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The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors

Open access
Chen, Robert J., Bangsaruntip, Sarunya, Drouvalakis, Katerina A., Wong Shi Kam, Nadine, Shim, Moonsub, Li, Yiming, Kim, Woong, Utz, Paul J., Dai, Hongjie·2003·Proceedings of the National Academy of Sciences

Abstract

Novel nanomaterials for bioassay applications represent a rapidly progressing field of nanotechnology and nanobiotechnology. Here, we present an exploration of single-walled carbon nanotubes as a platform for investigating surface–protein and protein–protein binding and developing highly specific electronic biomolecule detectors. Nonspecific binding on nanotubes, a phenomenon found with a wide range of proteins, is overcome by immobilization of polyethylene oxide chains. A general approach is then advanced to enable the selective recognition and binding of target proteins by conjugation of their specific receptors to polyethylene oxide-functionalized nanotubes. This scheme, combined with the sensitivity of nanotube electronic devices, enables highly specific electronic sensors for detecting clinically important biomolecules such as antibodies associated with human autoimmune diseases.

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Metadata

Authors
Chen, R. J., Bangsaruntip, S., Drouvalakis, K. A., Wong Shi Kam, N., Shim, M., Li, Y., Kim, W., Utz, P. J., & Dai, H.
Venue
Proceedings of the National Academy of Sciences
Published
2003-04-15
Volume
100
Issue
9
Pages
4984-4989
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2164370375
Cited by
1,442
References
2
FWCI
77.10
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. https://app.cochat.ai/papers/10.1073/pnas.0837064100
The paper
Chen, R. J., Bangsaruntip, S., Drouvalakis, K. A., Wong Shi Kam, N., Shim, M., Li, Y., Kim, W., Utz, P. J., & Dai, H. (2003). Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0837064100

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