The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study
Open accessAbstract
Significance: Prostate cancer is the most common nonskin cancer in the United States, where approximately 1 in 9 men will be diagnosed in their lifetime. The prostate is near several vital structures, such as the urethra and neurovascular bundle, and whole gland treatments for prostate cancer can disrupt normal urinary, bowel, and sexual functioning. Here we report the initial results of a clinical trial for nanoparticle-based photothermal cancer therapy. The trial was designed to perform ultrafocal photothermal ablation of cancerous tumors within the prostate. Gold-silica nanoparticles designed to absorb near-infrared light at wavelengths of high tissue transparency provide a highly localized light-based strategy for the treatment of prostate cancer, with substantially reduced risks for deleterious treatment-related side effects.
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Siegel, R. L., Miller, K. D., & Jemal, A. (2019) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21551 · Cited by 20,160
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Mie, G. (1908) · Annalen der Physik · doi:10.1002/andp.19083300302 · Cited by 11,537
A clearer vision for in vivo imaging
Weissleder, R. (2001) · Nature Biotechnology · doi:10.1038/86684 · Cited by 3,839
Diverse Applications of Nanomedicine
Pelaz, B., Alexiou, C., Alvarez-Puebla, R. A., Alves, F., Andrews, A. M., Ashraf, S., Balogh, L. P., Ballerini, L., Bestetti, A., Brendel, C., et al. (2017) · ACS Nano · doi:10.1021/acsnano.6b06040 · Cited by 1,350
Self-citationRecent Progress in Cancer Thermal Therapy Using Gold Nanoparticles
Abadeer, N. S., & Murphy, C. J. (2016) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.5b11232 · Cited by 919
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Exploring treatment options in cancer: tumor treatment strategies
Liu, B., Zhou, H., Tan, L., Siu, K. T. H., & Guan, X.-Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01856-7 · Cited by 1,201
Phototherapy in cancer treatment: strategies and challenges
Cai, Y., Chai, T., Nguyen, W., Liu, J., Xiao, E., Ran, X., Ran, Y., Du, D., Chen, W., & Chen, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02140-y · Cited by 453
Li, S., Deng, Q., Zhang, Y., Li, X., Wen, G., Cui, X., Wan, Y., Huang, Y., Chen, J., Liu, Z., et al. (2020) · Advanced Materials · doi:10.1002/adma.202001146 · Cited by 369
Metadata
- Authors
- Rastinehad, A. R., Anastos, H., Wajswol, E., Winoker, J. S., Sfakianos, J. P., Doppalapudi, S. K., Carrick, M. R., Knauer, C. J., Taouli, B., Lewis, S. C., Tewari, A. K., Schwartz, J. A., Canfield, S. E., George, A. K., West, J. L., & Halas, N. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2019-08-26
- Volume
- 116
- Issue
- 37
- Pages
- 18590-18596
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2971326475
- Cited by
- 884
- References
- 5
- FWCI
- 37.98
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Rastinehad, A. R., Anastos, H., Wajswol, E., Winoker, J. S., Sfakianos, J. P., Doppalapudi, S. K., Carrick, M. R., Knauer, C. J., Taouli, B., Lewis, S. C., Tewari, A. K., Schwartz, J. A., Canfield, S. E., George, A. K., West, J. L., & Halas, N. J. (2019). Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1906929116
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
