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Activation of memory circuits during cue-elicited cocaine craving.

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Grant, S, London, E D, Newlin, D B, Villemagne, V L, Liu, X, Contoreggi, C, Phillips, R L, Kimes, A S, Margolin, A·1996·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.93.21.12040PMC PMC38179

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Abstract

Evidence accumulated over more than 45 years has indicated that environmental stimuli can induce craving for drugs of abuse in individuals who have addictive disorders. However, the brain mechanisms that subserve such craving have not been elucidated. Here a positron emission tomographic study shows increased glucose metabolism in cortical and limbic regions implicated in several forms of memory when human volunteers who abuse cocaine are exposed to drug-related stimuli. Correlations of metabolic increases in the dorsolateral prefrontal cortex, medial temporal lobe (amygdala), and cerebellum with self-reports of craving suggest that a distributed neural network, which integrates emotional and cognitive aspects of memory, links environmental cues with cocaine craving.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
Profile of mood states
McNair, D. M. (1992) · Medical Entomology and Zoology · Cited by 2,527
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method
Phelps, M. E., Huang, S. C., Hoffman, E. J., Selin, C. E., Sokoloff, L., & Kuhl, D. E. (1979) · Annals of Neurology · doi:10.1002/ana.410060502 · Cited by 2,417
A CLASSIFICATION OF HAND PREFERENCE BY ASSOCIATION ANALYSIS
Annett, M. (1970) · British Journal of Psychology · doi:10.1111/j.2044-8295.1970.tb01248.x · Cited by 2,271
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function
Middleton, F. A., & Strick, P. L. (1994) · Science · doi:10.1126/science.7939688 · Cited by 1,356
β-Adrenergic activation and memory for emotional events
Cahill, L., Prins, B., Weber, M., & McGaugh, J. L. (1994) · Nature · doi:10.1038/371702a0 · Cited by 1,271
Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.
Stewart, J., de Wit, H., & Eikelboom, R. (1984) · Psychological Review · doi:10.1037/0033-295x.91.2.251 · Cited by 1,261
The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.
Reivich, M., Kuhl, D., Wolf, A. P., Greenberg, J. H., Phelps, M. E., Ido, T., Casella, V., Fowler, J. S., Hoffman, E., Alavi, A. A., et al. (1979) · Circulation Research · doi:10.1161/01.res.44.1.127 · Cited by 1,223

Show all 38 references

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Neurocircuitry of Addiction
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667
Chronic stress, drug use, and vulnerability to addiction
Sinha, R. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1441.030 · Cited by 1,904
Addiction Is a Brain Disease, and It Matters
Leshner, A. I. (1997) · Science · doi:10.1126/science.278.5335.45 · Cited by 1,615
Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli
Jentsch, J. D., & Taylor, J. R. (1999) · Psychopharmacology · doi:10.1007/pl00005483 · Cited by 1,545
Limbic Activation During Cue-Induced Cocaine Craving
Childress, A. R., Mozley, P. D., McElgin, W., Fitzgerald, J., Reivich, M., & O’Brien, C. P. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.1.11 · Cited by 1,513
How does stress increase risk of drug abuse and relapse?
Sinha, R. (2001) · Psychopharmacology · doi:10.1007/s002130100917 · Cited by 1,505
Addiction and the brain: The neurobiology of compulsion and its persistence
Hyman, S. E., & Malenka, R. C. (2001) · Nature reviews. Neuroscience · doi:10.1038/35094560 · Cited by 1,337
Drug addiction: updating actions to habits to compulsions ten years on
Everitt, B. J., & Robbins, T. W. (2016) · Annual Review of Psychology · doi:10.1146/annurev-psych-122414-033457 · Cited by 1,225
Acute effects of cocaine on human brain activity and emotion
Breiter, H. C., Gollub, R. L., Weisskoff, R. M., Kennedy, D. N., Makris, N., Berke, J. D., Goodman, J. M., Kantor, H. L., Gastfriend, D. R., Riorden, J. P., et al. (1997) · Neuron · doi:10.1016/s0896-6273(00)80374-8 · Cited by 1,270
Damage to the insula disrupts addiction to cigarette smoking
Naqvi, N. H., Rudrauf, D., Damasio, H., & Bechara, A. (2007) · Science · doi:10.1126/science.1135926 · Cited by 1,245
Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex
Volkow, N. D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.318 · Cited by 1,240
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
Pierce, R. C., & Kalivas, P. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00021-0 · Cited by 1,239
Dopamine in drug abuse and addiction: results from imaging studies and treatment implications
Volkow, N. D., Fowler, J. S., Wang, G.-J., & Swanson, J. M. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001507 · Cited by 1,101
The human amygdala and the emotional evaluation of sensory stimuli
Zald, D. H. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00248-5 · Cited by 1,062
Cognitive neuroscience of self-regulation failure
Heatherton, T. F., & Wagner, D. D. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.12.005 · Cited by 1,033
The psychology and neurobiology of addiction: an incentive–sensitization view
Robinson, T. E., & Berridge, K. C. (2000) · Addiction · doi:10.1046/j.1360-0443.95.8s2.19.x · Cited by 1,507
Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
Everitt, B. J., Belin, D., Economidou, D., Pelloux, Y., Dalley, J. W., & Robbins, T. W. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0089 · Cited by 974
The Amygdala: a functional analysis
Aggleton, J. P. (2000) · Cited by 966
Imaginary Relish and Exquisite Torture: The Elaborated Intrusion Theory of Desire.
Kavanagh, D. J., Andrade, J., & May, J. (2005) · Psychological Review · doi:10.1037/0033-295x.112.2.446 · Cited by 956
Addiction: Beyond dopamine reward circuitry
Volkow, N. D., Wang, G.-J., Fowler, J. S., Tomasi, D., & Telang, F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010654108 · Cited by 959
Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli
Garavan, H., Pankiewicz, J., Bloom, A., Cho, J.-K., Sperry, L., Ross, T. J., Salmeron, B. J., Risinger, R., Kelley, D., & Stein, E. A. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.11.1789 · Cited by 931
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior
McFarland, K., & Kalivas, P. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-21-08655.2001 · Cited by 905
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Volkow, N. D., Chang, L., Wang, G.-J., Fowler, J. S., Ding, Y.-S., Sedler, M., Logan, J., Franceschi, D., Gatley, J., Hitzemann, R., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.12.2015 · Cited by 916
The addicted human brain: insights from imaging studies
Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18533 · Cited by 916
Prefrontal Glutamate Release into the Core of the Nucleus Accumbens Mediates Cocaine-Induced Reinstatement of Drug-Seeking Behavior
McFarland, K., Lapish, C. C., & Kalivas, P. W. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03531.2003 · Cited by 884
Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences.
Bechara, A., & Damasio, H. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(02)00015-5 · Cited by 889
The neuropsychological basis of addictive behaviour
Everitt, B. J., Dickinson, A., & Robbins, T. W. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00088-1 · Cited by 808
Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology
Volkow, N. D., Wang, G.-J., Fowler, J. S., & Telang, F. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0107 · Cited by 809
Obesity and addiction: Neurobiological overlaps
Volkow, N. D., Wang, G. ‐., Tomasi, D., & Baler, R. D. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01031.x · Cited by 800
Cerebellar networks with the cerebral cortex and basal ganglia
Bostan, A. C., Dum, R. P., & Strick, P. L. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.03.003 · Cited by 759
Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches
Franken, I. H. A. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(03)00081-2 · Cited by 805
Extinction circuits for fear and addiction overlap in prefrontal cortex
Peters, J., Kalivas, P. W., & Quirk, G. J. (2009) · Learning & Memory · doi:10.1101/lm.1041309 · Cited by 736
Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum
Belin, D., & Everitt, B. J. (2008) · Neuron · doi:10.1016/j.neuron.2007.12.019 · Cited by 697
Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria
Drevets, W. C., Gautier, C., Price, J. C., Kupfer, D. J., Kinahan, P. E., Grace, A. A., Price, J. L., & Mathis, C. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01038-6 · Cited by 706
Neural correlates of food addiction
Gearhardt, A. N. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.32 · Cited by 707
Psychomotor stimulant addiction: a neural systems perspective
Everitt, B. J., & Wolf, M. E. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03312.2002 · Cited by 700
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Everitt, B. J., & Robbins, T. W. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.010 · Cited by 675
Conditioning factors in drug abuse: can they explain compulsion?
O’Brien, C. P., Childress, A. R., Ehrman, R. N., & Robbins, S. J. (1998) · Journal of Psychopharmacology · doi:10.1177/026988119801200103 · Cited by 687
Images of desire: food-craving activation during fMRI
Pelchat, M. L., Johnson, A., Chan, R., Valdez, J., & Ragland, J. D. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.023 · Cited by 667
Executive dysfunction in cocaine addiction: evidence for discordant frontal, cingulate, and cerebellar activity
Hester, R., & Garavan, H. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3321-04.2004 · Cited by 657
Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior
Steketee, J. D., & Kalivas, P. W. (2011) · Pharmacological Reviews · doi:10.1124/pr.109.001933 · Cited by 671
Drug abusers show impaired performance in a laboratory test of decision making
Grant, S. (2000) · Neuropsychologia · doi:10.1016/s0028-3932(99)00158-x · Cited by 625
Self-citation
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure
Epstein, D. H., Preston, K. L., Stewart, J., & Shaham, Y. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0529-6 · Cited by 627
The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies
Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.07.019 · Cited by 616
Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics
Gr�sser, S. M., Wrase, J., Klein, S., Hermann, D., Smolka, M. N., Ruf, M., Weber-Fahr, W., Flor, H., Mann, K., Braus, D. F., et al. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1828-4 · Cited by 598
Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients
Franklin, T. R., Acton, P. D., Maldjian, J. A., Gray, J. D., Croft, J. R., Dackis, C. A., O’Brien, C. P., & Childress, A. R. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01269-0 · Cited by 599
Intertemporal choice – toward an integrative framework
Berns, G. S., Laibson, D., & Loewenstein, G. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.08.011 · Cited by 580
Brain circuitry and the reinstatement of cocaine-seeking behavior
Kalivas, P., & McFarland, K. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1393-2 · Cited by 613
Addiction circuitry in the human brain
Volkow, N. D., Wang, G.-J., Fowler, J. S., & Tomasi, D. (2012) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010611-134625 · Cited by 592
Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task
Bolla, K. I., Eldreth, D. A., London, E. D., Kiehl, K. A., Mouratidis, M., Contoreggi, C. S., Matochik, J. A., Kurian, V., Cadet, J. L., Kimes, A. S., et al. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00113-7 · Cited by 578
Self-citation
Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward?
Bechara, A., Dolan, S., & Hindes, A. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(02)00016-7 · Cited by 580
Prefrontal Control and Internet Addiction: A Theoretical Model and Review of Neuropsychological and Neuroimaging Findings
Brand, M., Young, K. S., & Laier, C. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00375 · Cited by 565
“…to the Internet-related stimuli so strong that they experience cue-reactivity and craving, as it is well-known from substance dependency (e.g., Grant et al., 1996; Anton, 1999; Childress et al., 1999; Tiffany and Conklin, 2000; Bonson et al., 2002; Brody et al., 2002, 2007; Franken, 2003; Dom…”
Background
Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist
Pilla, M. A., Perachon, S., Sautel, F., Garrido, F., Mann, A., Wermuth, C. G., Schwartz, J.-C., Everitt, B. J., & Sokoloff, P. (1999) · Nature · doi:10.1038/22560 · Cited by 565
The clinical significance of drug craving
Tiffany, S. T., & Wray, J. M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06298.x · Cited by 556
Neurobiology of Decision Making: A Selective Review from a Neurocognitive and Clinical Perspective
Ernst, M., & Paulus, M. P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.06.004 · Cited by 469
Neurobiologic processes in drug reward and addiction
Adinoff, B. (2004) · Harvard Review of Psychiatry · doi:10.1080/10673220490910844 · Cited by 546
Abnormal Brain Structure Implicated in Stimulant Drug Addiction
Ersche, K. D., Jones, P. S., Williams, G. B., Turton, A. J., Robbins, T. W., & Bullmore, E. T. (2012) · Science · doi:10.1126/science.1214463 · Cited by 546
Glutamate Transmission in the Nucleus Accumbens Mediates Relapse in Cocaine Addiction
Cornish, J. L., & Kalivas, P. W. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-15-j0006.2000 · Cited by 553
Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies
Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.10.013 · Cited by 513
Differential Brain Activity in Alcoholics and Social Drinkers to Alcohol Cues: Relationship to Craving
Myrick, H., Anton, R. F., Li, X., Henderson, S., Drobes, D., Voronin, K., & George, M. S. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300295 · Cited by 521
Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction
Volkow, N. D., Wang, G. J., Fowler, J. S., Tomasi, D., & Baler, R. (2011) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2011_169 · Cited by 525
Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies
Volkow, N. (2002) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2002.4099 · Cited by 514
Neural systems and cue-induced cocaine craving
Bonson, K. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00371-2 · Cited by 507
The nucleus accumbens: a comprehensive review
Salgado, S., & Kaplitt, M. G. (2015) · Stereotactic and Functional Neurosurgery · doi:10.1159/000368279 · Cited by 489
Differential control over cocaine-seeking behavior by nucleus accumbens core and shell
Ito, R., Robbins, T. W., & Everitt, B. J. (2004) · Nature Neuroscience · doi:10.1038/nn1217 · Cited by 501
A unified framework for addiction: Vulnerabilities in the decision process
Redish, A. D., Jensen, S., & Johnson, A. (2008) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0800472x · Cited by 501
Imaging stress‐ and cue‐induced drug and alcohol craving: association with relapse and clinical implications
SINHA, R., & LI, C. ‐. R. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036960 · Cited by 497
Relapse to cocaine-seeking after hippocampal theta burst stimulation
Vorel, S. R., Liu, X., Hayes, R. J., Spector, J. A., & Gardner, E. L. (2001) · Science · doi:10.1126/science.1058043 · Cited by 486
Self-citation
Pharmacology and behavioral pharmacology of the mesocortical dopamine system
Tzschentke, T. M. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00033-2 · Cited by 481
Infralimbic Prefrontal Cortex Is Responsible for Inhibiting Cocaine Seeking in Extinguished Rats
Peters, J., LaLumiere, R. T., & Kalivas, P. W. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1045-08.2008 · Cited by 537
Amphetamine-induced increases in extracellular dopamine, drug wanting, and novelty seeking: a PET/[11C] raclopride study in healthy men
Leyton, M. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00366-4 · Cited by 476
Drug Addiction and the Memory Systems of the Brain
Robbins, T. W., Ersche, K. D., & Everitt, B. J. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1441.020 · Cited by 467
Central amygdala ERK signaling pathway is critical to incubation of cocaine craving
Lü, L., Hope, B. T., Dempsey, J., Liu, S. Y., Bossert, J. M., & Shaham, Y. (2005) · Nature Neuroscience · doi:10.1038/nn1383 · Cited by 452
Fos Protein Expression and Cocaine-Seeking Behavior in Rats after Exposure to a Cocaine Self-Administration Environment
Neisewander, J. L., Baker, D. L., Fuchs, R. A., Tran-Nguyen, L. T. L., Palmer, A., & Marshall, J. F. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00798.2000 · Cited by 432
Functional Magnetic Resonance Imaging of Human Brain Activation During Cue-Induced Cocaine Craving
Maas, L. C., Lukas, S. E., Kaufman, M. J., Weiss, R. D., Daniels, S. L., Rogers, V. W., Kukes, T. J., & Renshaw, P. F. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.1.124 · Cited by 434
The role of stress in addiction relapse
Sinha, R. (2007) · Current Psychiatry Reports · doi:10.1007/s11920-007-0050-6 · Cited by 423
Activation in Mesolimbic and Visuospatial Neural Circuits Elicited by Smoking Cues: Evidence From Functional Magnetic Resonance Imaging
Due, D. L., Huettel, S. A., HALL, W. G., & Rubin, D. C. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.6.954 · Cited by 437
Brain metabolic changes during cigarette craving
Brody, A. L., Mandelkern, M. A., London, E. D., Childress, A. R., Lee, G. S., Bota, R. G., Ho, M. L., Saxena, S., Baxter, L. R., Madsen, D., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.12.1162 · Cited by 425
Self-citation
Functional Magnetic Resonance Imaging of Cocaine Craving
Wexler, B. E., Gottschalk, C. H., Fulbright, R. K., Prohovnik, I., Lacadie, C. M., Rounsaville, B. J., & Gore, J. C. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.1.86 · Cited by 420
The neurocircuitry of addiction: an overview
Feltenstein, M. W., & See, R. E. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.51 · Cited by 421
Control of cocaine-seeking behavior by drug-associated stimuli in rats: Effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens
Weiss, F., Maldonado-Vlaar, C. S., Parsons, L. H., Kerr, T. M., Smith, D. L., & Ben‐Shahar, O. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4321 · Cited by 416
New findings on biological factors predicting addiction relapse vulnerability
Sinha, R. (2011) · Current Psychiatry Reports · doi:10.1007/s11920-011-0224-0 · Cited by 401
Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction
Volkow, N. D., Wang, G.-J., Fowler, J. S., Hitzemann, R., Angrist, B., Gatley, S. J., Logan, J., Ding, Y.-S., & Pappas, N. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.1.19 · Cited by 405
Prefrontal responses to drug cues: a neurocognitive analysis
Wilson, S. J., Sayette, M. A., & Fiez, J. A. (2004) · Nature Neuroscience · doi:10.1038/nn1200 · Cited by 408
Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies
Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200209000-00008 · Cited by 398
Exposure to appetitive food stimuli markedly activates the human brain
Wang, G.-J., Volkow, N. D., Telang, F., Jayne, M., Ma, J., Rao, M., Zhu, W., Wong, C. T., Pappas, N. R., Geliebter, A., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.026 · Cited by 402
Selective inactivation of the dorsomedial prefrontal cortex and the basolateral amygdala attenuates conditioned-cued reinstatement of extinguished cocaine-seeking behavior in rats
McLaughlin, J., & See, R. E. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1196-x · Cited by 402
Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction
Aston‐Jones, G., Smith, R. J., Sartor, G. C., Moorman, D. E., Massi, L., Tahsili‐Fahadan, P., & Richardson, K. A. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.106 · Cited by 399
Neural substrates of faulty decision-making in abstinent marijuana users
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Authors: Grant, S., London, E. D., Newlin, D. B., Villemagne, V. L., Liu, X., Contoreggi, C., Phillips, R. L., Kimes, A. S., & Margolin, A.
Affiliations: National Institute on Drug Abuse (US)
ORCID: London, E D
Villemagne, V L
Phillips, R L
Kimes, A S
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1996-10-15
Volume: 93
Issue: 21
Pages: 12040-12045
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.93.21.12040
PMC: PMC38179
OpenAlex: W2022235619
Cited by: 936
References: 38
Citations by year: 2026: 4 · 2025: 5 · 2024: 16 · 2023: 18 · 2022: 9 · 2021: 18 · 2020: 17 · 2019: 19 · 2018: 27 · 2017: 30 · 2016: 28 · 2015: 35 · 2014: 30 · 2013: 54 · 2012: 27
FWCI: 6.48
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords: cocaine craving, drug-related cues, memory circuits, cocaine dependence, glucose metabolism, dorsolateral prefrontal cortex, amygdala, medial temporal lobe, cerebellum, emotional memory, cognitive memory, cue reactivity, artificial neural networks
MeSH terms: Adult, Analysis of Variance, Brain, Cocaine, Deoxyglucose, Female, Fluorine Radioisotopes, Glucose, Humans, Functional Laterality, Male, Memory, Opioid-Related Disorders, Tomography, Emission-Computed, Fluorodeoxyglucose F18, Substance-Related Disorders

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Activation of memory circuits during cue-elicited cocaine craving.

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