The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Regulation by Calcium of In Vivo Synthesis of 1,25-Dihydroxycholecalciferol and 21,25-Dihydroxycholecalciferol
Open accessAbstract
Tritiated 1,25-dihydroxycholecalciferol accumulates in several tissues, to an extent that varies with dietary calcium content, 12 hr after the administration of 325 pmoles of tritiated 25-hydroxycholecalciferol to rats. As the dietary and serum calcium concentrations increase, the amount of 1,25-dihydroxycholecalciferol is diminished and the concentration of 21,25-dihydroxycholecalciferol increases. This correlation is especially evident in rats given vitamin D 3 . In vitamin D-deficient rats, the repression of 1,25-dihydroxycholecalciferol formation occurs with a diet containing 3% calcium and 20% lactose. The results suggest that the production of 1,25-dihydroxycholecalciferol, believed to be the metabolically active form of vitamin D in the intestine, is responsible for the adaptation of calcium absorption to low dietary concentrations of calcium.
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Citations
Cites
Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite
FRASER, D. R., & KODICEK, E. (1970) · Nature · doi:10.1038/228764a0 · Cited by 1,281
DeLuca, H. F., Holick, M. F., Schnoes, H. K., Suda, T., & Cousins, R. J. (1971) · Biochemistry · doi:10.1021/bi00790a023 · Cited by 504
Self-citationIdentification of 1,25-Dihydroxycholecalciferol, a New Kidney Hormone controlling Calcium Metabolism
LAWSON, D. E. M., FRASER, D. R., KODICEK, E., MORRIS, H. R., & WILLIAMS, D. H. (1971) · Nature · doi:10.1038/230228a0 · Cited by 498
Biological Activity of 25-Hydroxyergocalciferol in Rats
Suda, T., DeLuca, H. F., & Tanaka, Y. (1970) · The Journal of Nutrition · doi:10.1093/jn/100.9.1049 · Cited by 358
Self-citationPhysiology of Calcium Metabolism
Nicolaysen, R., Eeg-Larsen, N., & Malm, O. J. (1953) · Physiological Reviews · doi:10.1152/physrev.1953.33.3.424 · Cited by 320
Biologically active metabolite of vitamin D3 from bone, liver, and blood serum
Lund, J., & DeLuca, H. F. (1966) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38950-1 · Cited by 305
Self-citationBiological activity 1,25-dihydroxycholecalciferol
DeLuca, H. F., Omdahl, J., Holick, M., Suda, T., & Tanaka, Y. (1971) · Biochemistry · doi:10.1021/bi00791a022 · Cited by 279
Self-citationHolick, M. F., Schnoes, H. K., & DeLuca, H. F. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.4.803 · Cited by 277
Self-citationHOLICK, M. F., & DeLUCA, H. F. (1971) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39495-5 · Cited by 258
Self-citationVitamin D: A Cholecalciferol Metabolite Highly Active in Promoting Intestinal Calcium Transport
Myrtle, J. F., & Norman, A. W. (1971) · Science · doi:10.1126/science.171.3966.79 · Cited by 210
Cited by
Regulation of 25-Hydroxycholecalciferol-1-Hydroxylase Activity in Kidney by Parathyroid Hormone
FRASER, D. R., & KODICEK, E. (1973) · Nature New Biology · doi:10.1038/newbio241163a0 · Cited by 527
The Prophylactic Portacaval Shunt
(1972) · The Lancet · doi:10.1016/s0140-6736(72)91163-4 · Cited by 373
Krall, E. A., Sahyoun, N., Tannenbaum, S., Dallal, G. E., & Dawson-Hughes, B. (1989) · New England Journal of Medicine · doi:10.1056/nejm198912283212602 · Cited by 345
1α,25-Dihydroxycholecalciferol Receptors in Intestine
Brumbaugh, P. F., & Haussler, M. R. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42968-2 · Cited by 278
History of the discovery of vitamin D and its active metabolites
DeLuca, H. F. (2014) · BoneKEy Reports · doi:10.1038/bonekey.2013.213 · Cited by 249
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Metadata
- Authors
- Boyle, I. T., Gray, R. W., & Deluca, H. F.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1971-09
- Volume
- 68
- Issue
- 9
- Pages
- 2131-2134
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1995946436
- Cited by
- 444
- References
- 13
- FWCI
- 45.01
- Type
- journal article
- Language
- en
- Open access
- green
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- Boyle, I. T., Gray, R. W., & Deluca, H. F. (1971). Regulation by Calcium of In Vivo Synthesis of 1,25-Dihydroxycholecalciferol and 21,25-Dihydroxycholecalciferol. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.68.9.2131
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
