Nonprotein amino acids from spark discharges and their comparison with the Murchison meteorite amino acids
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All the nonprotein amino acids found in the Murchison meteorite are products of the action of electric discharge on a mixture of methane, nitrogen, and water with traces of ammonia. These amino acids include α-amino- n -butyric acid, α-aminoisobutyric acid, norvaline, isovaline, pipecolic acid, β-alanine, β-amino-n-butyric acid, β-aminoisobutyric acid, γ-aminobutyric acid, sarcosine, N -ethylglycine, and N -methylalanine. In addition, norleucine, alloisoleucine, N -propylglycine, N -isopropylglycine, N -methyl-β-alanine, N -ethyl-β-alanine α,β-diaminopropionic acid, isoserine, α,γ-diaminobutyric acid, and α-hydroxy-γ-aminobutyric acid are produced by the electric discharge, but have not been found in the meteorite.
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Carbonaceous meteorites contain a myriad of organic compounds divided between a soluble fraction and an insoluble organic matter (IOM) phase consisting of intractable complex macromolecular organic material.
“Carbonaceous meteorites contain a myriad of organic compounds divided between a soluble fraction and an insoluble organic matter (IOM) phase consisting of intractable complex macromolecular organic material.”
From Polyesters as a Model System for Building Primitive Biologies from Non-Biological Prebiotic Chemistry (2020) · cites this paper as [11]
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Kauffman, S. A., Jelenfi, D. P., & Vattay, G. (2019) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2019.110097 · Cited by 23 · see citing works
A quantitative investigation of the chemical space surrounding amino acid alphabet formation
Lu, Y., & Freeland, S. J. (2007) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2007.10.007 · Cited by 23 · see citing works
Mellersh, A. R. (1993) · Origins of Life and Evolution of Biospheres · doi:10.1007/bf01581903 · Cited by 23 · see citing works
Characterization of oil shales by laser pyrolysis-gas chromatography
Hanson, R. L., Vanderborgh, N. E., & Brookins, D. G. (1975) · Analytical Chemistry · doi:10.1021/ac60352a015 · Cited by 23 · see citing works
An Experimental and Theoretical Investigation of HCN Production in the Hadean Earth Atmosphere
Pearce, B. K. D., He, C., & Hörst, S. M. (2022) · ACS Earth and Space Chemistry · doi:10.1021/acsearthspacechem.2c00138 · Cited by 21 · see citing works
Guttenberg, N., Chen, H., Mochizuki, T., & Cleaves, H. J. (2021) · Life · doi:10.3390/life11030234 · Cited by 20 · see citing works
- Authors
- Wolman, Y., Haverland, W. J., & Miller, S. L.
- Affiliations
- University of California San Diego (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 1972-04
- Volume
- 69
- Issue
- 4
- Pages
- 809-811
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC426569
- OpenAlex
- W2006555521
- Cited by
- 198
- References
- 11
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 10 · 2023: 3 · 2022: 7 · 2021: 5 · 2020: 7 · 2019: 5 · 2018: 5 · 2017: 7 · 2016: 4 · 2015: 1 · 2014: 5 · 2013: 4 · 2012: 6
- FWCI
- 12.33
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Astro and Planetary Science
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Space Science and Extraterrestrial Life
- Keywords
- nonprotein amino acids, Murchison meteorite, spark discharge, electric discharge synthesis, amino acid synthesis, prebiotic chemistry, GABA, N-methylalanine, pipecolic acid, beta-alanine, meteoritic amino acids
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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