The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A conserved retina-specific gene encodes a basic motif/leucine zipper domain.
Open accessAbstract
Using subtraction cloning, we have isolated a human cDNA, AS321, which is expressed in retina and retinoblastoma cell lines but not in any other tissue or cell line tested. AS321 mRNA is detected in all cells of neural retina, with a high level of expression in photoreceptors. The polypeptide sequence deduced from the cDNA reveals consensus phosphorylation sites for protein kinase A and proline-directed protein kinase. Its C-terminal region contains a basic motif and a leucine zipper domain similar to the DNA binding proteins of the jun and fos oncoprotein family, and it shows a strong similarity to the product of an avian retroviral oncogene, v-maf. The gene for AS321 is conserved during evolution and is expressed in vertebrate retina. We propose to name the gene NRL (neural retina leucine zipper.
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Cites
Stimulus-transcription coupling in neurons: role of cellular immediate-early genes
Morgan, J. I., & Curran, T. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90096-9 · Cited by 969
Cited by
Nrl is required for rod photoreceptor development
Mears, A. J., Kondo, M., Swain, P. K., Takada, Y., Bush, R. A., Saunders, T. L., Sieving, P. A., & Swaroop, A. (2001) · Nature Genetics · doi:10.1038/ng774 · Cited by 912
Self-citationThe Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4
Ho, I.-C., Hodge, M. R., Rooney, J. W., & Glimcher, L. H. (1996) · Cell · doi:10.1016/s0092-8674(00)81299-4 · Cited by 667
Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
Swaroop, A., Kim, D., & Forrest, D. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2880 · Cited by 560
Self-citationIsolation of an AP-1 Repressor by a Novel Method for Detecting Protein-Protein Interactions
Aronheim, A., Zandi, E., Hennemann, H., Elledge, S. J., & Karin, M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.6.3094 · Cited by 462
Regulatory mechanisms of cellular response to oxidative stress
Itoh, K., Ishii, T., Wakabayashi, N., & Yamamoto, M. (1999) · Free Radical Research · doi:10.1080/10715769900300881 · Cited by 347
Metadata
- Authors
- Swaroop, A., Xu, J. Z., Pawar, H., Jackson, A., Skolnick, C., & Agarwal, N.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1992-01
- Volume
- 89
- Issue
- 1
- Pages
- 266-270
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2043372546
- Cited by
- 305
- References
- 1
- FWCI
- 3.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Swaroop, A., Xu, J. Z., Pawar, H., Jackson, A., Skolnick, C., & Agarwal, N. (1992). A conserved retina-specific gene encodes a basic motif/leucine zipper domain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.89.1.266
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