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Cited by 490

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Cell separation using tilted-angle standing surface acoustic waves

Open access
Ding, Xiaoyun, Peng, Zhangli, Lin, Sz-Chin Steven, Geri, Michela, Li, Sixing, Li, Peng, Chen, Yuchao, Dao, Ming, Suresh, Subra, Huang, Tony Jun·2014·Proceedings of the National Academy of Sciences

Abstract

Significance: We have developed a unique approach for the separation of particles and biological cells through standing surface acoustic waves oriented at an optimum angle to the fluid flow direction in a microfluidic device. This experimental setup, optimized by systematic analyses, has been used to demonstrate effective separation based on size, compressibility, and mechanical properties of particles and cells. The potential of this method for biological–biomedical applications was demonstrated through the example of isolating MCF-7 breast cancer cells from white blood cells. The method offers a possible route for label-free particle or cell separation for many applications in research, disease diagnosis, and drug-efficacy assessment.

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Crossref · 10.1073/pnas.1413325111

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Metadata

Authors
Ding, X., Peng, Z., Lin, S.-C. S., Geri, M., Li, S., Li, P., Chen, Y., Dao, M., Suresh, S., & Huang, T. J.
Venue
Proceedings of the National Academy of Sciences
Published
2014-08-25
Volume
111
Issue
36
Pages
12992-12997
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2007700456
Cited by
490
References
2
FWCI
22.84
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Cell separation using tilted-angle standing surface acoustic waves. https://app.cochat.ai/papers/10.1073/pnas.1413325111
The paper
Ding, X., Peng, Z., Lin, S.-C. S., Geri, M., Li, S., Li, P., Chen, Y., Dao, M., Suresh, S., & Huang, T. J. (2014). Cell separation using tilted-angle standing surface acoustic waves. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1413325111

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