The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes
Open accessAbstract
Significance: The clinical management of nonhealing ulcers requires advanced materials that improve wound-closure rates without relying on the release of drugs or other growth factors that could potentially lead to concerns regarding systemic deleterious side effects. We report the synthesis, characterization, and performance of a biodegradable antioxidant shape-conforming regenerative dressing that exploits α3β1 and α6β1 integrin-binding interactions to promote dermal tissue regeneration. A laminin-derived peptide grafted onto a thermoresponsive citrate-based macromolecular scaffold facilitates the adhesion and spreading of skin cells throughout the hydrogel and also significantly increases cell proliferation and migration in an integrin-dependent manner. We use a splinted excisional wound diabetic mouse model to demonstrate that application of this thermoresponsive regenerative dressing significantly accelerates wound closure in vivo.
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Cites
GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
Eden, E., Navon, R., Steinfeld, I., Lipson, D., & Yakhini, Z. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-48 · Cited by 3,356
Smiell, J. M., Wieman, T. J., Steed, D. L., Perry, B. H., Sampson, A. R., & Schwab, B. H. (1999) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.1999.00335.x · Cited by 454
Laminins: Roles and Utility in Wound Repair
Iorio, V., Troughton, L. D., & Hamill, K. J. (2015) · Advances in Wound Care · doi:10.1089/wound.2014.0533 · Cited by 169
Cited by
Zhao, X., Liang, Y., Huang, Y., He, J., Han, Y., & Guo, B. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910748 · Cited by 814
Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing
Kharaziha, M., Baidya, A., & Annabi, N. (2021) · Advanced Materials · doi:10.1002/adma.202100176 · Cited by 721
Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing
Yang, Z., Huang, R., Zheng, B., Guo, W., Li, C., He, W., Wei, Y., Du, Y., Wang, H., Wu, D., et al. (2021) · Advanced Science · doi:10.1002/advs.202003627 · Cited by 609
Recent advances in wet adhesives: Adhesion mechanism, design principle and applications
Cui, C., & Liu, W. (2021) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2021.101388 · Cited by 557
Shiekh, P. A., Singh, A., & Kumar, A. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120020 · Cited by 443
Metadata
- Authors
- Zhu, Y., Cankova, Z., Iwanaszko, M., Lichtor, S., Mrksich, M., & Ameer, G. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2018-06-11
- Volume
- 115
- Issue
- 26
- Pages
- 6816-6821
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2808115170
- Cited by
- 165
- References
- 3
- FWCI
- 10.63
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhu, Y., Cankova, Z., Iwanaszko, M., Lichtor, S., Mrksich, M., & Ameer, G. A. (2018). Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1804262115
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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