The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Complex regulation of the TIR1/AFB family of auxin receptors
Open accessAbstract
Auxin regulates most aspects of plant growth and development. The hormone is perceived by the TIR1/AFB family of F-box proteins acting in concert with the Aux/IAA transcriptional repressors. Arabidopsis plants that lack members of the TIR1/AFB family are auxin resistant and display a variety of growth defects. However, little is known about the functional differences between individual members of the family. Phylogenetic studies reveal that the TIR1/AFB proteins are conserved across land plant lineages and fall into four clades. Three of these subgroups emerged before separation of angiosperms and gymnosperms whereas the last emerged before the monocot-eudicot split. This evolutionary history suggests that the members of each clade have distinct functions. To explore this possibility in Arabidopsis , we have analyzed a range of mutant genotypes, generated promoter swap transgenic lines, and performed in vitro binding assays between individual TIR1/AFB and Aux/IAA proteins. Our results indicate that the TIR1/AFB proteins have distinct biochemical activities and that TIR1 and AFB2 are the dominant auxin receptors in the seedling root. Further, we demonstrate that TIR1 , AFB2 , and AFB3 , but not AFB1 exhibit significant posttranscriptional regulation. The microRNA miR393 is expressed in a pattern complementary to that of the auxin receptors and appears to regulate TIR1 / AFB expression. However our data suggest that this regulation is complex. Our results suggest that differences between members of the auxin receptor family may contribute to the complexity of auxin response.
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Cites
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Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana
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Auxin: Regulation, Action, and Interaction
WOODWARD, A. W. (2005) · Annals of Botany · doi:10.1093/aob/mci083 · Cited by 2,340
The F-box protein TIR1 is an auxin receptor
Dharmasiri, N., Dharmasiri, S., & Estelle, M. (2005) · Nature · doi:10.1038/nature03543 · Cited by 2,083
Self-citationA Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling
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Self-citationThe Arabidopsis F-box protein TIR1 is an auxin receptor
Kepinski, S., & Leyser, O. (2005) · Nature · doi:10.1038/nature03542 · Cited by 1,714
Mechanism of auxin perception by the TIR1 ubiquitin ligase
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Self-citationHighly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis
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Cited by
A novel sensor to map auxin response and distribution at high spatio-temporal resolution
Brunoud, G., Wells, D. M., Oliva, M., Larrieu, A., Mirabet, V., Burrow, A. H., Beeckman, T., Kepinski, S., Traas, J., Bennett, M. J., et al. (2012) · Nature · doi:10.1038/nature10791 · Cited by 741
Self-citationThe auxin signalling network translates dynamic input into robust patterning at the shoot apex
Vernoux, T., Brunoud, G., Farcot, E., Morin, V., Van den Daele, H., Legrand, J., Oliva, M., Das, P., Larrieu, A., Wells, D., et al. (2011) · Molecular Systems Biology · doi:10.1038/msb.2011.39 · Cited by 576
Self-citationYesbolatova, A., Saito, Y., Kitamoto, N., Makino-Itou, H., Ajima, R., Nakano, R., Nakaoka, H., Fukui, K., Gamo, K., Tominari, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19532-z · Cited by 533
SCFTIR1/AFB-Based Auxin Perception: Mechanism and Role in Plant Growth and Development
Salehin, M., Bagchi, R., & Estelle, M. (2015) · The Plant Cell · doi:10.1105/tpc.114.133744 · Cited by 462
Self-citationda Costa, C. T., de Almeida, M. R., Ruedell, C. M., Schwambach, J., Maraschin, F. S., & Fett-Neto, A. G. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00133 · Cited by 417
Metadata
- Authors
- Parry, G., Calderon-Villalobos, L. I., Prigge, M., Peret, B., Dharmasiri, S., Itoh, H., Lechner, E., Gray, W. M., Bennett, M., & Estelle, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2009-12-29
- Volume
- 106
- Issue
- 52
- Pages
- 22540-22545
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2031530658
- Cited by
- 481
- References
- 29
- FWCI
- 25.69
- Type
- journal article
- Language
- en
- Open access
- green
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