The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Hebbian synapses in hippocampus.
Open accessAbstract
A combination of current- and voltage-clamp techniques applied to hippocampal brain slices was used to evaluate the role of postsynaptic electrogenesis in the induction of associative synaptic enhancement. In accordance with Hebb's postulate for learning, repetitive postsynaptic spiking enabled enhancement in just those synapses that were eligible to change by virtue of concurrent presynaptic activity. However, the essential postsynaptic electrogenic event that controlled the enhancement was shown to involve biophysical processes that were unknown when Hebb formulated his neurophysiological postulate. The demonstrated spatiotemporal specificity of this pseudo-Hebbian conjunctive mechanism can account qualitatively for the known neurophysiological properties of associative long-term potentiation in these synapses, which in turn can explain the "cooperativity" requirement for long-term potentiation.
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Citations
Cites
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Intracellular injections of EGTA block induction of hippocampal long-term potentiation
Lynch, G., Larson, J., Kelso, S., Barrionuevo, G., & Schottler, F. (1983) · Nature · doi:10.1038/305719a0 · Cited by 1,116
Self-citationLevy, W. B., & Steward, O. (1983) · Neuroscience · doi:10.1016/0306-4522(83)90010-6 · Cited by 766
A Physiological Mechanism for Hebb's Postulate of Learning
Stent, G. S. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.4.997 · Cited by 710
Synaptic enhancement in fascia dentata: Cooperativity among coactive afferents
McNaughton, B. L., Douglas, R. M., & Goddard, G. V. (1978) · Brain Research · doi:10.1016/0006-8993(78)90030-6 · Cited by 647
Synapses as associative memory elements in the hippocampal formation
Levy, W. B., & Steward, O. (1979) · Brain Research · doi:10.1016/0006-8993(79)91003-5 · Cited by 560
Facilitated induction of hippocampal long-lasting potentiation during blockade of inhibition
Wigström, H., & Gustafsson, B. (1983) · Nature · doi:10.1038/301603a0 · Cited by 354
Neural Assemblies: An Alternative Approach to Artificial Intelligence
Palm, G. (1982) · MPG.PuRe (Max Planck Society) · Cited by 301
WIGSTRÖM, H., GUSTAFSSON, B., HUANG, Y. ‐., & ABRAHAM, W. C. (1986) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1986.tb07822.x · Cited by 284
Associative long-term potentiation in hippocampal slices.
Barrionuevo, G., & Brown, T. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.23.7347 · Cited by 273
Self-citation
Cited by
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
Markram, H., Lübke, J., Frotscher, M., & Sakmann, B. (1997) · Science · doi:10.1126/science.275.5297.213 · Cited by 3,832
CORTICAL PLASTICITY: From Synapses to Maps
Buonomano, D. V., & Merzenich, M. M. (1998) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.21.1.149 · Cited by 2,083
Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP
Malinow, R., Schulman, H., & Tsien, R. W. (1989) · Science · doi:10.1126/science.2549638 · Cited by 1,325
A Synaptically Controlled, Associative Signal for Hebbian Plasticity in Hippocampal Neurons
Magee, J. C., & Johnston, D. (1997) · Science · doi:10.1126/science.275.5297.209 · Cited by 1,315
Metadata
- Authors
- Kelso, S. R., Ganong, A. H., & Brown, T. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1986-07
- Volume
- 83
- Issue
- 14
- Pages
- 5326-5330
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2047468613
- Cited by
- 555
- References
- 24
- FWCI
- 13.30
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
