Disrupted synaptic development in the hypoxic newborn brain

Cluster analysis and display of genome-wide expression patterns

Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 12,617 · see citing works

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,949 · see citing works

Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions

Salceda, S., & Caro, J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.36.22642 · Cited by 1,674 · see citing works

Very Low Birth Weight Outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 Through December 1996

Lemons, J. A., Bauer, C. R., Oh, W., Korones, S. B., Papile, L. A., Stoll, B. J., Verter, J. I., Temprosa, M. G., Wright, L. L., Ehrenkranz, R. A., et al. (2001) · PEDIATRICS · doi:10.1542/peds.107.1.e1 · Cited by 1,441 · see citing works

Gene-expression profiles in hereditary breast cancer.

Hedenfalk, I., Duggan, D., Chen, Y.-D., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Raffeld, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102223440801 · Cited by 978 · see citing works

Late Oligodendrocyte Progenitors Coincide with the Developmental Window of Vulnerability for Human Perinatal White Matter Injury

Back, S. A., Luo, N. L., Borenstein, N. S., Levine, J. M., Volpe, J. J., & Kinney, H. C. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-04-01302.2001 · Cited by 936 · see citing works

Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion

Back, S. A., Gan, X., Li, Y., Rosenberg, P. A., & Volpe, J. J. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-16-06241.1998 · Cited by 586 · see citing works

Synchronous Activity of Inhibitory Networks in Neocortex Requires Electrical Synapses Containing Connexin36

Deans, M. R., Gibson, J. R., Sellitto, C., Connors, B. W., & Paul, D. L. (2001) · Neuron · doi:10.1016/s0896-6273(01)00373-7 · Cited by 580 · see citing works

<i>Disabled-1</i> acts downstream of <i>Reelin</i> in a signaling pathway that controls laminar organization in the mammalian brain

Rice, D. S., Sheldon, M., D’Arcangelo, G., Nakajima, K., Goldowitz, D., & Curran, T. (1998) · Development · doi:10.1242/dev.125.18.3719 · Cited by 378 · see citing works

Microstructural Brain Development After Perinatal Cerebral White Matter Injury Assessed by Diffusion Tensor Magnetic Resonance Imaging

Hüppi, P. S., Murphy, B. P., Maier, S. E., Zientara, G. P., Inder, T. E., Barnes, P. D., Kikinis, R., Jolesz, F. A., & Volpe, J. J. (2001) · PEDIATRICS · doi:10.1542/peds.107.3.455 · Cited by 362 · see citing works

Spectrin tethers and mesh in the biosynthetic pathway

Matteis, M. A. D., & Morrow, J. S. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.13.2331 · Cited by 336 · see citing works

Mechanisms of perinatal brain injury

Inder, T. E., & Volpe, J. J. (2000) · Seminars in Neonatology · doi:10.1053/siny.1999.0112 · Cited by 288 · see citing works

Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development

Howell, B. W., Herrick, T. M., Hildebrand, J. D., Zhang, Y., & Cooper, J. A. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00608-4 · Cited by 258 · see citing works

Neuronal VEGF expression correlates with angiogenesis in postnatal developing rat brain.

Ogunshola, O., Stewart, W., Mihalcik, V., Solli, T., Madri, J., & Ment, L. (2000) · Brain research. Developmental brain research · doi:10.1016/s0165-3806(99)00125-x · Cited by 257 · see citing works

Development of layer I and the subplate in the rat neocortex

Bayer, S. A., & Altman, J. (1990) · Experimental Neurology · doi:10.1016/0014-4886(90)90062-w · Cited by 237 · see citing works

Undernutrition and the Developing Brain

Dobbing, J. (1970) · American journal of diseases of children · doi:10.1001/archpedi.1970.02100100075005 · Cited by 235 · see citing works

Morphogenesis of the Node of Ranvier: Co-Clusters of Ankyrin and Ankyrin-Binding Integral Proteins Define Early Developmental Intermediates

Lambert, S. B., Davis, J. Q., & Bennett, V. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07025.1997 · Cited by 216 · see citing works

Organization and postnatal development of callosal connections in the visual cortex of the rat

Olavarría, J. F., & Sluyters, R. C. V. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902390102 · Cited by 213 · see citing works

Reelin Regulates the Development and Synaptogenesis of the Layer-Specific Entorhino-Hippocampal Connections

Borrell, V., del Rı́o, J. A., Alcántara, S., Derer, M., Martı́nez, A., D’Arcangelo, G., Nakajima, K., Mikoshiba, K., Derer, P., Curran, T., et al. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-04-01345.1999 · Cited by 195 · see citing works

Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex

Chheda, M. G., Ashery, U., Thakur, P., Rettig, J., & Sheng, Z. (2001) · Nature Cell Biology · doi:10.1038/35070000 · Cited by 180 · see citing works

Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex

Rodríguez, M. Á., Pesold, C., Liu, W. S., Kriho, V., Guidotti, A., Pappas, G. D., & Costa, E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.050589797 · Cited by 178 · see citing works

School-Age Consequences of Birth Weight Less Than 750 g: A Review and Update

Taylor, H. G., Klein, N., & Hack, M. (2000) · Developmental Neuropsychology · doi:10.1207/s15326942dn1703_2 · Cited by 173 · see citing works

Ankyrins and cellular targeting of diverse membrane proteins to physiological sites

Bennett, V., & Chen, L. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00175-7 · Cited by 172 · see citing works

Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression

Pesold, C., Liu, W. S., Guidotti, A., Costa, E., & Caruncho, H. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3217 · Cited by 160 · see citing works

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration

Stephenson, D. T., Rash, K. S., Smalstig, B., Roberts, E. F., Johnstone, E., Sharp, J., Panetta, J., Little, S. P., Kramer, R. M., & Clemens, J. A. (1999) · Glia · doi:10.1002/(sici)1098-1136(199908)27:2 · Cited by 152 · see citing works

Conditional Disruption of the Aryl Hydrocarbon Receptor Nuclear Translocator (Arnt) Gene Leads to Loss of Target Gene Induction by the Aryl Hydrocarbon Receptor and Hypoxia-Inducible Factor 1α

Tomita, S., Sinal, C. J., Yim, S. H., & Gonzalez, F. J. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.10.0533 · Cited by 121 · see citing works

Functional Limitations and Special Health Care Needs of 10- to 14-Year-Old Children Weighing Less Than 750 Grams at Birth

Hack, M., Taylor, H. G., Klein, N., & Minich, N. M. (2000) · PEDIATRICS · doi:10.1542/peds.106.3.554 · Cited by 120 · see citing works

Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex

Rodríguez, M. Á., Pesold, C., Liu, W. S., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3550 · Cited by 119 · see citing works

Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain.

Ment, L., Schwartz, M. L., Makuch, R., & Stewart, W. B. (1998) · Brain research. Developmental brain research · doi:10.1016/s0165-3806(98)00139-4 · Cited by 116 · see citing works

Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus

Gómez‐Pinilla, F., So, V., & Kesslak, J. P. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02394-0 · Cited by 113 · see citing works

HIF-1α and p53 Promote Hypoxia-Induced Delayed Neuronal Death in Models of CNS Ischemia

Halterman, M. W., & Federoff, H. J. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7160 · Cited by 113 · see citing works

Maturation of Neuronal Form and Function in a Mouse Thalamo-Cortical Circuit

Warren, R. A., & Jones, E. G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00277.1997 · Cited by 105 · see citing works

Abnormal Cardiac Na + Channel Properties and QT Heart Rate Adaptation in Neonatal Ankyrin B Knockout Mice

Chauhan, V. S., Tuvia, S., Buhusi, M. C., Bennett, V., & Grant, A. O. (2000) · Circulation Research · doi:10.1161/01.res.86.4.441 · Cited by 102 · see citing works

Redistribution of synaptic vesicle antigens is correlated with the disappearance of a transient synaptic zone in the developing cerebral cortex

Chun, J. J. M., & Shatz, C. J. (1988) · Neuron · doi:10.1016/0896-6273(88)90078-5 · Cited by 98 · see citing works

Axon development in mouse cerebellum: Embryonic axon forms and expression of synapsin I

Mason, C. A. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90146-6 · Cited by 89 · see citing works

Diagnostic accuracy of neonatal brain imaging: A postmortem correlation of computed tomography and ultrasound scans

Pape, K. E., Bennett-Britton, S., Szymonowicz, W., Martin, D. J., Fitz, C. R., & Becker, L. E. (1983) · The Journal of Pediatrics · doi:10.1016/s0022-3476(83)80543-5 · Cited by 68 · see citing works

The fates of cells generated at the end of neurogenesis in developing mouse cortex

Levers, T. E., Edgar, J. M., & Price, D. J. (2001) · Journal of Neurobiology · doi:10.1002/neu.1056 · Cited by 66 · see citing works

MAG and MOG enhance neurite outgrowth of embryonic mouse spinal cord neurons

Turnley, A. M., & Bartlett, P. F. (1998) · Neuroreport · doi:10.1097/00001756-199806220-00013 · Cited by 65 · see citing works

Age-related changes in the distribution of visual callosal neurons following monocular enucleation in the rat

Rothblat, L. A., & Hayes, L. L. (1982) · Brain Research · doi:10.1016/0006-8993(82)90153-6 · Cited by 53 · see citing works

Interaction of the C-terminal domain of δ glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells

Hirai, H., & Matsuda, S. (1999) · Neuroscience Research · doi:10.1016/s0168-0102(99)00061-9 · Cited by 40 · see citing works

The Community Effect and Purkinje Cell Migration in the Cerebellar Cortex: Analysis of Scrambler Chimeric Mice

Yang, H., Jensen, P., & Goldowitz, D. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-02-00464.2002 · Cited by 37 · see citing works

Hypoxic-Ischemic Injury Acutely Disrupts Microtubule-Associated Protein 2 Immunostaining in Neonatal Rat Brain

Malinak, C., & Silverstein, F. S. (2009) · Biology of the Neonate · doi:10.1159/000244319 · Cited by 33 · see citing works

Unique Responses of Differentiating Neuronal Growth Cones to Inhibitory Cues Presented by Oligodendrocytes

Shibata, A., Wright, M., David, S., McKerracher, L. J., Braun, P. E., & Kater, S. B. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.1.191 · Cited by 27 · see citing works

Intracellular injection of synapsin I induces neurotransmitter release in C1 neurons of Helix pomatia contacting a wrong target

Fiumara, F., Onofri, F., Benfenati, F., Montarolo, P. G., & Ghirardi, M. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00063-x · Cited by 24 · see citing works

Perinatal expression of heat shock proteins HSC 70 and HSP 70 in neural and non neural tissues of the piglet

David, J. C., Tanguay, R. M., & Grongnet, J. (2001) · Developmental Brain Research · doi:10.1016/s0165-3806(01)00143-2 · Cited by 14 · see citing works

Autoradiographic and in situ hybridization localization of corticotropin-releasing factor 1 and 2 receptors in nonhuman primate brain

S�nchez, M. M., Young, L. J., Plotsky, P. M., & Insel, T. R. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990607)408:3

The role of inflammation in perinatal brain injury

Hagberg, H., Mallard, C. E., Ferriero, D. M., Vannucci, S. J., Levison, S. W., Vexler, Z. S., & Gressèns, P. (2015) · Nature Reviews Neurology · doi:10.1038/nrneurol.2015.13 · Cited by 832 · see citing works

Autism risk factors: genes, environment, and gene-environment interactions

Chaste, P., & Leboyer, M. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.3/pchaste · Cited by 807 · see citing works

Epidemiology-driven neurodevelopmental animal models of schizophrenia

Meyer, U., & Feldon, J. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.10.018 · Cited by 366 · see citing works

Blockade of Nogo-66, Myelin-Associated Glycoprotein, and Oligodendrocyte Myelin Glycoprotein by Soluble Nogo-66 Receptor Promotes Axonal Sprouting and Recovery after Spinal Injury

Li, S., Liu, B. P., Budel, S., Li, M., Ji, B., Walus, L. R., Li, W., Jirik, A., Rabacchi, S. A., Choi, E., et al. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2828-04.2004 · Cited by 306 · see citing works

GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum

Fatemi, S. H., Stary, J. M., Earle, J. A., Araghi‐Niknam, M., & Eagan, E. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.02.017 · Cited by 300 · see citing works

Reelin signaling is impaired in autism

Fatemi, S. H., Snow, A. V., Stary, J. M., Araghi-Niknam, M., Reutiman, T. J., Lee, S., Brooks, A. I., & Pearce, D. A. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.12.018 · Cited by 280 · see citing works

Theories of schizophrenia: a genetic-inflammatory-vascular synthesis

Hanson, D. R., & Gottesman, I. I. (2005) · BMC Medical Genetics · doi:10.1186/1471-2350-6-7 · Cited by 274 · see citing works

Reelin glycoprotein: structure, biology and roles in health and disease

Fatemi, S. H. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001613 · Cited by 241 · see citing works

Paracrine and Autocrine Functions of Brain-derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in Brain-derived Endothelial Cells

Kim, H., Li, Q., Hempstead, B. L., & Madri, J. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404115200 · Cited by 206 · see citing works

Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia

Wang, F., Yang, Y., Yang, N., Chen, X., Huang, N.-X., Zhang, J., Wu, Y., Liu, Z., Gao, X., Li, T., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.017 · Cited by 201 · see citing works

Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: Neuropathology and behavioral deficits in single- and double-null mice

Pan, B., Fromholt, S., Hess, E. J., Crawford, T. O., Griffin, J. W., Sheikh, K. A., & Schnaar, R. L. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.04.017 · Cited by 195 · see citing works

Cortical neurogenesis enhanced by chronic perinatal hypoxia

Fagel, D. M., Ganat, Y. M., Silbereis, J. C., Ebbitt, T. B., Stewart, W. B., Jr., Heping Zhang, D., Ment, L. R., & Vaccarino, F. M. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.04.006 · Cited by 156 · see citing works

Regulation of intrinsic neuronal properties for axon growth and regeneration

Rossi, F., Gianola, S., & Corvetti, L. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.12.001 · Cited by 153 · see citing works

Impaired oligodendrocyte maturation in preterm infants: Potential therapeutic targets

van Tilborg, E., Heijnen, C. J., Benders, M. J. N. L., van Bel, F., Fleiss, B., Gressèns, P., & Nijboer, C. H. A. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.11.002 · Cited by 148 · see citing works

Understanding language and cognitive deficits in very low birth weight children

Ortiz‐Mantilla, S., Choudhury, N. A., Leevers, H. J., & BENASICH, A. A. (2008) · Developmental Psychobiology · doi:10.1002/dev.20278 · Cited by 134 · see citing works

Effect of chronic continuous or intermittent hypoxia and reoxygenation on cerebral capillary density and myelination

Kanaan, A., Farahani, R., Douglas, R. M., LaManna, J. C., & Haddad, G. G. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00535.2005 · Cited by 127 · see citing works

Intrauterine growth restriction affects the maturation of myelin

Tolcos, M., Bateman, E., O'Dowd, R., Markwick, R., Vrijsen, K., Rehn, A., & Rees, S. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.08.002 · Cited by 125 · see citing works

The effect of prenatal hypoxia on brain development: short‐ and long‐term consequences demonstrated in rodent models

Golan, H. M., & Huleihel, M. (2006) · Developmental Science · doi:10.1111/j.1467-7687.2006.00498.x · Cited by 112 · see citing works

Pathophysiology of cerebral palsy

Marret, S., Vanhulle, C., & Laquerrière, A. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52891-9.00016-6 · Cited by 112 · see citing works

Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

Krishnan, M. L., Van Steenwinckel, J., Schang, A.-L., Yan, J., Arnadottir, J., Le Charpentier, T., Csaba, Z., Dournaud, P., Cipriani, S., Auvynet, C., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-00422-w · Cited by 105 · see citing works

Hypoxia in the regulation of neural stem cells

Filippis, L. D., & Delia, D. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0723-5 · Cited by 105 · see citing works

Brain Imaging Studies of the Anatomical and Functional Consequences of Preterm Birth for Human Brain Development

Peterson, B. S. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1301.023 · Cited by 104 · see citing works

Modeling the neurovascular niche: implications for recovery from CNS injury.

Madri, J. A. (2009) · PubMed · Cited by 99 · see citing works

Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: a review of the evidence and putative mechanisms

Lieshout, R. J. V., & Voruganti, L. P. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0837 · Cited by 100 · see citing works

Sex Differences in a Hypoxia Model of Preterm Brain Damage

Mayoral, S. R., Omar, G., & Penn, A. A. (2009) · Pediatric Research · doi:10.1203/pdr.0b013e3181b1bc34 · Cited by 97 · see citing works

Hypoxia-Induced Developmental Delays of Inhibitory Interneurons Are Reversed by Environmental Enrichment in the Postnatal Mouse Forebrain

Komitova, M., Xenos, D., Salmaso, N., May Tran, K., Brand, T., Schwartz, M. L., Ment, L., & Vaccarino, F. M. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.5286-12.2013 · Cited by 88 · see citing works

Mouse intermittent hypoxia mimicking apnoea of prematurity: effects on myelinogenesis and axonal maturation

Cai, J., Tuong, C. M., Zhang, Y., Shields, C. B., Guo, G., Fu, H. Q., & Gozal, D. (2011) · The Journal of Pathology · doi:10.1002/path.2980 · Cited by 81 · see citing works

Prodeath or prosurvival: Two facets of hypoxia inducible factor-1 in perinatal brain injury

Chen, W., Ostrowski, R. P., Obenaus, A., & Zhang, J. H. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.10.016 · Cited by 80 · see citing works

Transient Hypoxemia Chronically Disrupts Maturation of Preterm Fetal Ovine Subplate Neuron Arborization and Activity

McClendon, E., Shaver, D. C., Degener-O’Brien, K., Gong, X., Nguyen, T. D., Hoerder‐Suabedissen, A., Molnár, Z., Mohr, C., Richardson, B. D., Rossi, D. J., et al. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2396-17.2017 · Cited by 75 · see citing works

In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus

Raman, L., Tkáč, I., Ennis, K., Georgieff, M., Rolf Gruetter, A., & Rao, R. (2005) · Developmental Brain Research · doi:10.1016/j.devbrainres.2005.02.013 · Cited by 73 · see citing works

Controversies in preterm brain injury

Penn, A. A., Gressèns, P., Fleiss, B., Back, S. A., & Gallo, V. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.10.012 · Cited by 73 · see citing works

Neonatal seizure classification: A fetal perspective concerning childhood epilepsy

Scher, M. S. (2006) · Epilepsy Research · doi:10.1016/j.eplepsyres.2005.11.020 · Cited by 70 · see citing works

Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity

Tillo, M., Ruhrberg, C., & Mackenzie, F. E. (2012) · Cell Adhesion & Migration · doi:10.4161/cam.22408 · Cited by 65 · see citing works

Long-Lasting Changes in DNA Methylation Following Short-Term Hypoxic Exposure in Primary Hippocampal Neuronal Cultures

Hartley, I., ElKhoury, F. F., Shin, J. H., Xie, B., Gu, X.-Q., Gao, Y., Zhou, D., & Haddad, G. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077859 · Cited by 64 · see citing works

Injury and repair in developing brain: Figure 1

Vaccarino, F. M., & Ment, L. R. (2004) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/adc.2003.043661 · Cited by 64 · see citing works

Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment

Chahboune, H., Ment, L. R., Stewart, W. B., Jr., Rothman, D. L., Vaccarino, F. M., Hyder, F., & Schwartz, M. L. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp068 · Cited by 63 · see citing works

Neonatal hypoxia suppresses oligodendrocyte Nogo-A and increases axonal sprouting in a rodent model for human prematurity

Weiss, J., Takizawa, B. T., McGee, A. W., Stewart, W. B., Jr., Heping Zhang, D., Ment, L. R., Schwartz, M. L., & Strittmatter, S. M. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.018 · Cited by 57 · see citing works

Global Gene Expression in the Developing Rat Brain After Hypoxic Preconditioning: Involvement of Apoptotic Mechanisms?

Gustavsson, M., Wilson, M. A., Mallard, C. E., Rousset, C. I., Johnston, M. V., & Hagberg, H. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180332be4 · Cited by 55 · see citing works

Global Gene Expression in the Immature Brain after Hypoxia-Ischemia

Hedtjärn, M., Mallard, C. E., Eklind, S., Brywe, K. G., & Hagberg, H. (2004) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/01.wcb.0000141558.40491.75 · Cited by 55 · see citing works

Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium

Stevenson, T. J., Trinh, T., Kogelschatz, C., Fujimoto, E., Lush, M. E., Piotrowski, T., Brimley, C., & Bonkowsky, J. L. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002638 · Cited by 53 · see citing works

Some of the experimental and clinical aspects of the effects of the maternal diabetes on developing hippocampus

Hami, J. (2015) · World Journal of Diabetes · doi:10.4239/wjd.v6.i3.412 · Cited by 51 · see citing works

Regulating axon growth within the postnatal central nervous system

Hu, F., & Strittmatter, S. M. (2004) · Seminars in Perinatology · doi:10.1053/j.semperi.2004.10.001 · Cited by 45 · see citing works

Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids

Boisvert, E. M., Means, R. E., Michaud, M., Madri, J. A., & Katz, S. G. (2019) · Cell Death &amp; Disease · doi:10.1038/s41419-019-1553-x · Cited by 45 · see citing works

The Effect of Growth Factors and Soluble Nogo-66 Receptor Protein on Transplanted Neural Stem/Progenitor Survival and Axonal Regeneration after Complete Transection of Rat Spinal Cord

Guo, X., Zahir, T., Mothe, A. J., Shoichet, M. S., Morshead, C. M., Katayama, Y., & Tator, C. H. (2012) · Cell Transplantation · doi:10.3727/096368911x612503 · Cited by 44 · see citing works

A neonatal mouse model of intermittent hypoxia associated with features of apnea in premature infants

Cai, J., Tuong, C. M., & Gozal, D. (2011) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2011.06.003 · Cited by 40 · see citing works

Neural plasticity and the K ennard principle: does it work for the preterm brain?

Bennet, L., van den Heuij, L. G., Dean, J. M., Drury, P. P., Wassink, G., & Gunn, A. J. (2013) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12135 · Cited by 41 · see citing works

Hypoxia and connectivity in the developing vertebrate nervous system

Bonkowsky, J. L., & Son, J. (2018) · Disease Models & Mechanisms · doi:10.1242/dmm.037127 · Cited by 40 · see citing works

NAP Enhances Neurodevelopment of Newborn Apolipoprotein E-Deficient Mice Subjected to Hypoxia

Rotstein, M. S., Bassan, H., Kariv, N., Speiser, Z., Harel, S., & Gozes, I. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.106898 · Cited by 40 · see citing works

Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons

Son, J., Keefe, M. D., Stevenson, T. J., Barrios, J. P., Anjewierden, S., Newton, J., Douglass, A. D., & Bonkowsky, J. L. (2016) · Scientific Reports · doi:10.1038/srep18734 · Cited by 39 · see citing works

Training-dependent cognitive advantage is suppressed at high altitude

Li, P., Zhang, G., You, H.-Y., Zheng, R., & Gao, Y. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.03.002 · Cited by 37 · see citing works

Multiple pharmacological and toxicological investigations on Tanacetum parthenium and Salix alba extracts: Focus on potential application as anti-migraine agents

di Giacomo, V., Ferrante, C., Ronci, M., Cataldi, A., Valerio, V. D., Rapino, M., Recinella, L., Chiavaroli, A., Leone, S., Vladimir‐Knežević, S., et al. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2019.110783 · Cited by 36 · see citing works

Pharmacologic stabilization of hypoxia-inducible transcription factors protects developing mouse brain from hypoxia-induced apoptotic cell death

Trollmann, R., Richter, M., Jung, S., Walkinshaw, G., & Brackmann, F. A. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.08.019 · Cited by 34 · see citing works

Pathophysiological and behavioral deficits in developing mice following rotational acceleration-deceleration traumatic brain injury

Wang, G., Zhang, Y. P., Gao, Z., Shields, L. B. E., Li, F., Chu, T., Lv, H., Moriarty, T. M., Xu, X., Yang, X., et al. (2018) · Disease Models & Mechanisms · doi:10.1242/dmm.030387 · Cited by 33 · see citing works

Hypoxia and myelination deficits in the developing brain

Singh, D. K., Ling, E., & Kaur, C. (2018) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2018.06.012 · Cited by 31 · see citing works

The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury

Rosner, J., Avalos, P., Acosta, F. L., Liu, J., & Drazin, D. G. (2012) · Stem Cells International · doi:10.1155/2012/826754 · Cited by 30 · see citing works

HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam

Trollmann, R., Schneider, J., Keller, S., Strasser, K., Wenzel, D., Rascher, W., Ogunshola, O. O., & Gassmann, M. (2008) · Brain Research · doi:10.1016/j.brainres.2007.12.069 · Cited by 29 · see citing works

The role of chronic hypoxia in the development of neurocognitive abnormalities in preterm infants with bronchopulmonary dysplasia

Raman, L., Georgieff, M., & Rao, R. (2006) · Developmental Science · doi:10.1111/j.1467-7687.2006.00500.x · Cited by 30 · see citing works

Mean cell spacing abnormalities in the neocortex of patients with schizophrenia

Casanova, M. F., de Zeeuw, L., Switala, A. E., Kreczmański, P., Korr, H., Ulfig, N., Heinsen, H., Steinbusch, H. W. M., & Schmitz, C. (2005) · Psychiatry Research · doi:10.1016/j.psychres.2004.11.004 · Cited by 30 · see citing works

Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat

Albrecht, J., Hanganu, I. L., Heck, N., & Luhmann, H. J. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04398.x · Cited by 28 · see citing works

Modeling the neurovascular niche: Murine strain differences mimic the range of responses to chronic hypoxia in the premature newborn

Li, Q., Michaud, M., Stewart, W. B., Jr., Schwartz, M. L., & Madri, J. A. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21597 · Cited by 27 · see citing works

Endothelial cells promote excitatory synaptogenesis and improve ischemia-induced motor deficits in neonatal mice

Wu, K., Lv, L.-L., Yu, L., Qian, C., & Sun, F. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.10.006 · Cited by 25 · see citing works

Global Gene Expression in the Immature Brain After Hypoxia-Ischemia

rn, M. H., Mallard, C. E., Eklind, S., Brywe, K. G., & Hagberg, H. (2004) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200412000-00002 · Cited by 26 · see citing works

Placental HIFs as markers of cerebral hypoxic distress in fetal mice

Trollmann, R., Strasser, K., Keller, S., Antoniou, X., Grenacher, B., Ogunshola, O. O., Dötsch, J., Rascher, W., & Gassmann, M. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00053.2008 · Cited by 26 · see citing works

Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling

Sun, C., Fu, J., Qu, Z., Jia, L., Li, D., Zhen, J., & Wang, W. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.617143 · Cited by 25 · see citing works

Neonatal Oxidative Stress Impairs Cortical Synapse Formation and GABA Homeostasis in Parvalbumin‐Expressing Interneurons

Scheuer, T., Endesfelder, S., Brinke, E. A. D., Bührer, C., & Schmitz, T. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/8469756 · Cited by 25 · see citing works

Stem cell therapies for perinatal brain injuries

Vawda, R., Woodbury, J., Covey, M. V., Levison, S. W., & Mehmet, H. (2007) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2007.02.003 · Cited by 26 · see citing works

Cannabidiol effectively prevents oxidative stress and stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) in an animal model of global hypoxia

Kletkiewicz, H., Wojciechowski, M. S., & Rogalska, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-66599-5 · Cited by 23 · see citing works

Dysmaturation of Somatostatin Interneurons Following Umbilical Cord Occlusion in Preterm Fetal Sheep

Ardalan, M., Svedin, P., Baburamani, A. A., Supramaniam, V. G., Ek, C. J., Hagberg, H., & Mallard, C. E. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00563 · Cited by 23 · see citing works

Brain Organoids and Assembloids—From Disease Modeling to Drug Discovery

Ajongbolo, A. O., & Langhans, S. A. (2025) · Cells · doi:10.3390/cells14110842 · Cited by 24 · see citing works

Sustained hypoxia modulates mitochondrial DNA content in the neonatal rat brain

Lee, H. M., Greeley, G. H., & Englander, E. W. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.11.005 · Cited by 22 · see citing works

Vision and the hypothalamus

Trachtman, J. N. (2010) · Optometry · doi:10.1016/j.optm.2009.07.016 · Cited by 22 · see citing works

Strain Differences in Behavioral and Cellular Responses to Perinatal Hypoxia and Relationships to Neural Stem Cell Survival and Self-Renewal

Li, Q., Liu, J., Michaud, M., Schwartz, M. L., & Madri, J. A. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.090354 · Cited by 21 · see citing works

Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation

Schneider, C., Krischke, G., Rascher, W., Gassmann, M., & Trollmann, R. (2011) · Brain and Development · doi:10.1016/j.braindev.2011.07.006 · Cited by 20 · see citing works

NAP prevents hippocampal oxidative damage in neonatal rats subjected to hypoxia-induced seizures

Greggio, S., Rosa, R. M., Dolganov, A., de Oliveira, I. M., Menegat, F. D., Henriques, J. A. P., & DaCosta, J. C. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.08.008 · Cited by 19 · see citing works

Hypoxia Delays Oligodendrocyte Progenitor Cell Migration and Myelin Formation by Suppressing Bmp2b Signaling in Larval Zebrafish

Yang, L.-Q., Chen, M., Zhang, J.-L., Ren, D., & Hu, B. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00348 · Cited by 18 · see citing works

Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain

Schneider, C., Krischke, G., Keller, S., Walkinshaw, G., Arend, M., Rascher, W., Gassmann, M., & Trollmann, R. (2009) · Brain Research · doi:10.1016/j.brainres.2009.05.023 · Cited by 18 · see citing works

Development of smooth pursuit eye movements in very prematurely born infants: 2. The low‐risk subgroup

Grönqvist, H., Brodd, K. S., & Rosander, K. (2011) · Acta Paediatrica · doi:10.1111/j.1651-2227.2011.02247.x · Cited by 17 · see citing works

Transcriptomic analysis reveals transgenerational effect of hypoxia on the neural control of testicular functions

Lai, K. P., Li, J., Wang, S. Y., Wan, T., Chan, T., Lui, W., Au, D. W. T., Wu, R. S. S., & Kong, R. Y. C. (2017) · Aquatic Toxicology · doi:10.1016/j.aquatox.2017.12.005 · Cited by 17 · see citing works

Gestational diabetes is associated to the development of brain insulin resistance in the offspring

Sousa, R. A. L. D. (2018) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-018-0618-1 · Cited by 17 · see citing works

Acute sublethal global hypoxia induces transient increase of GAP‐43 immunoreactivity in the striatum of neonatal rats

Valdez, S. R., Patterson, S. I., Ezquer, M., Torrecilla, N. M., Lama, M. C., & Seltzer, A. M. (2006) · Synapse · doi:10.1002/syn.20353 · Cited by 15 · see citing works

Intermittent hypoxia in a mouse model of apnea of prematurity leads to a retardation of cerebellar development and long-term functional deficits

Leroux, S., Rodriguez-Duboc, A., Arabo, A., Basille, M., Vaudry, D., & Burel, D. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00869-5 · Cited by 12 · see citing works

Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish

Son, J., Stevenson, T. J., Bowles, M. D., Scholl, E. A., & Bonkowsky, J. L. (2020) · eNeuro · doi:10.1523/eneuro.0355-19.2020 · Cited by 11 · see citing works

Neonatal Hypertonia: II. Differential Diagnosis and Proposed Neuroprotection

Scher, M. S. (2008) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2008.09.009 · Cited by 11 · see citing works

The Neurodevelopmental Model of Schizophrenia: Updated

Bearden, C. E., MEYER, S. E., Loewy, R. L., Niendam, T. A., & Cannon, T. D. (2015) · Wiley eBooks · doi:10.1002/9780470939406.ch14 · Cited by 10 · see citing works

Caffeine: The Story beyond Oxygen-Induced Lung and Brain Injury in Neonatal Animal Models—A Narrative Review

Endesfelder, S. (2024) · Antioxidants · doi:10.3390/antiox13091076 · Cited by 10 · see citing works

Complex‐environment rearing prevents prenatal hypoxia‐induced deficitsin hippocampal cellular mechanisms necessary for memory consolidationin the adult Wistar rat

Foley, A., Murphy, K. J., & Regan, C. M. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20641 · Cited by 10 · see citing works

Modulation of Sox10, HIF-1α, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult

Li, Q., Tsuneki, M., Krauthammer, M. O., Couture, R., Schwartz, M. L., & Madri, J. A. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.05.016 · Cited by 9 · see citing works

Modeling the Neurovascular Niche: Unbiased Transcriptome Analysis of the Murine Subventricular Zone in Response to Hypoxic Insult

Li, Q., Canosa, S., Flynn, K. M., Michaud, M., Krauthammer, M. O., & Madri, J. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076265 · Cited by 9 · see citing works

Unraveling the Genetic and Environmental Risk Factors of Autism Spectrum Disorder Through a Case‐Control Study in Armenia

Mkhitaryan, M., Avetisyan, T., Yeritsyan, H., Harutyunyan, H. A., & Yenkoyan, K. B. (2025) · Health Science Reports · doi:10.1002/hsr2.70801 · Cited by 9 · see citing works

Physiology of oligodendroglia

Butt, A. M., Niu, J., Yi, C., & Verkhratsky, A. (2026) · Physiological Reviews · doi:10.1152/physrev.00023.2025 · Cited by 7 · see citing works

Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells

Bence, M., Kereszturi, É., Mózes, V., Sasvári‐Székely, M., & Keszler, G. (2009) · BMC Neuroscience · doi:10.1186/1471-2202-10-92 · Cited by 7 · see citing works

Oxytocin Regulated Neuroinflammation through OTR/Mitochondria Mediated Pathway to Improve Hypoxia-Induced Brain Injury

Yang, X., Li, K., Chen, L., Wang, L., Wang, X., Lu, K., Bai, Y., Hou, Y., Hou, J., Wang, C., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05061-7 · Cited by 6 · see citing works

The role of endothelial HIF-1 αin the response to sublethal hypoxia in C57BL/6 mouse pups

Li, Q., Michaud, M., Park, C., Huang, Y., Couture, R., Girodano, F., Schwartz, M. L., & Madri, J. A. (2017) · Laboratory Investigation · doi:10.1038/labinvest.2016.154 · Cited by 6 · see citing works

The Role of Reelin in Etiology and Treatment of Psychiatric Disorders

Fatemi, S. H., Reutiman, T. J., & Folsom, T. D. (2008) · Springer eBooks · doi:10.1007/978-0-387-76761-1_22 · Cited by 6 · see citing works

A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions

Dai, W., Nian, X., Zhou, Z., Du, A., Liu, Q., Jia, S., Yan, L., Li, D., Lu, X., Zhu, Y., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115467 · Cited by 5 · see citing works

Temporal Dysynchrony in brain connectivity gene expression following hypoxia

Milash, B. A., Gao, J., Stevenson, T. J., Son, J., Dahl, T. M., & Bonkowsky, J. L. (2016) · BMC Genomics · doi:10.1186/s12864-016-2638-x · Cited by 5 · see citing works

Pathophysiology of Perinatal Hypoxia-Ischemia and the Prospects for Repair from Endogenous and Exogenous Stem Cells

Covey, M. V., & Levison, S. W. (2006) · NeoReviews · doi:10.1542/neo.7-7-e353 · Cited by 5 · see citing works

Consequences of oxygen deprivation on myelination and sex-dependent alterations

Fabres, R., Cardoso, D. S., Aragon, B., Arruda, B. P., Martins, P., Ikebara, J. M., Drobyshevsky, A., Kihara, A., de Fraga, L. D., Netto, C., et al. (2023) · Molecular and cellular neurosciences · doi:10.1016/j.mcn.2023.103864 · Cited by 4 · see citing works

Hypoxia-induced hypomyelination in the developing brain is mammalian target of rapamycin-4E-binding protein-1 signaling dependent

Bilali, F., Kumar, P., Feerick, J., Berezin, S. H., & Farahani, R. (2008) · Neuroreport · doi:10.1097/wnr.0b013e3282fa701c · Cited by 3 · see citing works

Postnatal Hypoxia and the Developing Brain: Cellular and Molecular Mechanisms of Injury

Douglas, R. M. (2009) · Contemporary clinical neuroscience · doi:10.1007/978-1-60327-579-8_13 · Cited by 3 · see citing works

Responses of Rat Brain Interneuronal Synapses to Hypoxia in the Early Neonatal Period

Otellin, V. A., Хожай, Л. И., & Shishko, T. T. (2014) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-014-0029-9 · Cited by 3 · see citing works

[Reactions of the interneuronal synapses of rat brain to hypoxia during the early postnatal period].

Otellin, V. A., Khozhai, L. I., & Shishko, T. T. (2014) · PubMed · Cited by 1 · see citing works

Transient sublethal hypoxia in neonatal rats causes reduced dendritic spines, aberrant synaptic plasticity, and impairments in memory

Tang, W., Xin, X., O’Connor, M. G., Zhang, N., Lai, B., Man, H., Xie, Y., & Wei, Y. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24652 · Cited by 8 · see citing works

Transient Hypoxemia Disrupts Anatomical and Functional Maturation of Preterm Fetal Ovine CA1 Pyramidal Neurons

McClendon, E., Wang, K., Degener-O’Brien, K., Hagen, M. W., Gong, X., Nguyen, T. D., Wu, W., Maylie, J., & Back, S. A. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.1364-19.2019 · Cited by 36 · see citing works

Mild Neonatal Hypoxia Targets Synaptic Maturation, Disrupts Adult Hippocampal Learning and Memory, and Is Associated with CK2-Mediated Loss of Synaptic Calcium-Activated Potassium Channel KCNN2 Activity

Riddle, A., Srivastava, T., Wang, K., Téllez, E. A., O’Neill, H., Gong, X., O’Niel, A., Bell, J. A., Raber, J., Lattal, M., et al. (2026) · Journal of Neuroscience · doi:10.1523/jneurosci.1643-25.2026