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Biodemographic Trajectories of Longevity
Abstract
Old-age survival has increased substantially since 1950. Death rates decelerate with age for insects, worms, and yeast, as well as humans. This evidence of extended postreproductive survival is puzzling. Three biodemographic insights—concerning the correlation of death rates across age, individual differences in survival chances, and induced alterations in age patterns of fertility and mortality—offer clues and suggest research on the failure of complicated systems, on new demographic equations for evolutionary theory, and on fertility-longevity interactions. Nongenetic changes account for increases in human life-spans to date. Explication of these causes and the genetic license for extended survival, as well as discovery of genes and other survival attributes affecting longevity, will lead to even longer lives.
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These well-estimated hazard curves share the qualitative pattern observed at extreme ages in widely differing species.
“Thus these well-estimated hazard curves share the qualitative pattern observed at extreme ages in widely differing species (8, 18)”
From The plateau of human mortality: Demography of longevity pioneers (2018) · cites this paper as [8]
The fixed-frailty proportional hazard model of Vaupel, Stallard, and Manton implies approach to plateaus.
“The fixed-frailty proportional hazard model of Vaupel, Stallard, and Manton (19) (with precursor 20) implies approach to plateaus (5, 8, 18)”
From The plateau of human mortality: Demography of longevity pioneers (2018) · cites this paper as [8]
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Metadata
- Authors
- Vaupel, J. W., Carey, J. R., Christensen, K., Johnson, T. E., Yashin, A. I., Holm, N. V., Iachine, I. A., Kannisto, V., Khazaeli, A. A., Liedo, P., Longo, V. D., Zeng, Y., Manton, K. G., & Curtsinger, J. W.
- Affiliations
- J. W. Vaupel is at the Max Planck Institute for Demographic Research, D-18057 Rostock, Germany; Odense University Medical School, DK-5000 Odense C, Denmark; the Center for Demographic Studies, Duke University, Durham, NC 27706, USA; and Andrus Gerontology Center, the University of Southern California, Los Angeles, CA 90089–0191, USA. J. R. Carey is in the Department of Entomology, University of California at Davis, Davis, CA 95616–8584, USA. K. Christensen, N. V. Holm, I. A. Iachine, and V. Kannisto...
- Venue
- Science
- Published
- 1998-05-08
- Volume
- 280
- Issue
- 5365
- Pages
- 855-860
- ISSN
- 0036-8075
- 1095-9203
- Cited by
- 803
- References
- 2
- Language
- en
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