Cited by 936Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesSubstance Abuse Treatment and Outcomes

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Activation of memory circuits during cue-elicited cocaine craving.

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Grant, S, London, E D, Newlin, D B, Villemagne, V L, Liu, X, Contoreggi, C, Phillips, R L, Kimes, A S, Margolin, A·1996·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.93.21.12040PMC PMC38179

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Abstract

Evidence accumulated over more than 45 years has indicated that environmental stimuli can induce craving for drugs of abuse in individuals who have addictive disorders. However, the brain mechanisms that subserve such craving have not been elucidated. Here a positron emission tomographic study shows increased glucose metabolism in cortical and limbic regions implicated in several forms of memory when human volunteers who abuse cocaine are exposed to drug-related stimuli. Correlations of metabolic increases in the dorsolateral prefrontal cortex, medial temporal lobe (amygdala), and cerebellum with self-reports of craving suggest that a distributed neural network, which integrates emotional and cognitive aspects of memory, links environmental cues with cocaine craving.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
Profile of mood states
McNair, D. M. (1992) · Medical Entomology and Zoology · Cited by 2,527
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method
Phelps, M. E., Huang, S. C., Hoffman, E. J., Selin, C. E., Sokoloff, L., & Kuhl, D. E. (1979) · Annals of Neurology · doi:10.1002/ana.410060502 · Cited by 2,417
A CLASSIFICATION OF HAND PREFERENCE BY ASSOCIATION ANALYSIS
Annett, M. (1970) · British Journal of Psychology · doi:10.1111/j.2044-8295.1970.tb01248.x · Cited by 2,271
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function
Middleton, F. A., & Strick, P. L. (1994) · Science · doi:10.1126/science.7939688 · Cited by 1,356
β-Adrenergic activation and memory for emotional events
Cahill, L., Prins, B., Weber, M., & McGaugh, J. L. (1994) · Nature · doi:10.1038/371702a0 · Cited by 1,271
Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.
Stewart, J., de Wit, H., & Eikelboom, R. (1984) · Psychological Review · doi:10.1037/0033-295x.91.2.251 · Cited by 1,261
The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.
Reivich, M., Kuhl, D., Wolf, A. P., Greenberg, J. H., Phelps, M. E., Ido, T., Casella, V., Fowler, J. S., Hoffman, E., Alavi, A. A., et al. (1979) · Circulation Research · doi:10.1161/01.res.44.1.127 · Cited by 1,223

Show all 38 references

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Self-citation
Dopamine receptor partial agonists could address the duality of cocaine craving
Childress, A. R., & O’Brien, C. P. (2000) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01422-4 · Cited by 62
Functional imaging of craving.
Hommer, D. W. (1999) · PubMed · Cited by 61
eIF2 Dephosphorylation in Basolateral Amygdala Mediates Reconsolidation of Drug Memory
Jian, M., Luo, Y.-X., Xue, Y., Han, Y., Shi, H., Liu, J., Wu, Y., Wu, P., Meng, S., Deng, J.-H., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0934-14.2014 · Cited by 61
NEUROBIOLOGY OF TOBACCO SMOKING AND OTHER ADDICTIVE DISORDERS
Gamberino, W. C., & Gold, M. S. (1999) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70078-2 · Cited by 60
Limbic Responsiveness to Procaine in Cocaine-Addicted Subjects
Adinoff, B. H., Devous, M. D., Best, S. M., George, M. S., Alexander, D., & Payne, K. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.390 · Cited by 61
Quitting-unmotivated and quitting-motivated cigarette smokers exhibit different patterns of cue-elicited brain activation when anticipating an opportunity to smoke.
Wilson, S. J., Sayette, M. A., & Fiez, J. A. (2011) · Journal of Abnormal Psychology · doi:10.1037/a0025112 · Cited by 62
Selective Memory for Alcohol Cues in Alcoholics and Its Relation to Craving
Franken, I. H. A., Rosso, M., & van Honk, J. (2003) · Cognitive Therapy and Research · doi:10.1023/a:1025480615623 · Cited by 60
Extinction of Cocaine Self-Administration Produces a Differential Time-Related Regulation of Proenkephalin Gene Expression in Rat Brain
Crespo, J. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00221-4 · Cited by 60
Cannabis abuse is associated with decision-making impairment among first-episode patients with schizophrenia-spectrum psychosis
Mata, I. F., Rodríguez-Sánchez, J. M., Pelayo‐Terán, J. M., Pérez‐Iglesias, R., González‐Blanch, C., Ramírez-Bonilla, M. L., Martínez‐García, O., Vázquez‐Barquero, J. L., & Crespo‐Facorro, B. (2007) · Psychological Medicine · doi:10.1017/s0033291707002218 · Cited by 60
Episodic Memories and Their Relevance for Psychoactive Drug Use and Addiction
Müller, C. P. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00034 · Cited by 62
Dopaminergic mechanisms of reinstatement of MDMA‐seeking behaviour in rats
Schenk, S., Gittings, D., & Colussi‐Mas, J. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.01193.x · Cited by 59
Methylphenidate Attenuates Limbic Brain Inhibition after Cocaine-Cues Exposure in Cocaine Abusers
Volkow, N. D., Wang, G., Tomasi, D. G., Telang, F., Fowler, J. S., Pradhan, K., Jayne, M. C., Logan, J., Goldstein, R. Z., Alia‐Klein, N., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011509 · Cited by 60
Extracellular signal‐regulated kinases (ERKs) modulate cocaine‐induced gene expression in the mouse amygdala
Radwańska, K., Caboche, J., & Kaczmarek, L. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04286.x · Cited by 60
The cerebellum on cocaine: plasticity and metaplasticity
Vazquez-Sanroman, D. B., Leto, K., Cerezo, M., Carbo‐Gas, M., Sanchis‐Segura, C., Carulli, D., Rossi, F., & Miquel, M. (2015) · Addiction Biology · doi:10.1111/adb.12223 · Cited by 59
Targeting Endogenous Mu- and Delta-Opioid Receptor Systems for the Treatment of Drug Addiction
Shippenberg, T. S., LeFevour, A., & Chefer, V. I. (2008) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152708786927813 · Cited by 58
Involvement of the Nucleus Accumbens and Medial Prefrontal Cortex in the Expression of Conditioned Hyperactivity to a Cocaine-Associated Environment in Rats
Franklin, T. R. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00162-7 · Cited by 58
Cocaine cue-induced dopamine release in the human prefrontal cortex
Milella, M. S., Fotros, A., Gravel, P., Casey, K. F., Larcher, K., Verhaeghe, J. A. J., Cox, S. M. L., Reader, A. J., Dagher, A., Benkelfat, C., et al. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.150207 · Cited by 56

Authors: Grant, S., London, E. D., Newlin, D. B., Villemagne, V. L., Liu, X., Contoreggi, C., Phillips, R. L., Kimes, A. S., & Margolin, A.
Affiliations: National Institute on Drug Abuse (US)
ORCID: London, E D
Villemagne, V L
Phillips, R L
Kimes, A S
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1996-10-15
Volume: 93
Issue: 21
Pages: 12040-12045
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.93.21.12040
PMC: PMC38179
OpenAlex: W2022235619
Cited by: 936
References: 38
Citations by year: 2026: 4 · 2025: 5 · 2024: 16 · 2023: 18 · 2022: 9 · 2021: 18 · 2020: 17 · 2019: 19 · 2018: 27 · 2017: 30 · 2016: 28 · 2015: 35 · 2014: 30 · 2013: 54 · 2012: 27
FWCI: 6.48
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords: cocaine craving, drug-related cues, memory circuits, cocaine dependence, glucose metabolism, dorsolateral prefrontal cortex, amygdala, medial temporal lobe, cerebellum, emotional memory, cognitive memory, cue reactivity, artificial neural networks
MeSH terms: Adult, Analysis of Variance, Brain, Cocaine, Deoxyglucose, Female, Fluorine Radioisotopes, Glucose, Humans, Functional Laterality, Male, Memory, Opioid-Related Disorders, Tomography, Emission-Computed, Fluorodeoxyglucose F18, Substance-Related Disorders

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Activation of memory circuits during cue-elicited cocaine craving.

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