The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.
Open accessAbstract
Antisera to recombinant human immunodeficiency virus (HIV) proteins containing the entire envelope, gp160, or the central portion of the envelope, PB1, can inhibit fusion of virally infected cells in culture. This fusion inhibition is HIV-variant specific--that is, anti-gp160-IIIB inhibits fusion of isolate HTLV-IIIB-infected cells but not of isolate HTLV-IIIRF-infected cells. Both anti-gp160 and anti-PB1 are completely blocked in fusion inhibition activity by the addition of PB1 protein. A 24-amino acid peptide (RP135, amino acids 307-330) completely blocks fusion inhibition activity of both antisera and also blocks the activity of serum from a chimpanzee infected with HTLV-IIIB. Thus, the principal epitope that elicits fusion-inhibiting antibodies is located in the central portion of gp120.
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Cites
Starcich, B. R., Hahn, B. H., Shaw, G. M., McNeely, P. D., Modrow, S., Wolf, H., Parks, E. S., Parks, W. P., Josephs, S. F., Gallo, R. C., et al. (1986) · Cell · doi:10.1016/0092-8674(86)90778-6 · Cited by 767
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Cited by
Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling
Uversky, V. N., Oldfield, C. J., & Dunker, A. K. (2005) · Journal of Molecular Recognition · doi:10.1002/jmr.747 · Cited by 847
Thali, M., Moore, J. P., Furman, C., Charles, M., Ho, D. D., Robinson, J., & Sodroski, J. (1993) · Journal of Virology · doi:10.1128/jvi.67.7.3978-3988.1993 · Cited by 616
Wyatt, R., Moore, J., Accola, M., Desjardin, E., Robinson, J., & Sodroski, J. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5723-5733.1995 · Cited by 417
Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1
Javaherian, K., Langlois, A. J., LaRosa, G. J., Profy, A. T., Bolognesi, D. P., Herlihy, W. C., Putney, S. D., & Matthews, T. J. (1990) · Science · doi:10.1126/science.1703322 · Cited by 353
Self-citationRadford, A. D., Willoughby, K., Dawson, S., McCracken, C., & Gaskell, R. M. (1999) · Journal of Virology · doi:10.1128/jvi.73.10.8496-8502.1999 · Cited by 80
Metadata
- Authors
- Rusche, J. R., Javaherian, K., McDanal, C., Petro, J., Lynn, D. L., Grimaila, R., Langlois, A., Gallo, R. C., Arthur, L. O., & Fischinger, P. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1988-05
- Volume
- 85
- Issue
- 9
- Pages
- 3198-3202
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2137966586
- Cited by
- 620
- References
- 1
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120. https://app.cochat.ai/papers/10.1073/pnas.85.9.3198
- The paper
- Rusche, J. R., Javaherian, K., McDanal, C., Petro, J., Lynn, D. L., Grimaila, R., Langlois, A., Gallo, R. C., Arthur, L. O., & Fischinger, P. J. (1988). Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.85.9.3198
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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