The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Osmotic pressure inhibition of DNA ejection from phage
Open accessAbstract
Bacterial viral capsids in aqueous solution can be opened in vitro by addition of their specific receptor proteins, with consequent full ejection of their genomes. We demonstrate that it is possible to control the extent of this ejection by varying the external osmotic pressure. In the particular case of bacteriophage λ, the ejection is 50% inhibited by osmotic pressures (of polyethylene glycol) comparable to those operative in the cytoplasm of host bacteria; it is completely suppressed by a pressure of 20 atmospheres. Furthermore, our experiments monitor directly a dramatic decrease of the stress inside the unopened phage capsid upon addition of polyvalent cations to the host solution, in agreement with many recent theories of DNA interactions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Silhavy, T. J., Berman, M. L., & Enquist, L. W. (1984) · Medical Entomology and Zoology · Cited by 2,406
The bacteriophage φ29 portal motor can package DNA against a large internal force
Smith, D. E., Tans, S. J., Smith, S. B., Grimes, S., Anderson, D. L., & Bustamante, C. (2001) · Nature · doi:10.1038/35099581 · Cited by 1,032
[29] Osmotic stress for the direct measurement of intermolecular forces
Parsegian, V. A., Rand, R. P., Fuller, N. L., & Rau, D. C. (1986) · Methods in Enzymology · doi:10.1016/0076-6879(86)27032-9 · Cited by 503
Precipitation of DNA by Polyamines: A Polyelectrolyte Behavior
Raspaud, E., Olvera de la Cruz, M., Sikorav, J.-L., & Livolant, F. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77795-1 · Cited by 441
Self-citationIsolation of the Bacteriophage Lambda Receptor from Escherichia coli
Randall-Hazelbauer, L., & Schwartz, M. (1973) · Journal of Bacteriology · doi:10.1128/jb.116.3.1436-1446.1973 · Cited by 429
DNA packaging and ejection forces in bacteriophage
Kindt, J. T., Tzlil, S., Ben‐Shaul, A., & Gelbart, W. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241486298 · Cited by 360
Self-citationMechanics of DNA packaging in viruses
Purohit, P. K., Kondev, J., & Phillips, R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0737893100 · Cited by 292
Virus-assisted loading of polymer nanocontainer
Graff, A., Sauer, M., Van Gelder, P., & Meier, W. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.062654499 · Cited by 247
Goldschmidt-Clermont, M., & Rahire, M. (1986) · Journal of Molecular Biology · doi:10.1016/0022-2836(86)90137-3 · Cited by 246
Cited by
Horowitz, E. D., Rahman, K. S., Bower, B. D., Dismuke, D. J., Falvo, M. R., Griffith, J. D., Harvey, S. C., & Asokan, A. (2013) · Journal of Virology · doi:10.1128/jvi.03017-12 · Cited by 139
Nucleus size and its effect on nucleosome stability in living cells
Efremov, A. K., Hovan, L., & Yan, J. (2022) · Biophysical Journal · doi:10.1016/j.bpj.2022.09.019 · Cited by 21
Metadata
- Authors
- Evilevitch, A., Lavelle, L., Knobler, C. M., Raspaud, E., & Gelbart, W. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-07-24
- Volume
- 100
- Issue
- 16
- Pages
- 9292-9295
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2103808129
- Cited by
- 334
- References
- 14
- FWCI
- 12.33
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Osmotic pressure inhibition of DNA ejection from phage. https://app.cochat.ai/papers/10.1073/pnas.1233721100
- The paper
- Evilevitch, A., Lavelle, L., Knobler, C. M., Raspaud, E., & Gelbart, W. M. (2003). Osmotic pressure inhibition of DNA ejection from phage. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1233721100
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
