Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., et al. (2012) · Cell · doi:10.1016/j.cell.2012.03.042 · Cited by 18,691

Regulation of Ferroptotic Cancer Cell Death by GPX4

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Principles of bioactive lipid signalling: lessons from sphingolipids

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Ferroptosis as a p53-mediated activity during tumour suppression

Jiang, L., Kon, N., Li, T., Wang, S.-J., Su, T., Hibshoosh, H., Baer, R., & Gu, W. (2015) · Nature · doi:10.1038/nature14344 · Cited by 3,398

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

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Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

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A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

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RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

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Lentivirus-delivered stable gene silencing by RNAi in primary cells.

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Punicic Acid Triggers Ferroptotic Cell Death in Carcinoma Cells

Vermonden, P., Vancoppenolle, M., Dierge, E., Mignolet, É., Cuvelier, G., Knoops, B., Page, M. M., Debier, C., Féron, O., & Larondelle, Y. (2021) · Nutrients · doi:10.3390/nu13082751 · Cited by 56

Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation

Qin, Y., Pei, Z., Feng, Z., Lin, P., Wang, S., Li, Y. H., Huo, F., Wang, Q., Wang, Z., Chen, Z., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.751593 · Cited by 52

Inherent preference for polyunsaturated fatty acids instigates ferroptosis of Treg cells that aggravates high-fat-diet-related colitis

Yan, J., Zeng, Y., Guan, Z., Li, Z., Luo, S., Niu, J., Zhao, J., Gong, H., Huang, T., Li, Z., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114636 · Cited by 54

Fatty Acid Metabolism Reprogramming in Advanced Prostate Cancer

Xu, H., Chen, Y., Gu, M., Liu, C., Chen, Q., Zhan, M., & Wang, Z. (2021) · Metabolites · doi:10.3390/metabo11110765 · Cited by 52

Ferroptosis of Endothelial Cells in Vascular Diseases

Zhang, H., Zhou, S., Sun, M., Hua, M., Liu, Z., Mu, G., Wang, Z., Xiang, Q., & Cui, Y. (2022) · Nutrients · doi:10.3390/nu14214506 · Cited by 50

Insight into the potential role of ferroptosis in neurodegenerative diseases

Ji, Y., Zheng, K., Li, S., Ren, C., Shen, Y., Tian, L., Zhu, H., Zhou, Z., & Jiang, Y. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1005182 · Cited by 53

Theaflavin‐3,3′‐Digallate Inhibits Erastin‐Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis

Xu, C., Ni, S., Xu, N., Yin, G., Yu, Y., Zhou, B., Zhao, G., Wang, L., Zhu, R., Jiang, S., et al. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3531995 · Cited by 50

Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis

Lv, Y., Chen, D., Tian, X., Xiao, J., Xu, C., Du, L., Li, J., Zhou, S., Chen, Y., Zhuang, R., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04111-9 · Cited by 52

Fe/Al‐LDH Nanomedicine for Antitumor Ferroptosis‐Immunotherapy by Immunosuppression Reversal

Fang, W., Yu, Z., Hu, P., & Shi, J. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202405483 · Cited by 50

Ferroptosis and myocardial ischemia-reperfusion: mechanistic insights and new therapeutic perspectives

Jin, B., Zhang, Z., Zhang, Y., Yang, M., Wang, C., Xu, J., Zhu, Y., Mi, Y., Jiang, J., & Sun, Z. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1482986 · Cited by 56

Targeting Ferroptosis in Parkinson’s Disease: Mechanisms and Emerging Therapeutic Strategies

Zhou, M., Xu, K., Ge, J., Luo, X., Wu, M., Wang, N., & Zeng, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252313042 · Cited by 58

Iron homeostasis and ferroptosis in muscle diseases and disorders: mechanisms and therapeutic prospects

Ru, Q., Li, Y., Zhang, F., Chen, L., Wu, Y., Min, J., & Wang, F. (2025) · Bone Research · doi:10.1038/s41413-024-00398-6 · Cited by 62

Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway

Liu, C., Li, H.-H., Lin, J.-H., Chiang, M., Hsu, T.-W., Li, A. F., Yen, D. H.-T., Hsu, H., & Hung, S. (2021) · Biomolecules · doi:10.3390/biom12010048 · Cited by 49

Lipid metabolism alterations and ferroptosis in cancer: Paving the way for solving cancer resistance

Lee, J., Shin, D., & Roh, J. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175497 · Cited by 50

Mechanism of Ferroptosis and Its Role in Spinal Cord Injury

Li, F., Wang, H., Chen, H., Guo, J., Dang, X., Ru, Y., & Wang, H. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.926780 · Cited by 50

Sodium selenite promotes neurological function recovery after spinal cord injury by inhibiting ferroptosis

Gao, F., Li, J., Chen, Y., Talifu, Z., Liu, B., Guo, S., Yang, D., Yu, Y., Yang, M., & Du, L. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.339491 · Cited by 49

The Role of Iron Metabolism, Lipid Metabolism, and Redox Homeostasis in Alzheimer’s Disease: from the Perspective of Ferroptosis

Wu, L., Xian, X., Tan, Z., Dong, F., Xu, G., Zhang, M., & Zhang, F. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03245-7 · Cited by 51

Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

Amos, A., Jiang, N., Zong, D., Gu, J., Zhou, J., Li, Y., He, X., Xu, Y., & Wu, L. (2023) · BMC Cancer · doi:10.1186/s12885-022-10465-y · Cited by 52

Fatty acids in cancer: Metabolic functions and potential treatment

Du, A., Wang, Z., Huang, T., Xue, S., Jiang, C., Qiu, G., & Yuan, K. (2023) · MedComm – Oncology · doi:10.1002/mog2.25 · Cited by 55

Mitochondria-derived methylmalonic acid aggravates ischemia–reperfusion injury by activating reactive oxygen species-dependent ferroptosis

Guo, J., Wang, S., Wan, X. H., Liu, X., Wang, Z., Liang, C., Zhang, Z., Wang, Y., Yan, M., Wu, P., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01479-z · Cited by 51

Metal-phenolic nanocatalyst rewires metabolic vulnerability for catalytically amplified ferroptosis

Zhu, Y., Niu, X., Wu, T., Cheng, J., Zou, J., Pan, Y., Tian, Y. Q., Huang, W., Ding, C., Lin, Y., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.150126 · Cited by 48

Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines

Lai, W., Wang, B., Huang, R., Zhang, C., Fu, P., & Ma, L. (2024) · Journal of Translational Internal Medicine · doi:10.2478/jtim-2023-0137 · Cited by 50

Nrf2-mediated ferroptosis inhibition: a novel approach for managing inflammatory diseases

Han, H., Zhang, G., Zhang, X., & Zhao, Q. (2024) · Inflammopharmacology · doi:10.1007/s10787-024-01519-7 · Cited by 56

The solute carrier transporters (SLCs) family in nutrient metabolism and ferroptosis

Sun, L., He, H.-Y., Li, W., Jin, W., & Wei, Y. (2024) · Biomarker Research · doi:10.1186/s40364-024-00645-2 · Cited by 49

Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease

Sidhom, E.-H., Kim, C., Kost‐Alimova, M., Ting, M. T., Keller, K. H., Ávila-Pacheco, J., Watts, A. J. B., Vernon, K. A., Marshall, J. L., Bricio, E. R., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci141380 · Cited by 48

A New Ferroptosis-Related lncRNA Signature Predicts the Prognosis of Bladder Cancer Patients

Chen, M., Nie, Z., Li, Y., Gao, Y., Wen, X., Cao, H., & Zhang, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.699804 · Cited by 47

Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications

Mao, X., Wang, X., Jin, M., Li, Q., Jia, J.-N., Li, M., Zhou, H., Liu, Z., Jin, W., Zhao, Y., et al. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.04.017 · Cited by 47

Mitochondrial Reactive Oxygen Species and Lytic Programmed Cell Death in Acute Inflammation

Rius‐Pérez, S., Pérez, S., Tolédano, M. B., & Sastre, J. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0209 · Cited by 48

Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury

Lin, H., Ma, C., Zhuang, X., Liu, S., Liu, D., Zhang, M., Lu, Y., Zhou, G., Zhang, C., Wang, T., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.09.007 · Cited by 47

Exploiting metabolic cell death for cancer therapy

Mao, C., Jiang, D., Koong, A. C., & Gan, B. (2025) · Nature reviews. Cancer · doi:10.1038/s41568-025-00879-8 · Cited by 70

iTRAQ-based quantitative proteomics analysis of the spleen reveals innate immunity and cell death pathways associated with heat stress in broilers (Gallus gallus)

Ma, D., Liu, Q., Zhang, M., Feng, J., Li, X., Zhou, Y. Q., & Wang, X. (2019) · Journal of Proteomics · doi:10.1016/j.jprot.2019.01.012 · Cited by 48

Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells

Kathman, S. G., Boshart, J., Jing, H., & Cravatt, B. F. (2020) · ACS Chemical Biology · doi:10.1021/acschembio.0c00086 · Cited by 47

Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma

Wang, Y., Qiu, S., Wang, H., Cui, J., Tian, X., Miao, Y., Zhang, C., Cao, L., Ma, L., Xu, X., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.719187 · Cited by 48

Systems biology of ferroptosis: A modeling approach

Konstorum, A., Tesfay, L., Paul, B. T., Torti, F. M., Laubenbacher, R., & Torti, S. V. (2020) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2020.110222 · Cited by 45

Inducing ferroptosis has the potential to overcome therapy resistance in breast cancer

Qi, X., Wan, Z., Jiang, B., Ouyang, Y., Feng, W., Zhu, H., Tan, Y., He, R., Xie, L., & Li, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1038225 · Cited by 50

Metal-free polymer nano-photosensitizer actuates ferroptosis in starved cancer

Chen, D., Liang, C., Qu, X., Zhang, T., Mou, X., Cai, Y., Wang, W., Shao, J., & Dong, X. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121944 · Cited by 47

Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3–NFS1 axis in doxorubicin-induced cardiotoxicity

Wang, Y., Ying, X., Wang, Y., Zou, Z., Yuan, A., Xiao, Z., Geng, N., Qiao, Z., Li, W., Lu, X., et al. (2023) · Cellular Signalling · doi:10.1016/j.cellsig.2023.110655 · Cited by 46

Ferroptosis in gastrointestinal cancer: from mechanisms to implications

Zhang, R., Kang, R., & Tang, D. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216147 · Cited by 46

Regulated necrosis role in inflammation and repair in acute kidney injury

Guerrero‐Mauvecin, J., Villar-Gómez, N., Rayego‐Mateos, S., Ramos, A. M., Ruiz‐Ortega, M., Ortíz, A., & Sanz, A. B. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1324996 · Cited by 52

Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression

Zhou, Y., Nakajima, R., Shirasawa, M., Fikriyanti, M., Zhao, L., Iwanaga, R., Bradford, A. P., Kurayoshi, K., Araki, K., & Ohtani, K. (2023) · Biology · doi:10.3390/biology12121511 · Cited by 52

Baicalein improves the symptoms of polycystic ovary syndrome by mitigating oxidative stress and ferroptosis in the ovary and gravid placenta

Li, Y., Peng, Y., Yang, Y., Shi, T., Liu, R., Luan, Y., & Yin, C. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155423 · Cited by 46

Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction

Chamoli, M., Goyala, A., Tabrez, S. S., Siddiqui, A. A., Singh, A., Antebi, A., Lithgow, G. J., Watts, J. L., & Mukhopadhyay, A. (2020) · Nature Communications · doi:10.1038/s41467-020-18690-4 · Cited by 47

Ferroptosis in Friedreich’s Ataxia: A Metal-Induced Neurodegenerative Disease

Rosa, P. L., Petrillo, S., Fiorenza, M. T., Bertini, E., & Piemonte, F. (2020) · Biomolecules · doi:10.3390/biom10111551 · Cited by 49

Correlation of Ferroptosis and Other Types of Cell Death in Neurodegenerative Diseases

Dang, X., Huan, X., Du, X., Chen, X., Bi, M., Yan, C., Jiao, Q., & Jiang, H. F. (2022) · Neuroscience Bulletin · doi:10.1007/s12264-022-00861-6 · Cited by 46

PCSK9: A emerging participant in heart failure

Xu, Q., Zhao, Y.-M., He, N.-Q., Gao, R., Xu, W., Zhuo, X.-J., Ren, Z., Wu, C., & Liu, L. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114106 · Cited by 47

Ferroptosis: mechanisms and advances in ocular diseases

Liu, K., Li, H., Wang, F., & Su, Y. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04644-5 · Cited by 47

Role of ferroptosis in pregnancy related diseases and its therapeutic potential

Xu, J., Zhou, F., Wang, X., & Mo, C. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1083838 · Cited by 45

Ferroptosis, necroptosis and cuproptosis: Novel forms of regulated cell death in diabetic cardiomyopathy

Ke, D., Zhang, Z., Liu, J., Chen, P., Li, J., Sun, X., Chu, Y., & Li, L. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1135723 · Cited by 45

Research progress in the molecular mechanism of ferroptosis in Parkinson's disease and regulation by natural plant products

Yang, K., Zeng, L., Zeng, J., Deng, Y., Wang, S., Xu, H., He, Q., Yuan, M., Luo, Y., Ge, A., et al. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102063 · Cited by 46

Targeting programmed cell death in diabetic kidney disease: from molecular mechanisms to pharmacotherapy

Liu, F., Yang, Z., Li, J., Wu, T., Li, X., Zhao, L., Wang, W., Yu, W., Zhang, G., & Xu, Y. (2024) · Molecular Medicine · doi:10.1186/s10020-024-01020-5 · Cited by 51

Selenium-Dependent Glutathione Peroxidases During Tumor Development

Kipp, A. P. (2017) · Advances in cancer research · doi:10.1016/bs.acr.2017.07.004 · Cited by 47

The Role of Ferroptosis in Adverse Left Ventricular Remodeling Following Acute Myocardial Infarction

Komai, K., Kawasaki, N. K., Higa, J. K., & Matsui, T. (2022) · Cells · doi:10.3390/cells11091399 · Cited by 48

Localized disruption of redox homeostasis boosting ferroptosis of tumor by hydrogel delivery system

Su, X., Cao, Y., Liu, Y., Ouyang, B., Ning, B., Wang, Y., Guo, H., Pang, Z., & Shen, S. (2021) · Materials Today Bio · doi:10.1016/j.mtbio.2021.100154 · Cited by 44

Ferroptosis and Its Emerging Role in Pre-Eclampsia

Chen, Z., Gan, J., Zhang, M., Du, Y., & Zhao, H. (2022) · Antioxidants · doi:10.3390/antiox11071282 · Cited by 46

Research Progress of Ferroptosis Regulatory Network and Bone Remodeling in Osteoporosis

Yan, C., Zhang, J., An, F., Wang, J., Shi, Y., Yuan, L., Lv, D., Zhao, Y., & Wang, Y. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.910675 · Cited by 49

GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide

Parik, S., Fernández-García, J., Lodi, F., Vlaminck, K. D., Derweduwe, M., Vleeschouwer, S. D., Sciot, R., Geens, W., Weng, L., Bosisio, F. M., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.988872 · Cited by 43

Directly imaging emergence of phase separation in peroxidized lipid membranes

Páez-Pérez, M., Vyšniauskas, A., López‐Duarte, I., Lafarge, E., de Castro, R. L.-R., Marques, C. M., Schröder, A., Muller, P., Lorenz, C. D., Brooks, N. J., et al. (2023) · Communications Chemistry · doi:10.1038/s42004-022-00809-x · Cited by 44

Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance

Wu, T., Wan, J., Qu, X., Xia, K., Wang, F., Zhang, Z., Yang, M., Wu, X., Gao, R., Yuan, X., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05756-6 · Cited by 44

Impact of ferroptosis on preeclampsia: A review

Shan, Y., Guan, C., Wang, J., Qi, W., Chen, A., & Liu, S. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115466 · Cited by 47

Iron metabolism and ferroptosis: A pathway for understanding preeclampsia

Gumilar, K. E., Priangga, B., Lu, C., Dachlan, E. G., & Tan, M. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115565 · Cited by 46

PUFAs add fuel to Crohn’s disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation

Wen, W., Xu, Y., Qian, W., Huang, L., Gong, J., Li, Y. Z., Zhu, W., & Guo, Z. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2265578 · Cited by 44

Broadening horizons: ferroptosis as a new target for traumatic brain injury

Wei, Z., Yu, H., Zhao, H., Wei, M., Xing, H., Pei, J., Yang, Y., & Ren, K. (2023) · Burns & Trauma · doi:10.1093/burnst/tkad051 · Cited by 53

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer’s disease

Shen, Y., Zhang, G., Wei, C., Zhao, P., Wang, Y., Li, M., & Sun, L. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01343 · Cited by 44

Mifepristone protects acetaminophen induced liver injury through NRF2/GSH/GST mediated ferroptosis suppression

Shi, Y., Xu, N., Liu, B., Ma, Y., Fu, X., Shang, Y., Huang, Q., Yao, Q., Chen, J., & Li, H. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.06.014 · Cited by 44

Ferroptosis Mechanisms Involved in Hippocampal-Related Diseases

Wang, X., Wang, Z., Cao, J., Dong, Y., & Chen, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189902 · Cited by 43

The potential applications of traditional Chinese medicine in Parkinson's disease: A new opportunity

Chen, J., Xu, J., Huang, P., Luo, Y., Shi, Y., & Ma, P. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112866 · Cited by 46

Molecular mechanisms of ferroptosis and its role in prostate cancer therapy

Wang, S., Wei, W., Ma, N., Qu, Y., & Liu, Q. (2022) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2022.103732 · Cited by 44

Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion

Vučković, A., Venerando, R., Tibaldi, E. V., Bosello-Travain, V., Roveri, A., Bordin, L., Miotto, G., Cozza, G., Toppo, S., Maiorino, M., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.02.045 · Cited by 44

The Molecular Mechanisms of Ferroptosis and Its Role in Blood-Brain Barrier Dysfunction

Chen, X., Pang, X., Yeo, A. J., Xie, S., Xiang, M., Shi, B., Yu, G., & Li, C. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.889765 · Cited by 46

Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE

Li, W., Luo, L., Zhou, Q., Gong, H., Fu, Y., Yan, C., Li, E., Sun, J. Y., Luo, Z., Ding, Z., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102421 · Cited by 44

Role Of YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer

Zhou, W., Lim, A., Edderkaoui, M., Osipov, A., Wu, H., Wang, Q., & Pandol, S. J. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.83586 · Cited by 49

Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancer

Herrera-Abreu, M. T., Guan, J., Khalid, U., Ning, J., Costa, M. R., Chan, J., Li, Q., Fortin, J., Wong, W., Perampalam, P., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53837-7 · Cited by 51

The clinical relevance of necroinflammation—highlighting the importance of acute kidney injury and the adrenal glands

Tonnus, W., Gembardt, F., Latk, M., Parmentier, S. P., Hugo, C., Bornstein, S. R., & Linkermann, A. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-018-0193-5 · Cited by 44

Inhibiting ACSL1-Related Ferroptosis Restrains Murine Coronavirus Infection

Xia, H., Zhang, Z., & You, F. (2021) · Viruses · doi:10.3390/v13122383 · Cited by 45

Ferroptosis, novel therapeutics in asthma

Lv, X., Dong, M., Tang, W., Qin, J., Wang, W., Li, M., Teng, F., Yi, L., Dong, J., & Wei, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113516 · Cited by 43

Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis

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Effect of regulatory cell death on the occurrence and development of head and neck squamous cell carcinoma

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