The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
Open accessAbstract
Significance: Human pluripotent stem cells can be cultured in vitro and differentiated into presumably all cell types of the human body, and they therefore represent highly promising cell sources for biomedical applications such as cell therapies, tissue engineering, and drug discovery. These applications require large numbers of high-quality cells, and we report an efficient, defined, scalable, and good manufacturing practice-compatible 3D system for the production of human pluripotent stem cells and their progeny. The ease of use and flexible scalability of this system makes it suitable for numerous applications from the laboratory toward the clinic.
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Cites
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Cited by
Warren, N. J., & Armes, S. P. (2014) · Journal of the American Chemical Society · doi:10.1021/ja502843f · Cited by 1,107
Synthetic alternatives to Matrigel
Aisenbrey, E. A., & Murphy, W. L. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-0199-8 · Cited by 1,016
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Hydrogel scaffolds for tissue engineering: the importance of polymer choice
Spicer, C. D. (2020) · Polymer Chemistry · doi:10.1039/c9py01021a · Cited by 527
Spheroid Culture System Methods and Applications for Mesenchymal Stem Cells
Ryu, N.-E., Lee, S.-H., & Park, H. (2019) · Cells · doi:10.3390/cells8121620 · Cited by 517
Metadata
- Authors
- Lei, Y., & Schaffer, D. V.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2013-11-18
- Volume
- 110
- Issue
- 52
- Pages
- E5039-48
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2149042084
- Cited by
- 332
- References
- 51
- FWCI
- 9.41
- Type
- journal article
- Language
- en
- Open access
- green
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