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Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice LackingN-Deacetylase/N-Sulfotransferase-1
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Ndst1-/- embryos exhibit altered liver HS structure.
“Systemic inactivation of Ndst1 in mice causes perinatal lethality due to brain and lung defects (41)(42)(43), and Ndst1 -/-embryos exhibit altered liver HS structure (41,44).”
From Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members (2007) · cites this paper as [41]
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Metadata
- Authors
- Ringvall, M., Ledin, J., Holmborn, K., van Kuppevelt, T., Ellin, F., Eriksson, I., Olofsson, A.-M., Kjellén, L., & Forsberg, E.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 275
- Issue
- 34
- Pages
- 25926-25930
- ISSN
- 0021-9258
- Cited by
- 217
- References
- 0
- Language
- en
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