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Audiovestibular findings in patients with Vogt-Koyanagi-Harada disease

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IL-10/HMOX1 Signaling Modulates Cochlear Inflammation via Negative Regulation of MCP-1/CCL2 Expression in Cochlear Fibrocytes

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CNS Resident Innate Immune Cells: Guardians of CNS Homeostasis

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TNFSF15 inhibits VEGF‐stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation

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Suppression of Connexin 43 Leads to Strial Vascular Hyper-Permeability, Decrease in Endocochlear Potential, and Mild Hearing Loss

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Cochlear Inflammaging in Relation to Ion Channels and Mitochondrial Functions

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MITF variants cause nonsyndromic sensorineural hearing loss with autosomal recessive inheritance

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Spatial architecture of the cochlear immune microenvironment in noise-induced and age-related sensorineural hearing loss

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Pituitary adenylate cyclase–activating polypeptide (PACAP-38) plays an inhibitory role against inflammation induced by chemical damage to zebrafish hair cells

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Sex Differences in Otolaryngology: Focus on the Emerging Role of Estrogens in Inflammatory and Pro-Resolving Responses

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Sudden sensorineural hearing loss: Is there a connection with inner ear electrolytic disorders? A literature review

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Platelet-Derived Growth Factor Subunit B Signaling Promotes Pericyte Migration in Response to Loud Sound in the Cochlear Stria Vascularis

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The Blood-Labyrinth Barrier: Non-Invasive Delivery Strategies for Inner Ear Drug Delivery

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Tumor necrosis factor-α mediated inflammation versus apoptosis in age-related hearing loss

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ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity

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Acoustic Trauma Causes Cochlear Pericyte-to-Myofibroblast–Like Cell Transformation and Vascular Degeneration, and Transplantation of New Pericytes Prevents Vascular Atrophy

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Associations between Age-Related Hearing Loss and DietaryAssessment Using Data from Korean National Health andNutrition Examination Survey

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Immunohistochemical localization of OCT2 in the cochlea of various species

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Wide coverage of the body surface by melanocyte-mediated skin pigmentation

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Purinergic Signaling and Cochlear Injury-Targeting the Immune System?

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Reactive Oxygen Species–Related Disruptions to Cochlear Hair Cell and Stria Vascularis Consequently Leading to Radiation-Induced Sensorineural Hearing Loss

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Role of Free Radical Formation in Murine Cytomegalovirus–Induced Hearing Loss

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Partial corrosion casting to assess cochlear vasculature in mouse models of presbycusis and CMV infection

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Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation

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Chemiexcitation: Mammalian Photochemistry in the Dark†

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Lower expression of sialic acid receptors in the cecum of silky fowl (Gallus gallus domesticus Brisson) compared to white leghorn

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Macrophage migration inhibitory factor mediates viability and apoptosis of PVM/Ms through PI3K/Akt pathway

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Cochlin-cleaved LCCL is a dual-armed regulator of the innate immune response in the cochlea during inflammation

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Eye color as a risk factor for acquired sensorineural hearing loss: A review

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A critical evaluation of “leakage” at the cochlear blood-stria-barrier and its functional significance

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Pharmacological Approaches to Hearing Loss

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Thin and open vessel windows for intra-vital fluorescence imaging of murine cochlear blood flow

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Audiovestibular disorders as autoimmune reaction in patients with melanoma

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A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

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Visualization of macrophage subsets in the development of the fetal human inner ear

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Peripheral Auditory Nerve Impairment in a Mouse Model of Syndromic Autism

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Advances and Challenges in Pharmaceutical Therapies to Prevent and Repair Cochlear Injuries From Noise

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Vascular pathology and hearing disorders

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Innate Immunity to Spiral Ganglion Neuron Loss: A Neuroprotective Role of Fractalkine Signaling in Injured Cochlea

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The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

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Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology

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Adenosine improves LPS-induced ROS expression and increasing in monolayer permeability of endothelial cell via acting on A2AR

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CNS macrophage contributions to myelin health

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LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress

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Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system

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Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice

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Protective effect of anakinra on audiovestibular function in a murine model of endolymphatic hydrops

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Mitochondrial Regulation of Macrophages in Innate Immunity and Diverse Roles of Macrophages During Cochlear Inflammation

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Complement factor B is essential for the proper function of the peripheral auditory system

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The Breakdown of Blood‐Labyrinth Barrier Makes it Easier for Drugs to Enter the Inner Ear

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Auditory Phenotype and Histopathologic Findings of a Mutant Nlrp3 Expression Mouse Model

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Molecular mechanisms and roles of inflammatory responses on low-frequency residual hearing after cochlear implantation

Gao, J., & Yi, H. (2021) · Journal of Otology · doi:10.1016/j.joto.2021.03.001 · Cited by 11

Mammalian Inner Ear-Resident Immune Cells—A Scoping Review

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Autoinflammatory characteristics and short-term effects of delivering high-dose steroids to the surface of the intact endolymphatic sac and incus in refractory Ménière's disease

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Towards an Understanding of Microglia and Border-Associated Macrophages

Taketomi, T., & Tsuruta, F. (2023) · Biology · doi:10.3390/biology12081091 · Cited by 12

Sound conditioning strategy promoting paracellular permeability of the blood‐labyrinth‐barrier benefits inner ear drug delivery

Wang, X., Gu, J., Xu, K., Xu, B., Yu, D., & Wu, H. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10596 · Cited by 11

Increased Parenchymal Macrophages are associated with decreased Tyrosine Hydroxylase mRNA levels in the Substantia Nigra of people with Schizophrenia and Bipolar Disorder

Victoriano, G. M., Zhu, Y., Middleton, F. A., Massa, P. T., Ajulu, K., Webster, M. J., & Weickert, C. S. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.116141 · Cited by 11

Distribution of macrophages in the developing cochlea of the common marmoset, a primate model animal

Hosoya, M., Kitama, T., Shimanuki, M. N., Nishiyama, T., Oishi, N., Okano, H., & Ozawa, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1229414 · Cited by 11

Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells

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Melanocytes in black-boned chicken have immune contribution under infectious bursal disease virus infection

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Contribution of circulating monocytes in maintaining homeostasis of resident macrophages in postnatal and young adult mouse cochlea

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Is there a relationship between melanocytes and sensorineural hearing loss? Clinical evaluation of 51 patients with alopecia areata

Koçak, H. E., Acipayam, A. Ş. F., Acıpayam, H., Erdoğan, B. Ç., Yıldız, N., Küfeciler, L., Elbistanlı, M. S., & Kaya, K. H. (2017) · Clinical Otolaryngology · doi:10.1111/coa.13011 · Cited by 9

Melanin in human vestibular organs

Palma, S., Boldrini, P., Nucci, R., Fano, R. A., Cenacchi, G., & Martini, A. (2018) · Hearing Balance and Communication · doi:10.1080/21695717.2018.1461488 · Cited by 9

Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms

Zhang, W., Zheng, J., Meng, J., Neng, L., Chen, X., & Qin, Z. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7684 · Cited by 8

Investigation of intact mouse cochleae using two‐photon laser scanning microscopy

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Molecular differences between young and mature stria vascularis from organotypic explants and transcriptomics

Thulasiram, M. R., Yamamoto, R., Olszewski, R. T., Gu, S., Morell, R. J., Hoa, M., & Dabdoub, A. (2025) · iScience · doi:10.1016/j.isci.2025.111832 · Cited by 7

Three-dimensional mouse cochlea imaging based on the modified Sca/eS using confocal microscopy

Urata, S., & Okabe, S. (2023) · Anatomical Science International · doi:10.1007/s12565-023-00703-z · Cited by 7

Protection of lipopolysaccharide-induced otic injury by a single dose administration of a novel dexamethasone formulation

Murillo‐Cuesta, S., Lara, E., Bermúdez‐Muñoz, J. M., Torres-Campos, E., la Rosa, L. R., López‐Larrubia, P., Erickson, S. R., & Varela‐Nieto, I. (2023) · Translational Medicine Communications · doi:10.1186/s41231-023-00156-6 · Cited by 7

Insights Into Stria Vascular Function, Stria Immunity, and Age-Related Hearing Loss

Shi, X. (2025) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-025-01010-2 · Cited by 6

Engineering vascularized inner ear organoids: Challenges and advances in recapitulating the cochlear microenvironment

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The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea

Rasmussen, J. E., Lundström, P., Eriksson, P. O., Rask‐Andersen, H., Liu, W., & Laurell, G. F. E. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.842132 · Cited by 6

Radiotherapy-associated Sensorineural Hearing Loss in Pediatric Oncology Patients

Aslam, M. A., Ahmad, H., Malik, H. S., Uinarni, H., Karim, Y. S., Akhmedov, Y. M., Abdelbasset, W. K., Awadh, S. A., Abid, M. K., Mustafa, Y. F., et al. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230515112245 · Cited by 8

Cochlear Vascular Pathology and Hearing Loss

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Long non-coding RNA Rian promotes the expression of tight junction proteins in endothelial cells by regulating perivascular-resident macrophage-like melanocytes and PEDF secretion

Zhang, J., Fan, W., Neng, L., Chen, B., Zuo, B., & Lü, W. (2021) · Human Cell · doi:10.1007/s13577-021-00521-3 · Cited by 6

Prevention of aminoglycoside-induced outer hair cell loss by silencing CaMKKβ in an acute mouse model

Wu, F., Xu, S., Su, H., Haque, K., Fang, Q., & Sha, S. (2025) · Hearing Research · doi:10.1016/j.heares.2025.109372 · Cited by 6

Advances in immune mediated inner ear disease

Kullar, P., & Maria, P. L. S. (2025) · Frontiers in Audiology and Otology · doi:10.3389/fauot.2025.1624303 · Cited by 5

Utility of cochlear perilymph biomarkers for hearing loss - A systematic review

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Otologic Manifestations of Psoriasis: A Systematic Review and Meta-Analysis

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Hyaluronic acid-ibuprofen conjugation: a novel ototherapeutic approach protecting inner ear cells from inflammation-mediated damage

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Perivascular macrophage‐like melanocyte responsiveness to acoustic trauma—a salient feature of strial barrier associated hearing loss

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