The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Evolutionary shaping of demographic schedules
Abstract
Evolutionary processes of natural selection may be expected to leave their mark on age patterns of survival and reproduction. Demographic theory includes three main strands—mutation accumulation, stochastic vitality, and optimal life histories. This paper reviews the three strands and, concentrating on mutation accumulation, extends a mathematical result with broad implications concerning the effect of interactions between small age-specific effects of deleterious mutant alleles. Empirical data from genomic sequencing along with prospects for combining strands of theory hold hope for future progress.
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Evolutionary theories of senescence including the mutation accumulation theory and age-dependent effects of genetic load offer promising ingredients toward a joint explanation of both the phases of exponential increase and extreme age plateaus.
“Evolutionary theories of senescence including the mutation accumulation theory and age-dependent effects of genetic load (25) also offer promising ingredients toward a joint explanation of both the phases of exponential increase and extreme age plateaus.”
From The plateau of human mortality: Demography of longevity pioneers (2018) · cites this paper as [25]
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Cites
Rate of de novo mutations and the importance of father’s age to disease risk
Kong, A., Frigge, M. L., Masson, G., Besenbacher, S., Sulem, P., Magnusson, G., Gudjonsson, S. A., Sigurdsson, A., Jonasdottir, A., Jonasdottir, A., et al. (2012) · Nature · doi:10.1038/nature11396 · Cited by 2,134
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
Tennessen, J. A., Bigham, A. W., O’Connor, T. D., Fu, W., Kenny, E. E., Gravel, S., McGee, S., Do, R., Liu, X., Jun, G., et al. (2012) · Science · doi:10.1126/science.1219240 · Cited by 1,613
The deleterious mutation load is insensitive to recent population history.
Simons, Y. B., Turchin, M. C., Pritchard, J. K., & Sella, G. (2014) · Nature Genetics · doi:10.1038/ng.2896 · Cited by 279
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The plateau of human mortality: Demography of longevity pioneers
Barbi, E., Lagona, F., Marsili, M., Vaupel, J. W., & Wachter, K. W. (2018) · Science · doi:10.1126/science.aat3119 · Cited by 299
Self-citationThe emergence of longevous populations
Colchero, F., Rau, R., Jones, O. R., Barthold, J. A., Conde, D. A., Lenart, A., Nemeth, L., Scheuerlein, A., Schoeley, J., Torres, C., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1612191113 · Cited by 182
Metadata
- Authors
- Wachter, K. W., Steinsaltz, D., & Evans, S. N.
- Affiliations
- Departments of aDemography,
- Department of Statistics, Oxford University, Oxford OX1 3TG, England
- Statistics, and
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-07-14
- Volume
- 111
- Issue
- supplement_3
- Pages
- 10846-10853
- ISSN
- 0027-8424
- 1091-6490
- Cited by
- 36
- References
- 3
- Language
- en
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