Oriented collagen fibers direct tumor cell intravasation

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323

Hydrogels for tissue engineering: scaffold design variables and applications

Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Provenzano, P. P., Eliceiri, K. W., Campbell, J. M., Inman, D. R., White, J. G., & Keely, P. J. (2006) · BMC Medicine · doi:10.1186/1741-7015-4-38 · Cited by 1,804

Collagen density promotes mammary tumor initiation and progression

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,394

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Conklin, M. W., Eickhoff, J. C., Riching, K. M., Pehlke, C. A., Eliceiri, K. W., Provenzano, P. P., Friedl, A., & Keely, P. J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.11.076 · Cited by 1,321

Mechanical properties of hydrogels and their experimental determination

Anseth, K. S., Bowman, C. N., & Brannon-Peppas, L. (1996) · Biomaterials · doi:10.1016/0142-9612(96)87644-7 · Cited by 1,156

Effects of radiation on normal tissue: consequences and mechanisms

Stone, H. B., Coleman, C. N., Anscher, M. S., & McBride, W. H. (2003) · The Lancet Oncology · doi:10.1016/s1470-2045(03)01191-4 · Cited by 934

β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy

Soto, C. A., Sigurdsson, E. M., Morelli, L., Kumar, R., Castaño, E. M., & Frangione, B. (1998) · Nature Medicine · doi:10.1038/nm0798-822 · Cited by 874

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

Zervantonakis, I. K., Hughes-Alford, S. K., Charest, J. L., Condeelis, J. S., Gertler, F. B., & Kamm, R. D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210182109 · Cited by 872

Association of the collagen signature with pathological complete response in rectal cancer patients

Jiang, W., Wang, S., Wan, J., Zheng, J., Dong, X., Liu, Z., Wang, G., Xu, S., Xiao, W., Gao, Y., et al. (2022) · Cancer Science · doi:10.1111/cas.15385 · Cited by 13

Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype

Amens, J. N., Bahçecioğlu, G., Dwyer, K. D., Yue, X. S., Stack, M. S., Hilliard, T. S., & Zorlutuna, P. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2023.122110 · Cited by 11

A nomogram based on collagen signature for predicting the immunoscore in colorectal cancer

Jiang, W., Yu, X., Dong, X., Long, C., Chen, D., Cheng, J., Yan, B., Xu, S., Lin, Z., Chen, G., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1269700 · Cited by 11

A computational diffusion model to study antibody transport within reconstructed tumor microenvironments

Cartaxo, A. L., de Almeida, J., Gualda, E. J., Marsal, M., Loza‐Álvarez, P., Brito, C., & Isidro, I. A. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-03854-2 · Cited by 11

Parallels between the extracellular matrix roles in developmental biology and cancer biology

Yuzhalin, A. E. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.09.010 · Cited by 11

Collagen score in the tumor microenvironment predicts the prognosis of rectal cancer patients after neoadjuvant chemoradiotherapy

Dong, X., Huang, Y., Yu, X., Huang, M., Jiang, W., Chen, D., Wang, G., Zhuo, S., Chi, P., & Yan, J. (2021) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2021.12.023 · Cited by 12

A Label-Free Segmentation Approach for Intravital Imaging of Mammary Tumor Microenvironment

Burkel, B. M., Inman, D. R., Virumbrales-Muñoz, M., Hoffmann, E. J., & Ponik, S. M. (2022) · Journal of Visualized Experiments · doi:10.3791/63413 · Cited by 10

Dynamics of actinotrichia, fibrous collagen structures in zebrafish fin tissues, unveiled by novel fluorescent probes

Kuroda, J., Hino, H., & Kondo, S. (2024) · PNAS Nexus · doi:10.1093/pnasnexus/pgae266 · Cited by 10

Collagen architecture in triple negative breast cancer

Dinkel, Z., Baker, A., Akins, A., King, K. L., Harrington, M., Kunkel, D., Gao, Z., Ye, T., & Dunn, H. W. (2025) · PLoS ONE · doi:10.1371/journal.pone.0324655 · Cited by 10

Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer

Parikainen, M., Suwal, U., Rappu, P., Heino, J., & Sahlgren, C. (2026) · Science Advances · doi:10.1126/sciadv.aea9562 · Cited by 11

Modeling multicellular dynamics regulated by extracellular-matrix-mediated mechanical communication via active particles with polarized effective attraction

Zheng, Y., Fan, Q., Eddy, C., Wang, X., Sun, B., Ye, F.-F., & Jiao, Y. (2020) · Physical review. E · doi:10.1103/physreve.102.052409 · Cited by 10

A comprehensive review of computational and image analysis techniques for quantitative evaluation of striated muscle tissue architecture

Morris, T. A., Eldeen, S., Tran, R. D. H., & Grosberg, A. (2022) · Biophysics Reviews · doi:10.1063/5.0057434 · Cited by 10

“Pleomorphic adenoma in salivary glands: Insights from a 100-patient analysis”

Sheereen, S., Manva, M. Z., Sheereen, S., Patil, N. N., Abdelrahim, R. K., & Afroz, M. M. (2024) · Journal of Oral and Maxillofacial Pathology · doi:10.4103/jomfp.jomfp_452_23 · Cited by 10

Application of microfluidic technology in cancer research and therapy

Azadi, S., Es, H. A., Kulasinghe, A., Bordhan, P., & Warkiani, M. E. (2020) · Advances in clinical chemistry · doi:10.1016/bs.acc.2020.02.012 · Cited by 10

Biological gel-based microchamber array for tumor cell proliferation and migration studies in well-controlled biochemical gradients

Yao, J., Li, G., Jiao, Y., Zheng, Y., Liu, Y., Wang, G., Zhou, L., Zhang, H., Zhang, X., Shuai, J., et al. (2021) · Lab on a Chip · doi:10.1039/d0lc00951b · Cited by 10

Re-engineering Artificial Neoplastic Milieus: Taking Lessons from Mechano- and Topobiology

Leal‐Egaña, A., Balland, M., & Boccaccini, A. R. (2019) · Trends in biotechnology · doi:10.1016/j.tibtech.2019.08.003 · Cited by 10

Understanding the interplay between extracellular matrix topology and tumor-immune interactions: Challenges and opportunities

Fan, Y., Chiu, A., Zhao, F., & George, J. T. (2024) · Oncotarget · doi:10.18632/oncotarget.28666 · Cited by 10

Micron-resolution fiber mapping in histology independent of sample preparation

Georgiadis, M., der Heiden, F. A., Abbasi, H., Ettema, L., Nirschl, J., Taghavi, H. M., Wakatsuki, M., Liu, A., Ho, W. H. D., Carlson, M. L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64896-9 · Cited by 9

Cell Mechanics Regulates the Dynamic Anisotropic Remodeling of Fibril Matrix at Large Scale

Ouyang, M., Hu, Y., Chen, W., Li, H., Ji, Y., Qiu, L., Zhu, L., Ji, B., Bu, B., & Deng, L. (2023) · Research · doi:10.34133/research.0270 · Cited by 9

A Non-Local Kinetic Model for Cell Migration: A Study of the Interplay Between Contact Guidance and Steric Hindrance

Conte, M. L., & Loy, N. (2023) · SIAM Journal on Applied Mathematics · doi:10.1137/22m1506389 · Cited by 9

Multimodal characterization of the collagen hydrogel structure and properties in response to physiologically relevant pH fluctuations

Shtrauchler, O., Nativ‐Roth, E., Sanchez, D. S., Zaiden, M., & Vidavsky, N. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.02.031 · Cited by 9

Nomograms integrating the collagen signature and systemic immune-inflammation index for predicting prognosis in rectal cancer patients

Yu, X., Jiang, W., Dong, X., Yan, B., Xu, S., Lin, Z., Zhuo, S., & Yan, J. (2024) · BJS Open · doi:10.1093/bjsopen/zrae014 · Cited by 10

Magnetic Field Alignment, a Perspective in the Engineering of Collagen-Silica Composite Biomaterials

Debons, N., Matsumoto, K., Hirota, N., Coradin, T., Ikoma, T., & Aimé, C. (2021) · Biomolecules · doi:10.3390/biom11050749 · Cited by 9

Estimating quantitative physiological and morphological tissue parameters of murine tumor models using hyperspectral imaging and optical profilometry

Tomanič, T., Rogelj, L., Stergar, J., Markelc, B., Božič, T., Kranjc, S., Serša, G., & Milanič, M. (2022) · Journal of Biophotonics · doi:10.1002/jbio.202200181 · Cited by 9

A Miniaturized Screening Platform to Identify Novel Regulators of Extracellular Matrix Alignment

Jones, C. E., Sharick, J. T., Sizemore, S. T., Cukierman, E., Strohecker, A. M., & Leight, J. L. (2022) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0157 · Cited by 9

Association of collagen deep learning classifier with prognosis and chemotherapy benefits in stage II‐III colon cancer

Jiang, W., Wang, H., Chen, W., Zhao, Y., Yan, B., Chen, D., Dong, X., Cheng, J., Lin, Z., Zhuo, S., et al. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10526 · Cited by 10

Development and validation of a collagen signature to predict the prognosis of patients with stage II/III colorectal cancer

Dong, S., Wang, H., Ji, H., Hu, Y., Zhao, S., Yan, B., Wang, G., Lin, Z., Zhu, W., Lü, J., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106746 · Cited by 9

Evaluation of immunohistopathological profile of tubular and solid canine mammary carcinomas

Borghesi, J., da Silva, M. G. K. C., Guimarães, K. D. O. P., Mario, L. C., da Anunciação, A. R. D. A., Rabêlo, A. C. S., Hayashi, R. G., Lima, M. F., Miglino, M. A., Favaron, P. O., et al. (2021) · Research in Veterinary Science · doi:10.1016/j.rvsc.2021.02.004 · Cited by 9

Extracellular matrix reorganization during endometrial decidualization

Gebril, M., Mulder, S., Das, R., & Nallasamy, S. (2025) · Histochemistry and Cell Biology · doi:10.1007/s00418-025-02411-3 · Cited by 8

Matrix-integrated microfluidic tumor models for evaluating drug delivery systems and pre-clinical testing

Guerrero‐López, P., Alamán‐Díez, P., Hernández-Hatibi, S., Balsas, P., & Garcia-Aznar, J. M. (2026) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2026.115836 · Cited by 8

Mathematical modelling of cell migration

Butler, G., Rudge, J., & Dash, P. R. (2019) · Essays in Biochemistry · doi:10.1042/ebc20190020 · Cited by 8

Bioconjugation of COL1 protein on liquid-like solid surfaces to study tumor invasion dynamics

Nguyen, D., Pedro, D. I., Pepe, A., Rosa, J. G., Bowman, J. I., Trachsel, L., Golde, G. R., Suzuki, I., Lavrador, J. M., Nguyen, N. T. Y., et al. (2023) · Biointerphases · doi:10.1116/6.0002083 · Cited by 8

High-Accuracy Cancer Cell Viability Evaluation Based on Multi-Physical Properties Extraction

Zhang, Y., Wei, M., Zhang, F., & Guo, J. (2022) · Heliyon · doi:10.1016/j.heliyon.2023.e14966 · Cited by 8

Diagnostic and prognostic significance of keloid-like collagen remodeling patterns in the extracellular matrix of colorectal cancer

Imanbayev, N. M., Iztleuov, Y. M., Kamyshanskiy, Y., & Zhumasheva, A. (2024) · Pathology & Oncology Research · doi:10.3389/pore.2024.1611789 · Cited by 8

Re-engineered cell-derived extracellular matrix as a new approach to clarify the role of native ECM

Yong, I., Oh, S. W., & Kim, P. (2020) · Methods in cell biology · doi:10.1016/bs.mcb.2019.12.007 · Cited by 8

EFA6B regulates a stop signal for collective invasion in breast cancer

Fayad, R., Rojas, M. V., Partisani, M., Finetti, P., Dib, S., Abélanet, S., Virolle, V., Farina, A. K., Cabaud, O., Lopez, M., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22522-4 · Cited by 8

Patient-Derived Xenografts as an Innovative Surrogate Tumor Model for the Investigation of Health Disparities in Triple Negative Breast Cancer

Matossian, M. D., Giardina, A. A., Wright, M. K., Elliott, S. G., Loch, M. M., Nguyen, K., Zea, A. H., Lau, F. H., Moroz, K., Riker, A. I., et al. (2020) · Women s Health Reports · doi:10.1089/whr.2020.0037 · Cited by 9

Morphological quantification of proliferation-to-invasion transition in tumor spheroids

He, Y., Xiong, L., Gao, X., Hai, M., Liu, Y., Wang, G., Chen, G., Shuai, J., Jiao, Y., Zhang, X., et al. (2019) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2019.129460 · Cited by 8

Correlation between procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 and breast cancer.

Hu, H., Wang, C.-F., Wei, X., Lv, J.-X., Cao, X., Shi, Y., Han, L., & Zhang, Y.-N. (2019) · Europe PMC (PubMed Central) · Cited by 8

Three-dimensional pore network characterization of reconstructed extracellular matrix

Park, S., Lim, S., Siriviriyakul, P., & Jeon, J. S. (2020) · Physical review. E · doi:10.1103/physreve.101.052414 · Cited by 8

Collagen synthesis and gap junctions: the highway for metastasis of ovarian cancer

Lyu, Y., & Feng, C. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00546-0 · Cited by 8

Deposition of collagen III and alterations in basement membrane integrity as candidate prognostic markers in prostate cancer

Pinheiro, L. C. L., Pupim, A. C. E., Pereira, É. R., Ahrens, T. M., Mendonça, A. C., Francelino, A. L., Araújo, E. J. D. A., Guembarovski, A. F. M. L., Fuganti, P. E., Vanzela, A. L. L., et al. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114077 · Cited by 7

The underlying difference of metastatic and non-metastatic breast cancer cells in configuring type I collagen fibres to promote migration by cell mechanics

Ouyang, M., Chen, W., Zhou, T., Luo, T., Liu, L., Bu, B., Deng, L., Bu, B., & Deng, L. (2025) · Mechanobiology in Medicine · doi:10.1016/j.mbm.2025.100113 · Cited by 7

Mimicking Gastric Cancer Collagen Reorganization with Decellularized ECM-Based Scaffolds

Corro, N. B., Alarcón, S., Astroza, Á., González‐Stegmaier, R., & Añazco, C. C. (2025) · Biology · doi:10.3390/biology14081067 · Cited by 7

Active-gel theory for multicellular migration of polar cells in the extra-cellular matrix

Adar, R. M., & Joanny, J. (2022) · New Journal of Physics · doi:10.1088/1367-2630/ac78fc · Cited by 7

ER stress signaling at the interphase between MASH and HCC

Hazari, Y., Chevet, É., Bailly‐Maitre, B., & Hetz, C. A. (2024) · Hepatology · doi:10.1097/hep.0000000000000893 · Cited by 8

Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids

Ang, I., Yousafzai, M. S., Yadav, V., Mohler, K., Rinehart, J., Bouklas, N., & Murrell, M. P. (2024) · APL Bioengineering · doi:10.1063/5.0191765 · Cited by 7

Mechanical cues guide the formation and patterning of 3D spheroids in fibrous environments

Sharma, S., Agashe, A., Hill, J. C., Ganguly, K., Sharma, P., Richards, T. D., Huang, W., Kaczorowski, D. J., Sánchez, P. G., Kapania, R. K., et al. (2025) · PNAS Nexus · doi:10.1093/pnasnexus/pgaf263 · Cited by 7

Controlled generation of cell–laden hydrogel microspheres with core–shell scaffold mimicking microenvironment of tumor

Li, Y., Hai, M., Zhao, Y., Lv, Y., He, Y., Chen, G., Liu, L., Liu, R., & Zhang, G. (2018) · Chinese Physics B · doi:10.1088/1674-1056/27/12/128703 · Cited by 7

Deletion of Calcineurin Promotes a Protumorigenic Fibroblast Phenotype

Lieberman, A. E., Barrett, R., Kim, J., Zhang, K. L., Avery, D., Monslow, J., Kim, H., Kim, B., Puré, E., & Ryeom, S. W. (2019) · Cancer Research · doi:10.1158/0008-5472.can-19-0056 · Cited by 7

Prognostic value of tumor stromal collagen features in patients with hepatocellular carcinoma revealed by second-harmonic generation microscopy

Lin, L., Chen, G., Chen, Z., Lu, J., Zhu, W., Zhong, J., Peng, F., & Huang, A. (2020) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2020.104513 · Cited by 7

The Case for Cancer-Associated Fibroblasts: Essential Elements in Cancer Drug Discovery?

Brewer, G., Fortier, A.-M., Park, M., & Moraes, C. (2022) · Future Drug Discovery · doi:10.4155/fdd-2021-0004 · Cited by 8

Unusual Suspects: Bone and Cartilage ECM Proteins as Carcinoma Facilitators

Sorvina, A., Antoniou, M., Esmaeili, Z., & Kochetkova, M. (2023) · Cancers · doi:10.3390/cancers15030791 · Cited by 7

Extracellular Hsp90 Binds to and Aligns Collagen-1 to Enhance Breast Cancer Cell Invasiveness

Singh, P., Ramanathan, V., Zhang, Y., Georgakoudi, I., & Jay, D. G. (2023) · Cancers · doi:10.3390/cancers15215237 · Cited by 7

Mechanical communication-associated cell directional migration and branching connections mediated by calcium channels, integrin β1, and N-cadherin

Ouyang, M., Zhu, Y., Wang, J., Zhang, Q., Hu, Y., Bu, B., Guo, J., & Deng, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.942058 · Cited by 7

An entropy-based approach for assessing the directional persistence of cell migration

Liu, Y., Jiao, Y., Li, X., Li, G., Wang, W., Liu, Z., Qin, D., Zhong, L., Liu, L., Shuai, J., et al. (2024) · Biophysical Journal · doi:10.1016/j.bpj.2024.02.010 · Cited by 6

Topical Nanoliposomal Collagen Delivery for Targeted Fibril Formation by Electrical Stimulation

Brilian, A. I., Lee, S. H., Setiawati, A., Kim, C. H., Ryu, S. R., Chong, H., Jo, Y., Jeong, H., Ju, B., Kwon, O., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400693 · Cited by 6

Tensile force field plays a crucial role in local invasion of tumor cells through a mechano-chemical coupling mechanism

Meng, J., Xu, X., Jiang, C., Xia, P., Xu, P., Tian, L., Xu, Y., Li, D., Tan, Y., & Ji, B. (2024) · Soft Matter · doi:10.1039/d4sm00335g · Cited by 6

Effect of cell-nanostructured substrate interactions on the capture efficiency of HeLa cells

Kong, J., Liu, Y., Du, X., Wang, K., Chen, W., Huang, D., Wei, Y., & Mao, H. (2020) · Biomedical Materials · doi:10.1088/1748-605x/abcf5c · Cited by 6

Tissue engineered scaffolds as 3D models for prostate cancer metastasis to bone

Safarulla, S., Khillar, P. S., Kini, S., & Jaiswal, A. K. (2021) · Materials Today Communications · doi:10.1016/j.mtcomm.2021.102641 · Cited by 6

Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy

Peres, C., Nardin, C., Yang, G., & Mammano, F. (2022) · Biomedical Optics Express · doi:10.1364/boe.444525 · Cited by 6

Identification of the collagen family as prognostic biomarkers in papillary thyroid carcinoma

Niu, J., Guo, W., Chen, Y., & Jiang, N. (2022) · Endocrine · doi:10.1007/s12020-022-03175-9 · Cited by 6

Target finding in fibrous biological environments

Gomez, D., Teomy, E., Lesman, A., & Shokef, Y. (2020) · New Journal of Physics · doi:10.1088/1367-2630/abb64b · Cited by 6

Association of the imaging characteristics of desmoplasia on digital breast tomosynthesis and the Ki-67 proliferation index in invasive breast cancer

Samaržija, K., & Jurjević, Z. (2021) · Croatian Medical Journal · doi:10.3325/cmj.2021.62.59 · Cited by 6

Histolytics: A panoptic spatial analysis framework for interpretable histopathology

Lehtonen, O., Nordlund, N. K., Salloum, S., Kalliala, I. E. J., Virtanen, A., & Hautaniemi, S. (2025) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2025.11.022 · Cited by 5

The modeling study of the effect of morphological behaviors of extracellular matrix fibers on the dynamic interaction between tumor cells and antitumor immune response

Jia, G., Yang, H. C., Wang, K., Huang, D., Chen, W., & Shan, Y. (2022) · International Journal for Numerical Methods in Biomedical Engineering · doi:10.1002/cnm.3633 · Cited by 5

Nonlinear microscopy and deep learning classification for mammary gland microenvironment studies

Aghigh, A., Preston, S. E. J., Jargot, G., Ibrahim, H., Rincon, S. V. D., & Légaré, F. (2023) · Biomedical Optics Express · doi:10.1364/boe.487087 · Cited by 5

A kinetic derivation of spatial distributed models for tumor-immune system interactions

Conte, M., & Travaglini, R. (2025) · Chaos Solitons & Fractals · doi:10.1016/j.chaos.2025.116969 · Cited by 5

Micro-tensile rheology of fibrous gels quantifies strain-dependent anisotropy

Goren, S., Ergaz, B., Barak, D., Sorkin, R., & Lesman, A. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.03.028 · Cited by 5

EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening

Cappelletto, A., Alfì, E., Volf, N., Vu, T. V. A., Bortolotti, F., Ciucci, G., Vodret, S., Fantuz, M., Perin, M., Colliva, A., et al. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02942-4 · Cited by 5

Computational modeling for prediction of the shear stress of three-dimensional isotropic and aligned fiber networks

Park, S. (2017) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2017.06.019 · Cited by 5

Ultrastructural Changes of the Peri-Tumoral Collagen Fibers and Fibrils Array in Different Stages of Mammary Cancer Progression

Franchi, M., Masola, V., Onisto, M., Franchi, L., Mangani, S., Zolota, V., Piperigkou, Z., & Karamanos, N. K. (2025) · Cells · doi:10.3390/cells14131037 · Cited by 5

Microphysiological systems for metastasis research: a stepwise approach

Sharko, V., Ochoa, I., & Solanas, E. (2025) · Cellular Oncology · doi:10.1007/s13402-025-01110-4 · Cited by 4

Compression‐Tension‐Asymmetry and Stiffness Nonlinearity of Collagen‐Matrigel Composite Hydrogels

Böhringer, D., Hinrichsen, J., Gataulin, R., Wiedenmann, S., Spörrer, M., Sherifova, S., Steinmann, P., Holzapfel, G. A., Fabry, B., & Budday, S. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202503052 · Cited by 5

Mechanical factors driving cancer progression

Lichtenberg, J. Y., Tran, S. K., & Hwang, P. Y. (2023) · Advances in cancer research · doi:10.1016/bs.acr.2023.06.002 · Cited by 5

Multiphoton excited polymerized biomimetic models of collagen fiber morphology to study single cell and collective migration dynamics in pancreatic cancer

Mancha, S., Horan, M., Pasachhe, O., Keikhosravi, A., Eliceiri, K. W., Matkowskyj, K. A., Notbohm, J., Skala, M. C., & Campagnola, P. J. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.08.026 · Cited by 4

Biotechnological advances in 3D modeling of cancer initiation. Examples from pancreatic cancer research and beyond

Handschin, C., Shalhoub, H., Mazet, A., Guyon, C., Dusserre, N., Boutet-Robinet, E. A., Oliveira, H., & Guillermet‐Guibert, J. (2025) · Biofabrication · doi:10.1088/1758-5090/adb51c · Cited by 5

Deep learning reveals how cells pull, buckle, and navigate fibrous environments

Padhi, A., Daw, A., Agashe, A., Sawhney, M., Talukder, M. M., Pour, M. M. H., Jafari, M., Genin, G. M., Alisafaei, F., Kale, S., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2424047122 · Cited by 4

Laser-speckle-contrast projection tomography for three-dimensional shear wave imaging

Chao, P., & Li, P. (2019) · Optics Letters · doi:10.1364/ol.44.004809 · Cited by 4

Mechanobiology of cancerogenesis

Raudenská, M., Navrátil, J., Gumulec, J., & Masařík, M. (2021) · Klinicka onkologie · doi:10.48095/ccko2021202 · Cited by 4

Effect of extracellular matrix fiber cross-linkage on cancer cell motility and surrounding matrix deformation

Omata, S., Fukuda, K., Sakai, Y., Ohuchida, K., & MORITA, Y. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.06.019 · Cited by 4

Nonlinear dynamics of cell migration in anisotropic microenvironment*

Liu, Y., He, D., Jiao, Y., Li, G., Zheng, Y., Fan, Q., Wang, G., Yao, J., Chen, G., Lou, S., et al. (2021) · Chinese Physics B · doi:10.1088/1674-1056/ac11d5 · Cited by 4

Polychromatic Polarization Microscopy Differentiates Collagen Fiber Signatures in Benign Pancreatic Tissue and Pancreatic Ductal Adenocarcinoma

Chitsaz, M., Yang, L., Rayes-Danan, R., Savari, O., Li, B., Shribak, M. I., Eliceiri, K. W., & Loeffler, A. G. (2025) · Modern Pathology · doi:10.1016/j.modpat.2025.100768 · Cited by 3

Stiffness matters: Exploiting mechanotransduction to guide cellular behavior and potentiate cancer therapy

Wang, J., Long, L., Sun, C., Li, P., Yao, S., Wang, N., & Xiao, J. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.166215 · Cited by 3

Integrative Multi‐Omics Analysis Uncovers Immunological Phenotypes Predictive of Combinatorial Immunotherapy Response in Gastric Cancer

Wang, J., Zhang, W., Zhang, J., Zhao, C., Zhang, W., Fang, M., Chen, F., Wu, Z., Xu, X., Yu, Z., et al. (2025) · Advanced Science · doi:10.1002/advs.202514482 · Cited by 6

Collagen nanofiber alignment attenuates leader-follower energetic and metabolic differences during collective migration in pancreatic cancer

Pickett, M., Kamra, M., Castilla‐Casadiego, D. A., Noori, S., Matsui, W. H., Rosales, A. M., Zoldan, J., & Parekh, S. H. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.11.031 · Cited by 3

Fibre orientations in collagen-containing tissues revealed with computational scattered light imaging and polarimetric second harmonic generation microscopy

Ettema, L., Mažeika, V., Alizadeh, M., Abbasi, H., Barzda, V., & Menzel, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-30627-9 · Cited by 3

Dasatinib demonstrates efficacy in organoid derived paclitaxel-resistant Trp53/Cdh1-deficient mouse gastric adenocarcinoma with peritoneal metastasis

Liu, W., Li, L., Guo, L., Li, H., Tang, Z., Wang, X. J., Huang, L., & Sun, Y. (2025) · Cell Regeneration · doi:10.1186/s13619-025-00232-2 · Cited by 3

Characterization of vascular density and collagenous matrix in oral pleomorphic adenomas

Rocha, F. G. C. W., Reis, S. R. D. A., de ARAÚJO, R. P., Martins, G. B., & Medrado, A. R. A. P. (2020) · Minerva Dental and Oral Science · doi:10.23736/s0026-4970.19.04308-5 · Cited by 3

Emulation and evaluation of tumor cell combined chemotherapy in isotropic/anisotropic collagen fiber microenvironments

Zhou, L., Li, G., Yao, J., Wang, J., Yao, X., Ye, Z., Zheng, D., Song, K., Zhang, H., Zhang, X., et al. (2024) · Lab on a Chip · doi:10.1039/d4lc00051j · Cited by 3

Partial cystectomy as a surgical option for colorectal cancer patients with pathological bladder invasion: an original retrospective study

Lan, B., Luo, R., Li, Y., Wang, S., Jiang, W., Zhong, Y., Zhang, X., Zheng, Q., He, Z., Ma, B., et al. (2025) · Therapeutic Advances in Gastroenterology · doi:10.1177/17562848241308387 · Cited by 3

Multimodal tumor microenvironment signature of colorectal cancer for prediction prognosis and chemotherapy benefit

Jiang, W., Yang, K., Xiao, C., Ji, H., Yan, B., Zhao, S., Zhang, B., Cheng, J., Xu, S., Wang, G., et al. (2025) · npj Precision Oncology · doi:10.1038/s41698-025-01069-3 · Cited by 6

Protocols for Studies on Stromal Cells in Prostate Cancer

Leach, D. A., & Buchanan, G. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7845-8_12 · Cited by 3

Biofabrication of advanced in vitro and ex vivo cancer models for disease modeling and drug screening

Nairon, K. G., & Skardal, A. (2021) · Future Drug Discovery · doi:10.4155/fdd-2020-0034 · Cited by 3

Cecal microbiota and mammary gland microRNA signatures are related and modifiable by dietary flaxseed with implications for breast cancer risk

Wu, D., Thompson, L. U., & Comelli, E. M. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.02290-23 · Cited by 3

Bioprinting Cell-Laden Hydrogels for Studies of Epithelial Tissue Morphogenesis

Nerger, B. A., & Nelson, C. M. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3854-5_7 · Cited by 3

Collective ECM remodeling organizes 3D collective cancer invasionPreprint

Kim, J., Zheng, Y., Alobaidi, A. A., Nan, H., Tian, J., Jiao, Y., & Sun, B. (2019) · arXiv (Cornell University) · doi:10.48550/arxiv.1903.03290 · Cited by 3

Collagen modification remodels the sarcoma tumor microenvironment and promotes resistance to immune checkpoint inhibitionPreprint

Pan, H., Liu, Y., Fuller, A. M., Williams, E. F., Fraietta, J. A., & Eisinger‐Mathason, T. S. K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.28.601055 · Cited by 4

Mechano-mediated M2 macrophage polarization and immune suppression in stiffened tumor microenvironmentPreprint

Sapudom, J., Tipay, P. S., & Teo, J. C. M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.29.605566 · Cited by 3

Thermostability of rat sarcoma M1 procollagen solutions, procollagen fibers and whole tissues

Monaselidze, J., Kikalishvili, L., Ramishvili, M., Gorgoshidze, M., & Kiladze, M. (2020) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-020-09332-4 · Cited by 2

Directed invasion of cancer cell spheroids inside 3D collagen matrices oriented by microfluidic flow in experiment and simulation

Geiger, F., Schnitzler, L. G., Brugger, M. S., Westerhausen, C., & Engelke, H. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264571 · Cited by 13

Regulation of migration of chemotactic tumor cells by the spatial distribution of collagen fiber orientation

Azimzade, Y., Saberi, A. A., & Sahimi, M. (2019) · Physical review. E · doi:10.1103/physreve.99.062414 · Cited by 23

Engineering a 3D collective cancer invasion model with control over collagen fiber alignment

Su, C., Burchett, A. A., Dunworth, M., Choi, J. S., Ewald, A. J., Ahn, E. H., & Kim, D. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120922 · Cited by 37

Global collective invasion occurs with minimal effort on aligned collagen fibers via long distance force transmission through soft matrices

Bagchi, A., & Pathak, A. (2022) · Biophysical Journal · doi:10.1016/j.bpj.2021.11.1417

Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread

Kim, D., Ewald, A. J., Park, J., Gupta, K., Kwak, M. K., Gray, R. S., Su, C., Seo, J., An, S. S., & Levchenko, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-32010-3 · Cited by 25