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Cited by 812

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

Open access
Qiu, Meng, Wang, Dou, Liang, Weiyuan, Liu, Liping, Zhang, Yin, Chen, Xing, Sang, David Kipkemoi, Xing, Chenyang, Li, Zhongjun, Dong, Biqin, Xing, Feng, Fan, Dianyuan, Bao, Shiyun, Zhang, Han, Cao, Yihai·2018·Proceedings of the National Academy of Sciences

Abstract

Significance: Precision delivery of cancer drugs to tumor site is crucial for improving therapeutic efficacy and minimizing adverse effects. Despite tremendous efforts, current drug delivery systems remain an unmet clinical need for cancer therapy. Herein, we propose a unique concept of applying external light to control drug delivery in cancer tissues. In preclinical cancer models, we demonstrate that the near-infrared light-induced decomposition of black phosphorus hydrogel accurately releases drugs in tumor tissues to eradicate subcutaneous breast and melanoma cancers without causing any adverse effects. We believe that our therapeutic system can be used for effective treatment of most cancer types. Our findings may likely bring about a paradigm shift in clinical treatment of cancer and millions of cancer patients will benefit from our findings.

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Crossref · 10.1073/pnas.1714421115

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Metadata

Authors
Qiu, M., Wang, D., Liang, W., Liu, L., Zhang, Y., Chen, X., Sang, D. K., Xing, C., Li, Z., Dong, B., Xing, F., Fan, D., Bao, S., Zhang, H., & Cao, Y.
Venue
Proceedings of the National Academy of Sciences
Published
2018-01-02
Volume
115
Issue
3
Pages
501-506
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2782504069
Cited by
812
References
4
FWCI
45.59
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy. https://app.cochat.ai/papers/10.1073/pnas.1714421115
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Qiu, M., Wang, D., Liang, W., Liu, L., Zhang, Y., Chen, X., Sang, D. K., Xing, C., Li, Z., Dong, B., Xing, F., Fan, D., Bao, S., Zhang, H., & Cao, Y. (2018). Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1714421115

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.