The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Commensal bacteria protect against food allergen sensitization
Open accessAbstract
Significance: The prevalence of food allergy is rising at an alarming rate; the US Centers for Disease Control and Prevention documented an 18% increase among children in the United States between 1997 and 2007. Twenty-first century environmental interventions are implicated by this dramatic generational increase. In this report we examine how alterations in the trillions of commensal bacteria that normally populate the gastrointestinal tract influence allergic responses to food. We identify a bacterial community that protects against sensitization and describe the mechanism by which these bacteria regulate epithelial permeability to food allergens. Our data support the development of novel adjunctive probiotic therapies to potentiate the induction of tolerance to dietary allergens.
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Citations
Cites
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
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The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
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BackgroundInnate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
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Cited by
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C. R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y. (2015) · Cell · doi:10.1016/j.cell.2015.02.047 · Cited by 3,614
Self-citationThe microbiome and innate immunity
Thaiss, C. A., Zmora, N., Levy, M., & Elinav, E. (2016) · Nature · doi:10.1038/nature18847 · Cited by 2,012
The microbiota in adaptive immune homeostasis and disease
Honda, K., & Littman, D. R. (2016) · Nature · doi:10.1038/nature18848 · Cited by 1,846
Health benefits of fermented foods: Microbiota and beyond
Marco, M. L., Heeney, D., Binda, S., Cifelli, C. J., Cotter, P. D., Foligné, B., Gänzle, M., Kort, R., Pasin, G., Pihlanto, A., et al. (2017) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2016.11.010 · Cited by 1,674
Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans
Vatanen, T., Kostic, A. D., d’Hennezel, E., Siljander, H., Franzosa, E. A., Yassour, M., Kolde, R., Vlamakis, H., Arthur, T. D., Hämäläinen, A.-M., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.007 · Cited by 1,289
Metadata
- Authors
- Stefka, A. T., Feehley, T., Tripathi, P., Qiu, J., McCoy, K., Mazmanian, S. K., Tjota, M. Y., Seo, G.-Y., Cao, S., Theriault, B. R., Antonopoulos, D. A., Zhou, L., Chang, E. B., Fu, Y.-X., & Nagler, C. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-08-25
- Volume
- 111
- Issue
- 36
- Pages
- 13145-13150
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2155825126
- Cited by
- 795
- References
- 9
- FWCI
- 45.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Commensal bacteria protect against food allergen sensitization. https://app.cochat.ai/papers/10.1073/pnas.1412008111
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- Stefka, A. T., Feehley, T., Tripathi, P., Qiu, J., McCoy, K., Mazmanian, S. K., Tjota, M. Y., Seo, G.-Y., Cao, S., Theriault, B. R., Antonopoulos, D. A., Zhou, L., Chang, E. B., Fu, Y.-X., & Nagler, C. R. (2014). Commensal bacteria protect against food allergen sensitization. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1412008111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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