The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora
Open accessAbstract
Significance: Microbial natural products are a major source of new drug leads, yet discovery efforts are constrained by the lack of information describing the diversity and distributions of the associated biosynthetic pathways among bacteria. Using the marine actinomycete genus Salinispora as a model, we analyzed genome sequence data from 75 closely related strains. The results provide evidence for high levels of pathway diversity, with most being acquired relatively recently in the evolution of the genus. The distributions and evolutionary histories of these pathways provide insight into the mechanisms that generate new chemical diversity and the strategies used by bacteria to maximize their population-level capacity to produce diverse secondary metabolites.
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Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M., & Kumar, S. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr121 · Cited by 39,969
MRBAYES: Bayesian inference of phylogenetic trees.
Huelsenbeck, J. P., & Ronquist, F. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.8.754 · Cited by 21,937
MODELTEST: testing the model of DNA substitution.
Posada, D., & Crandall, K. A. (1998) · Bioinformatics · doi:10.1093/bioinformatics/14.9.817 · Cited by 19,820
Guindon, S., Dufayard, J.-F., Lefort, V., Anisimova, M., Hordijk, W., & Gascuel, O. (2010) · Systematic Biology · doi:10.1093/sysbio/syq010 · Cited by 18,376
Prodigal: prokaryotic gene recognition and translation initiation site identification
Hyatt, D., Chen, G.-L., LoCascio, P. F., Land, M. L., Larimer, F. W., & Hauser, L. J. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-119 · Cited by 12,587
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
Zerbino, D. R., & Birney, E. (2008) · Genome Research · doi:10.1101/gr.074492.107 · Cited by 9,491
(2009) · Cited by 6,571
Gotelli, N. J., & Colwell, R. K. (2001) · Ecology Letters · doi:10.1046/j.1461-0248.2001.00230.x · Cited by 6,420
Consed: A Graphical Tool for Sequence Finishing
Gordon, D., Abajian, C., & Green, P. (1998) · Genome Research · doi:10.1101/gr.8.3.195 · Cited by 3,302
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
Bentley, S. D., Chater, K. F., Cerdeño-Tárraga, A.-M., Challis, G. L., Thomson, N. R., James, K. D., Harris, D. E., Quail, M. A., Kieser, H., Harper, D., et al. (2002) · Nature · doi:10.1038/417141a · Cited by 3,233
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Antibiotics: past, present and future
Hutchings, M. I., Truman, A. W., & Wilkinson, B. (2019) · Current Opinion in Microbiology · doi:10.1016/j.mib.2019.10.008 · Cited by 2,370
Small molecules from the human microbiota
Donia, M. S., & Fischbach, M. A. (2015) · Science · doi:10.1126/science.1254766 · Cited by 760
The evolution of genome mining in microbes – a review
Ziemert, N., Alanjary, M., & Weber, T. (2016) · Natural Product Reports · doi:10.1039/c6np00025h · Cited by 688
Self-citationEcology and genomics of Actinobacteria: new concepts for natural product discovery
van Bergeijk, D. A., Terlouw, B. R., Medema, M. H., & van Wezel, G. P. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0379-y · Cited by 448
Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action
Castro-Falcón, G., Hahn, D., Reimer, D., & Hughes, C. C. (2016) · ACS Chemical Biology · doi:10.1021/acschembio.5b00924 · Cited by 67
Metadata
- Authors
- Ziemert, N., Lechner, A., Wietz, M., Millán-Aguiñaga, N., Chavarria, K. L., & Jensen, P. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-03-10
- Volume
- 111
- Issue
- 12
- Pages
- E1130-9
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1976578940
- Cited by
- 278
- References
- 60
- FWCI
- 19.70
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ziemert, N., Lechner, A., Wietz, M., Millán-Aguiñaga, N., Chavarria, K. L., & Jensen, P. R. (2014). Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1324161111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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