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Biodemography of human ageing

Vaupel, James W.·2010·Nature
DOI 10.1038/nature08984PMC PMC4010874
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Crossref · 10.1038/nature08984

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3 of 3 references verified0 citation errors · 0 not checkable

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  • These well-estimated hazard curves share the qualitative pattern observed at extreme ages in widely differing species.

    “Thus these well-estimated hazard curves share the qualitative pattern observed at extreme ages in widely differing species (8, 18)”

    From The plateau of human mortality: Demography of longevity pioneers (2018) · cites this paper as [18]

    In “Delay not deceleration,” the paper reports a constant annual probability of death at validated human ages 110–114. Its discussion of other species describes varied age-related mortality patterns, and its References list a study of slowing mortality in medflies; it does not establish that well-estimated hazard curves share the same extreme-age pattern across widely differing species. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

  • Demographic evidence has revealed an ongoing reduction in old-age mortality and a rise of the maximum age at death, which may gradually extend human longevity.

    “Demographic evidence has revealed an ongoing reduction in old-age mortality and a rise of the maximum age at death, which may gradually extend human longevity1,2.”

    From Evidence for a limit to human lifespan (2016) · cites this paper as [2]

    In ‘The postponement of mortality’ (page unavailable), the paper says mortality at advanced ages is being postponed and challenges the idea of a fixed maximum lifespan. ‘Forecasts and consequences of longer lives’ documents rising life expectancy. Our copy does not establish the more specific claim that the maximum observed age at death has risen. (LLM, conf=0.83)

    Experimental — accuracy not yet measured

  • The most convincing argument that the maximum lifespan of humans is not fixed is the ongoing increase in life expectancy in most countries over the last century.

    “Indeed, the most convincing argument that the maximum lifespan of humans is not fixed is the ongoing increase in life expectancy in most countries over the course of the last century1,2.”

    From Evidence for a limit to human lifespan (2016) · cites this paper as [2]

    In “The postponement of mortality” (page not provided), Vaupel says that mortality at advanced ages is being postponed and that the notion of a species-specific maximum lifespan was refuted. “Forecasts and consequences of longer lives” reports a sustained rise in life expectancy over 170 years, but for countries with the highest life expectancies—not most countries. The paper also does not identify that trend as the most convincing argument against a fixed maximum lifespan. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • The fixed-frailty proportional hazard model of Vaupel, Stallard, and Manton implies approach to plateaus.

    “The fixed-frailty proportional hazard model of Vaupel, Stallard, and Manton (19) (with precursor 20) implies approach to plateaus (5, 8, 18)”

    From The plateau of human mortality: Demography of longevity pioneers (2018) · cites this paper as [18]

    The References section lists Vaupel, Manton, and Stallard’s work on individual frailty and separately lists work on mortality-rate deceleration, but does not say that a fixed-frailty proportional-hazard model implies an approach to plateaus. Searches for plateaus, proportional hazards, frailty, and mortality deceleration found no passage in our copy establishing that implication. (LLM, conf=0.72)

    Experimental — accuracy not yet measured

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Citations

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Research works printed but not linked: 97

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Metadata

Authors
Vaupel, J. W.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2010-03
Volume
464
Issue
7288
Pages
536-542
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/nature08984
PMC
PMC4010874
Cited by
863
References
3
Language
en
Licence
www.springer.com/tdm (tdm)

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