Л. Г., & Филипенко, М. Л. (2012) · Molecular Biology · doi:10.1134/s0026893312020124 · Cited by 4
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Rinckleb, A. E., Surowy, H., Luedeke, M., Varga, D., Schrader, M. G., Hoegel, J. J., Vogel, W., & Maier, C. (2012) · DNA repair · doi:10.1016/j.dnarep.2012.05.003 · Cited by 4
Edwards, A. O., Lee, S. J., Fridley, B. L., & Tosakulwong, N. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002510 · Cited by 5
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Karimi, F., Amiri-Moghaddam, S. M., Bagheri, Z., Bahrami, A. R., Goshayeshi, L., Allahyari, A., Mirsadraee, M., Fanipakdel, A., Bari, A., Torghabeh, A. E., et al. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06249-5 · Cited by 3
Booth, T. J. (2020) · Archaeological Dialogues · doi:10.1017/s1380203820000033 · Cited by 3
Platz, E. A. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0737 · Cited by 3
O’Malley, P. (2017) · Molecular pathology library · doi:10.1007/978-3-319-64096-9_2 · Cited by 3
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Eeles, R. A., Kote‐Jarai, Z., Guy, M., & Easton, D. F. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0449-2_8 · Cited by 3
The Application of the HapMap to Diabetic Nephropathy and Other Causes of Chronic Renal Failure
Iyengar, S. K., & Adler, S. G. (2007) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2007.01.003 · Cited by 3
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Criswell, L. A., & Seldin, M. F. (2008) · Arthritis & Rheumatism · doi:10.1002/art.23192 · Cited by 3
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Cheng, C.-Y., Reich, D., Haiman, C. A., Tandon, A., Patterson, N., Elizabeth, S., Akylbekova, E. L., Brancati, F. L., Coresh, J., Boerwinkle, E., et al. (2012) · PLoS ONE · doi:10.1371/annotation/52e53d8e-a4bd-4419-951a-75ddcbaf6c5d · Cited by 2
Self-citationOld vs. new local ancestry inference in HCHS/SOL: a comparative study
Chen, X., Wang, H., Broce, I., Dale, A. M., Yu, B., Zhou, L. Y., Li, X., Argos, M., Daviglus, M. L., Cai, J., et al. (2025) · Human Molecular Genetics · doi:10.1093/hmg/ddaf093 · Cited by 2
Insights into inherited genetic variations and genetic ancestry of patients with high-risk melanoma
Tarhini, A. A., Khaksar, M. A., Chen, Z., Lee, S. J., Hodi, F. S., Li, T., Monteiro, A. N., STREICHER, H. Z., Sondak, V. K., Wang, X., et al. (2026) · Melanoma Research · doi:10.1097/cmr.0000000000001087 · Cited by 2
Association between genetic variations at 8q24 and prostate cancer risk in Mexican Men
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Admixture Aberration Analysis: Application to Mapping in Admixed Population Using Pooled DNA
Bercovici, S., & Geiger, D. (2011) · Journal of Computational Biology · doi:10.1089/cmb.2010.0250 · Cited by 2
Discovery and Characterization of Cancer Genetic Susceptibility Alleles
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Metadata
- Authors
- Freedman, M. L., Haiman, C. A., Patterson, N., McDonald, G. J., Tandon, A., Waliszewska, A., Penney, K., Steen, R. G., Ardlie, K., John, E. M., Oakley-Girvan, I., Whittemore, A. S., Cooney, K. A., Ingles, S. A., Altshuler, D., Henderson, B. E., & Reich, D.
- Affiliations
- Broad Institute (US)
- University of Southern California (US)
- Harvard University (US)
- Cancer Prevention Institute of California (US)
- Stanford Medicine (US)
- University of Michigan (US)
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2006-09-19
- Volume
- 103
- Issue
- 38
- Pages
- 14068-14073
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC1599913
- OpenAlex
- W1995404520
- Cited by
- 612
- References
- 26
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 14 · 2023: 18 · 2022: 15 · 2021: 20 · 2020: 33 · 2019: 13 · 2018: 17 · 2017: 25 · 2016: 21 · 2015: 22 · 2014: 27 · 2013: 29 · 2012: 37
- FWCI
- 36.26
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- University Libraries (University of Maryland) (submittedVersion)
- Digital Repository at the University of Maryland (University of Maryland College Park)
- Funders
- U.S. Department of Defense (CA63464)
- University of Southern California (CA63464)
- Rockefeller Brothers Fund
- University of Michigan
- Broad Institute
- National Institutes of Health (CA63464, CA69568, CA79596)
- University of Michigan Comprehensive Cancer Center
- National Human Genome Research Institute (K01HG002758, HG02758)
- National Cancer Institute (CA 69568, CA63464, U01CA063464, CA79596, CA67044, R01CA067044, R01CA079596, R01CA063464, P50CA069568, U01CA067044)
- National Center for Research Resources
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Prostate Cancer Treatment and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Keywords
- prostate cancer, 8q24, African American men, admixture mapping, genetic susceptibility, African ancestry, age at diagnosis
- MeSH terms
- Aged, Alleles, Black or African American, Chromosome Mapping, Chromosomes, Human, Pair 8, Genetic Markers, Genotype, Humans, Male, Middle Aged, Neoplasm Staging, Phenotype, Prostatic Neoplasms, Risk Factors, Genetic Predisposition to Disease
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