The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
The three yeast A kinases have specific signaling functions in pseudohyphal growth
Open accessAbstract
The three yeast A kinase catalytic subunit isoforms are redundant for viability. We demonstrate that they have dramatically different roles in pseudohyphal development: Tpk2 is essential, whereas Tpk3 inhibits. Tpk1 has no discernible effect. Two-hybrid analysis identified the transcription factor Sfl1 as a protein that interacts specifically with Tpk2, but not Tpk1 or Tpk3. Deletion of SFL1 enhances pseudohyphal and invasive growth. Flo11, a cell surface flocculin required for pseudohyphal development, is transcriptionally regulated by Tpk2 and Sfl1. Genetic evidence indicates that Tpk2 acts upstream of Sfl1 in the regulation of Flo11.
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Cites
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Cited by
Signal Transduction Cascades Regulating Fungal Development and Virulence
Lengeler, K. B., Davidson, R. C., D'souza, C., Harashima, T., Shen, W.-C., Wang, P., Pan, X., Waugh, M., & Heitman, J. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.4.746-785.2000 · Cited by 915
Roberts, C. J., Nelson, B., Marton, M. J., Stoughton, R., Meyer, M. R., Bennett, H. A., He, Y. D., Dai, H., Walker, W. L., Hughes, T. R., et al. (2000) · Science · doi:10.1126/science.287.5454.873 · Cited by 855
Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression
Marion, R. M., Regev, A., Segal, E., Barash, Y., Koller, D., Friedman, N., & O'Shea, E. K. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405353101 · Cited by 386
Pan, X., & Heitman, J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4874 · Cited by 349
Yeast flocculation: what brewers should know
Verstrepen, K. J., Derdelinckx, G., Verachtert, H., & Delvaux, F. R. (2003) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-002-1200-8 · Cited by 345
Metadata
- Authors
- Robertson, L. S., & Fink, G. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1998-11-10
- Volume
- 95
- Issue
- 23
- Pages
- 13783-13787
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2043296955
- Cited by
- 326
- References
- 24
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Robertson, L. S., & Fink, G. R. (1998). The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.95.23.13783
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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