The DOI matches its Crossref record.
De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.
Open accessAbstract
The 89-kDa cell surface glycoprotein, P3.58, is detectable on advanced human melanomas in situ but not on benign melanocytes or early melanomas. cDNA cloning of P3.58 from melanoma cells was accomplished by screening a lambda zap expression vector library with monoclonal antibodies produced against the denatured antigen. Nucleotide sequencing of the clones revealed that P3.58 is identical to the intercellular-adhesion molecule 1. No qualitative differences in P3.58 mRNA species could be seen between melanoma cells and hematopoietic cells and no differences in gene organization were observed between peripheral blood leukocytes and melanoma cells. Inspection of the deduced amino acid sequence of P3.58 indicated the presence of the consensus sequence characteristic for complement-binding proteins. The acquisition of this cell-adhesion molecule during the process of tumor progression is speculated to contribute to the development of metastasis in melanoma.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Intercellular adhesion molecule-1
van de Stolpe, A., & van der Saag, P. T. (1996) · Journal of Molecular Medicine · doi:10.1007/bf00202069 · Cited by 802
Adhesion, migration and communication in melanocytes and melanoma
Haass, N. K., Smalley, K. S. M., Li, L., & Herlyn, M. (2005) · Pigment Cell Research · doi:10.1111/j.1600-0749.2005.00235.x · Cited by 388
D'Urso, C. M., Wang, Z. G., Cao, Y., Tatake, R., Zeff, R. A., & Ferrone, S. (1991) · Journal of Clinical Investigation · doi:10.1172/jci114984 · Cited by 309
Overexpression of the CD155 gene in human colorectal carcinoma
Masson, D., Jarry, A., Baury, B., Blanchardie, P., Laboisse, C., Lustenberger, P., & Denis, M. G. (2001) · Gut · doi:10.1136/gut.49.2.236 · Cited by 286
nmb, a novel gene, is expressed in low‐metastatic human melanoma cell lines and xenografts
Weterman, M. A. J., Ajubi, N., van Dinter, I. M. R., Degen, W. G. J., van Muijen, G. N. P., Ruiter, D. J., & Bloemers, H. P. J. (1995) · International Journal of Cancer · doi:10.1002/ijc.2910600111 · Cited by 256
Metadata
- Authors
- Johnson, J. P., Stade, B. G., Holzmann, B., Schwäble, W., & Riethmüller, G.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1989-01
- Volume
- 86
- Issue
- 2
- Pages
- 641-644
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2019405807
- Cited by
- 359
- References
- 0
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis. https://app.cochat.ai/papers/10.1073/pnas.86.2.641
- The paper
- Johnson, J. P., Stade, B. G., Holzmann, B., Schwäble, W., & Riethmüller, G. (1989). De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.86.2.641
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
