The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Cloning and sequence analysis of cDNA for human renin precursor.
Open accessAbstract
The primary structure of human renin precursor has been deduced from its cDNA sequence. A library of cDNA clones was constructed from human kidney poly(A)+ RNA by applying the vector/primer method of Okayama and Berg. The library was screened for human renin sequences by hybridization with the previously cloned mouse renin cDNA. Of the 240,000 colonies screened, 35 colonies that were positive for hybridization were isolated. Two recombinant plasmids containing long inserts of about 1,300 and 1,600 base pairs were selected for sequence analysis. The amino acid sequence predicted from the cDNA sequence shows that the human renin precursor consists of 406 amino acids with a pre and a pro segment carrying 20 and 46 amino acids, respectively. A high degree of sequence homology was found upon comparison of the mouse and human renins. Close similarities were also observed in the primary structures of renin and aspartyl proteinases that have known three-dimensional structures, suggesting a similar tertiary structure for renin.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,725
[57] Sequencing end-labeled DNA with base-specific chemical cleavages
Maxam, A. M., & Gilbert, W. (1980) · Methods in Enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 14,315
Aviv, H., & Leder, P. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1408 · Cited by 6,751
3′ Non-coding region sequences in eukaryotic messenger RNA
Proudfoot, N. J., & Brownlee, G. G. (1976) · Nature · doi:10.1038/263211a0 · Cited by 2,968
McMaster, G. K., & Carmichael, G. G. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.11.4835 · Cited by 2,348
Alwine, J. C., Kemp, D. J., & Stark, G. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5350 · Cited by 2,236
Renin-angiotensin system: biochemistry and mechanisms of action.
Peach, M. J. (1977) · Physiological Reviews · doi:10.1152/physrev.1977.57.2.313 · Cited by 1,378
High-Efficiency Cloning of Full-Length cDNA
Okayama, H., & Berg, P. (1982) · Molecular and Cellular Biology · doi:10.1128/mcb.2.2.161-170.1982 · Cited by 1,267
Kozak, M. (1981) · Nucleic Acids Research · doi:10.1093/nar/9.20.5233 · Cited by 1,242
Structural evidence for gene duplication in the evolution of the acid proteases
Tang, J., James, M. N. G., Hsu, I. N., Jenkins, J. A., & Blundell, T. L. (1978) · Nature · doi:10.1038/271618a0 · Cited by 408
Cited by
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
Yamamoto, T., Ikawa, S., Akiyama, T., Semba, K., Nomura, N., Miyajima, N., Saito, T., & Toyoshima, K. (1986) · Nature · doi:10.1038/319230a0 · Cited by 1,204
Classical Renin‐Angiotensin System in Kidney Physiology
Sparks, M. A., Crowley, S. D., Gurley, S. B., Mirotsou, M., & Coffman, T. M. (2014) · Comprehensive Physiology · doi:10.1002/cphy.c130040 · Cited by 521
Low nucleotide diversity in man.
Li, W. H., & Sadler, L. A. (1991) · Genetics · doi:10.1093/genetics/129.2.513 · Cited by 501
Antihypertensive Peptides from Food Proteins
Aluko, R. E. (2015) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022814-015520 · Cited by 383
Evolution in the structure and function of aspartic proteases
Tang, J., & Wong, R. N. S. (1987) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240330106 · Cited by 302
Metadata
- Authors
- Imai, T., Miyazaki, H., Hirose, S., Hori, H., Hayashi, T., Kageyama, R., Ohkubo, H., Nakanishi, S., & Murakami, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1983-12
- Volume
- 80
- Issue
- 24
- Pages
- 7405-7409
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1992589321
- Cited by
- 271
- References
- 15
- FWCI
- 15.37
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Cloning and sequence analysis of cDNA for human renin precursor. https://app.cochat.ai/papers/10.1073/pnas.80.24.7405
- The paper
- Imai, T., Miyazaki, H., Hirose, S., Hori, H., Hayashi, T., Kageyama, R., Ohkubo, H., Nakanishi, S., & Murakami, K. (1983). Cloning and sequence analysis of cDNA for human renin precursor. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.80.24.7405
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
