The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.
Open accessAbstract
We have determined the sequence of the DNA of a germ-line gene for the variable region of a mouse immunoglobulin light chain, the VlambdaII gene. The sequence confirms that the variable region gene lies on the DNA separated from the constant region. Hypervariable region codons appear in the germ-line sequence. A sequence for the hydrophobic leader, 19 amino acids that are cleaved from the amino terminus of the protein, appears near, but not continuous with, the light chain structural sequence: most of the leader sequence is separated from the rest of the gene by 93 bases of untranslated DNA.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A new method for sequencing DNA.
Maxam, A. M., & Gilbert, W. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.2.560 · Cited by 7,922
Self-citationBlobel, G., & Dobberstein, B. (1975) · The Journal of cell biology · doi:10.1083/jcb.67.3.835 · Cited by 3,002
Spliced segments at the 5′ terminus of adenovirus 2 late mRNA
Berget, S. M., Moore, C., & Sharp, P. A. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3171 · Cited by 1,413
Wu, T. T., & Kabat, E. A. (1970) · The Journal of Experimental Medicine · doi:10.1084/jem.132.2.211 · Cited by 1,340
An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA
Chow, L. T., Gelinas, R. E., Broker, T. R., & Roberts, R. J. (1977) · Cell · doi:10.1016/0092-8674(77)90180-5 · Cited by 1,234
Blobel, G., & Dobberstein, B. (1975) · The Journal of cell biology · doi:10.1083/jcb.67.3.852 · Cited by 1,169
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.
Hozumi, N., & Tonegawa, S. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.10.3628 · Cited by 759
Self-citationA Possible Precursor of Immunoglobulin Light Chains
MILSTEIN, C., BROWNLEE, G. G., HARRISON, T. M., & MATHEWS, M. B. (1972) · Nature New Biology · doi:10.1038/newbio239117a0 · Cited by 603
Variability in the Lambda Light Chain Sequences of Mouse Antibody
WEIGERT, M. G., CESARI, I. M., YONKOVICH, S. J., & COHN, M. (1970) · Nature · doi:10.1038/2281045a0 · Cited by 553
Ovalbumin gene is split in chicken DNA
Breathnach, R., Mandel, J. L., & Chambon, P. (1977) · Nature · doi:10.1038/270314a0 · Cited by 396
Cited by
Somatic generation of antibody diversity
Tonegawa, S. (1983) · Nature · doi:10.1038/302575a0 · Cited by 4,005
Self-citationKozak, M. (1981) · Nucleic Acids Research · doi:10.1093/nar/9.20.5233 · Cited by 1,242
Breathnach, R., Benoist, C., O'Hare, K., Gannon, F., & Chambon, P. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.10.4853 · Cited by 1,123
Wahl, G. M., Padgett, R. A., & Stark, G. R. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86945-4 · Cited by 451
Length distribution of CDRH3 in antibodies
Wu, T. T., Johnson, G., & Kabat, E. A. (1993) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.340160102 · Cited by 284
Metadata
- Authors
- Tonegawa, S., Maxam, A. M., Tizard, R., Bernard, O., & Gilbert, W.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1978-03
- Volume
- 75
- Issue
- 3
- Pages
- 1485-1489
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1982064764
- Cited by
- 414
- References
- 18
- FWCI
- 90.36
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. https://app.cochat.ai/papers/10.1073/pnas.75.3.1485
- The paper
- Tonegawa, S., Maxam, A. M., Tizard, R., Bernard, O., & Gilbert, W. (1978). Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.75.3.1485
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
