The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors
Open accessAbstract
Novel nanomaterials for bioassay applications represent a rapidly progressing field of nanotechnology and nanobiotechnology. Here, we present an exploration of single-walled carbon nanotubes as a platform for investigating surface–protein and protein–protein binding and developing highly specific electronic biomolecule detectors. Nonspecific binding on nanotubes, a phenomenon found with a wide range of proteins, is overcome by immobilization of polyethylene oxide chains. A general approach is then advanced to enable the selective recognition and binding of target proteins by conjugation of their specific receptors to polyethylene oxide-functionalized nanotubes. This scheme, combined with the sensitivity of nanotube electronic devices, enables highly specific electronic sensors for detecting clinically important biomolecules such as antibodies associated with human autoimmune diseases.
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Cites
Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization
Chen, R. J., Zhang, Y., Wang, D., & Dai, H. (2001) · Journal of the American Chemical Society · doi:10.1021/ja010172b · Cited by 2,534
A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
Ostuni, E., Chapman, R. G., Holmlin, R. E., Takayama, S., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010384m · Cited by 1,799
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Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
Hammock, M. L., Chortos, A., Tee, B. C. ‐., Tok, J. B. ‐., & Bao, Z. (2013) · Advanced Materials · doi:10.1002/adma.201302240 · Cited by 2,396
Electrical detection of single viruses
Patolsky, F., Zheng, G., Hayden, O., Lakadamyali, M., Zhuang, X., & Lieber, C. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406159101 · Cited by 1,258
Systems Biology and New Technologies Enable Predictive and Preventative Medicine
Hood, L., Heath, J. R., Phelps, M. E., & Lin, B. (2004) · Science · doi:10.1126/science.1104635 · Cited by 1,108
Metadata
- Authors
- Chen, R. J., Bangsaruntip, S., Drouvalakis, K. A., Wong Shi Kam, N., Shim, M., Li, Y., Kim, W., Utz, P. J., & Dai, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-04-15
- Volume
- 100
- Issue
- 9
- Pages
- 4984-4989
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2164370375
- Cited by
- 1,442
- References
- 2
- FWCI
- 77.10
- Type
- journal article
- Language
- en
- Open access
- green
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- Chen, R. J., Bangsaruntip, S., Drouvalakis, K. A., Wong Shi Kam, N., Shim, M., Li, Y., Kim, W., Utz, P. J., & Dai, H. (2003). Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0837064100
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