The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Vascular endothelial growth factor B, a novel growth factor for endothelial cells.
Open accessAbstract
We have isolated and characterized a novel growth factor for endothelial cells, vascular endothelial growth factor B (VEGF-B), with structural similarities to vascular endothelial growth factor (VEGF) and placenta growth factor. VEGF-B was particularly abundant in heart and skeletal muscle and was coexpressed with VEGF in these and other tissues. VEGF-B formed cell-surface-associated disulfide-linked homodimers and heterodimerized with VEGF when coexpressed. Conditioned medium from transfected 293EBNA cells expressing VEGF-B stimulated DNA synthesis in endothelial cells. Our results suggest that VEGF-B has a role in angiogenesis and endothelial cell growth, particularly in muscle.
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Cites
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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
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Cited by
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
Hanahan, D., & Folkman, J. (1996) · Cell · doi:10.1016/s0092-8674(00)80108-7 · Cited by 6,885
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
Ferrara, N., Hillan, K. J., Gerber, H.-P., & Novotny, W. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1381 · Cited by 2,625
Vascular Endothelial Growth Factor and Angiogenesis
Hoeben, A., Landuyt, B., Highley, M. S., Wildiers, H., Van Oosterom, A. T., & De Bruijn, E. A. (2004) · Pharmacological Reviews · doi:10.1124/pr.56.4.3 · Cited by 1,824
VEGF and the quest for tumour angiogenesis factors
Ferrara, N. (2002) · Nature Reviews Cancer · doi:10.1038/nrc909 · Cited by 1,536
Role of tumor microenvironment in tumorigenesis
Wang, M., Zhao, J., Zhang, L., Wei, F., Lian, Y., Wu, Y., Gong, Z., Zhang, S., Zhou, J., Cao, K., et al. (2017) · Journal of Cancer · doi:10.7150/jca.17648 · Cited by 1,404
Metadata
- Authors
- Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V, Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K., & Eriksson, U.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1996-03-19
- Volume
- 93
- Issue
- 6
- Pages
- 2576-2581
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2034393061
- Cited by
- 803
- References
- 34
- FWCI
- 19.67
- Type
- journal article
- Language
- en
- Open access
- green
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- Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V, Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K., & Eriksson, U. (1996). Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.93.6.2576
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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