The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth
Open accessAbstract
Significance: Obesity and metabolic syndrome may, in part, originate in fetal life. In particular, babies of mothers with obesity and/or gestational diabetes mellitus (GDM) are often large at birth and have increased adiposity, which predisposes them to the development of metabolic disease later in life. Maternal obesity and GDM are typically associated with low circulating levels of adiponectin (ADN), and we found that ADN supplementation to pregnant obese mice completely normalized the changes in placental function and prevented fetal overgrowth caused by maternal obesity. These findings suggest that strategies to increase ADN levels in maternal obesity and GDM may alleviate the adverse effects of these pregnancy complications on the fetus.
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A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
Okada-Iwabu, M., Yamauchi, T., Iwabu, M., Honma, T., Hamagami, K.-I., Matsuda, K., Yamaguchi, M., Tanabe, H., Kimura-Someya, T., Shirouzu, M., et al. (2013) · Nature · doi:10.1038/nature12656 · Cited by 757
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Self-citationRosario, F. J., Kanai, Y., Powell, T. L., & Jansson, T. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.238014 · Cited by 185
Self-citationJones, H. N., Jansson, T., & Powell, T. L. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00195.2009 · Cited by 168 · cited 1×
“SNAT2 represents a highly regulated system A isoform in the placenta (25, 35, 36) and in other tissues (37).”
BackgroundSelf-citationThe Role of Placental Nutrient Sensing in Maternal-Fetal Resource Allocation1
Díaz, P., Powell, T. L., & Jansson, T. (2014) · Biology of Reproduction · doi:10.1095/biolreprod.114.121798 · Cited by 158
Self-citationPlacental transport in response to altered maternal nutrition
Gaccioli, F., Lager, S., Powell, T. L., & Jansson, T. (2013) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000529 · Cited by 129 · cited 1×
“Changes in placental nutrient transport alter nutrient flux to the fetus and, ultimately, fetal growth, independent of maternal nutrient levels (30, 31).”
BackgroundSelf-citationRosario, F. J., Kanai, Y., Powell, T. L., & Jansson, T. (2015) · Obesity · doi:10.1002/oby.21165 · Cited by 128
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Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring
Buffington, S. A., Di Prisco, G. V., Auchtung, T. A., Ajami, N. J., Petrosino, J. F., & Costa-Mattioli, M. (2016) · Cell · doi:10.1016/j.cell.2016.06.001 · Cited by 1,163
The endocrine function of adipose tissues in health and cardiometabolic disease
Scheja, L., & Heeren, J. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0230-6 · Cited by 663
Developmental origins of metabolic diseases
Hoffman, D. J., Powell, T. L., Barrett, E. S., & Hardy, D. B. (2021) · Physiological Reviews · doi:10.1152/physrev.00002.2020 · Cited by 466
Self-citationPlacental Responses to Changes in the Maternal Environment Determine Fetal Growth
Dimasuay, K. G., Boeuf, P., Powell, T. L., & Jansson, T. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00012 · Cited by 258
Self-citationPlacental Function in Maternal Obesity
Kelly, A. C., Powell, T. L., & Jansson, T. (2020) · Clinical Science · doi:10.1042/cs20190266 · Cited by 227
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Metadata
- Authors
- Aye, I. L. M. H., Rosario, F. J., Powell, T. L., & Jansson, T.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2015-09-28
- Volume
- 112
- Issue
- 41
- Pages
- 12858-12863
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2129993215
- Cited by
- 160
- References
- 12
- FWCI
- 12.55
- Type
- journal article
- Language
- en
- Open access
- green
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- Aye, I. L. M. H., Rosario, F. J., Powell, T. L., & Jansson, T. (2015). Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1515484112
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