The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation.
Open accessAbstract
Brain lactate concentration is usually assumed to be stable except when pathologic conditions cause a mismatch between glycolysis and respiration. Using newly developed 1H NMR spectroscopic techniques that allow measurement of lactate in vivo, we detected lactate elevations of 0.3-0.9 mM in human visual cortex during physiologic photic stimulation. The maximum rise appeared in the first few minutes; thereafter lactate concentration declined while stimulation continued. The results are consistent with a transient excess of glycolysis over respiration in the visual cortex, occurring as a normal response to stimulation in the physiologic range.
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Cites
Nonoxidative Glucose Consumption During Focal Physiologic Neural Activity
Fox, P. T., Raichle, M. E., Mintun, M. A., & Dence, C. (1988) · Science · doi:10.1126/science.3260686 · Cited by 1,796
Cited by
Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.
Kwong, K. K., Belliveau, J. W., Chesler, D. A., Goldberg, I. E., Weisskoff, R. M., Poncelet, B. P., Kennedy, D. N., Hoppel, B. E., Cohen, M. S., & Turner, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5675 · Cited by 4,212
Pellerin, L., & Magistretti, P. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.22.10625 · Cited by 2,927
Brain energy metabolism: focus on Astrocyte-neuron metabolic cooperation
Bélanger, M., Allaman, I., & Magistretti, P. J. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.016 · Cited by 2,313
Dynamic Statistical Parametric Mapping
Dale, A. M., Liu, A. K., Fischl, B. R., Buckner, R. L., Belliveau, J. W., Lewine, J. D., & Halgren, E. (2000) · Neuron · doi:10.1016/s0896-6273(00)81138-1 · Cited by 1,787
Synaptic Energy Use and Supply
Harris, J. J., Jolivet, R., & Attwell, D. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.019 · Cited by 1,747
Metadata
- Authors
- Prichard, J., Rothman, D., Novotny, E., Petroff, O., Kuwabara, T., Avison, M., Howseman, A., Hanstock, C., & Shulman, R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-07
- Volume
- 88
- Issue
- 13
- Pages
- 5829-5831
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1978262170
- Cited by
- 614
- References
- 1
- FWCI
- 15.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Prichard, J., Rothman, D., Novotny, E., Petroff, O., Kuwabara, T., Avison, M., Howseman, A., Hanstock, C., & Shulman, R. (1991). Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.13.5829
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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