Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Mitochondria as the central control point of apoptosis

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The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

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Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

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A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

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The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast

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A Human Dynamin-related Protein Controls the Distribution of Mitochondria

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Mitochondrial Fusion in Human Cells Is Efficient, Requires the Inner Membrane Potential, and Is Mediated by Mitofusins

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The human dynamin‐related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter‐membrane space

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Photobiomodulation therapy with light-emitting diode in stimulating adipose tissue mitochondria

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Identification of genes involved in glaucoma pathogenesis using combined network analysis and empirical studies

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The Effects of Regulatory Lipids on Intracellular Membrane Fusion Mediated by Dynamin-Like GTPases

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Optic Atrophy Type 1

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Mitochondrial Dynamics: Shaping Metabolic Adaptation

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Effects of biphasic and monophasic electrical stimulation on mitochondrial dynamics, cell apoptosis, and cell proliferation

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Mgm1 is required for maintenance of mitochondrial function and virulence in Candida albicans

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Investigating the role of Sirtuins in cell reprogramming

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Automated analysis of the retinal vascular tree - parameterised data from healthy eyes

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Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways

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Mitochondrial Dysfunction in Dopaminergic Neurons Derived from Patients with LRRK2- and SNCA-Associated Genetic Forms of Parkinson’s Disease

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OPA 1 mutation affects autophagy and triggers senescence in autosomal dominant optic atrophy plus fibroblasts

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Brain Mitochondria as a Therapeutic Target for Carnosic Acid

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Cell life-or-death events in osteoporosis: All roads lead to mitochondrial dynamics

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Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

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Disruption of mitochondrial homeostasis and permeability transition pore opening in OPA1 iPSC-derived retinal ganglion cells

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Mitochondrial aberrations and ophthalmic diseases

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Mitochondrial Biology and the Identification of Biomarkers of Huntington’s Disease

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Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy

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Advances in the mechanism and treatment of mitochondrial quality control involved in myocardial infarction

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Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy

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Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells

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The use of induced pluripotent stem cells for studying and treating optic neuropathies

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A Common Missense Variant in OMA1 Associated with the Prognosis of Heart Failure

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Axonal transport dysfunction of mitochondria in traumatic brain injury: A novel therapeutic target

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The cap-translation inhibitor 4EGI-1 induces mitochondrial dysfunction via regulation of mitochondrial dynamic proteins in human glioma U251 cells

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The OPA1 Gene Mutations Are Frequent in Han Chinese Patients with Suspected Optic Neuropathy

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Mitochondria from the Outside in: The Relationship Between Inter-Organelle Crosstalk and Mitochondrial Internal Organization

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Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB

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Novel likely pathogenic variants in TMEM126A identified in non-syndromic autosomal recessive optic atrophy: two case reports

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Mitochondrial Nascent Chain Quality Control Determines Organelle Form and Function

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Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease

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Proteomic analysis reveals rattlesnake venom modulation of proteins associated with cardiac tissue damage in mouse hearts

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LIX1-mediated changes in mitochondrial metabolism control the fate of digestive mesenchyme-derived cells

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Design, synthesis and apoptosis-related antiproliferative activities of chelidonine derivatives

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Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections

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Detection of mitochondrial fission with orientation‐dependent optical Fourier filters

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Transmembrane segments of the dynamin Msp1p uncouple its functions in the control of mitochondrial morphology and genome maintenance

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Mechanisms of mitophagy: putting the powerhouse into the doghouse

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Dominant Optic Atrophy Caused by a Novel OPA1 Splice Site Mutation (IVS20+1G→A) Associated with Intron Retention

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Kechuan Decoction mitigates apoptosis of airway epithelial cells by improving lipid metabolism disorders and mitochondria dysfunction in HDM-induced asthma

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The Role of Endoplasmic Reticulum and Mitochondria in Maintaining Redox Status and Glycolytic Metabolism in Pluripotent Stem Cells

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Sericin-mediated improvement of dysmorphic cardiac mitochondria from hypercholesterolaemia is associated with maintaining mitochondrial dynamics, energy production, and mitochondrial structure

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Drp1-mediated mitochondrial fission promotes carbon tetrachloride-induced hepatic fibrogenesis in mice

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Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats

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Extramitochondrial OPA1 and adrenocortical function

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Identification of two novel OPA1 mutations in Chinese families with autosomal dominant optic atrophy.

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Genotype-phenotype and OCT correlations in Autosomal Dominant Optic Atrophy related to OPA1 gene mutations: Report of 13 Italian families

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Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress

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Inherited Optic Neuropathies

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Targeting Mitochondrial Quality Control for the Treatment of Triple-Negative Breast Cancer: From Molecular Mechanisms to Precision Therapy

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Effect of Mitochondrial and Cytosolic FXN Isoform Expression on Mitochondrial Dynamics and Metabolism

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A review for the correlation between optic atrophy 1-dependent mitochondrial fusion and cardiovascular disorders

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Trophoblast Syncytialization: A Metabolic Crossroads

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Mitochondrial Disorders Due to Nuclear OXPHOS Gene Defects

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Remodeling of Mitochondria in Apoptosis

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Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy

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A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue

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A novel OPA1 mutation causing variable age of onset autosomal dominant optic atrophy plus in an Australian family

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Impact of Mitochondrial Dynamics on Organismic Aging

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A review of disorders of cardiolipin metabolism: Pathophysiology, clinical presentation and future directions

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Disrupted Renal Mitochondrial Homeostasis after Liver Transplantation in Rats

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The Genetics of Ethambutol-Induced Optic Neuropathy: A Narrative Review

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Genetically Engineered Triple MAPT-Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics

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Empowering mitochondrial metabolism: Exploring L-lactate supplementation as a promising therapeutic approach for metabolic syndrome

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The human OPA1delTTAG mutation induces adult onset and progressive auditory neuropathy in mice

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A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family

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Metabolism and Biological Function of Cardiolipin

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Toll-like receptor 4 mediates vascular remodeling in hyperhomocysteinemia

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Advances in our Understanding of Neurodegeneration

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Aminoacidopathies and Organic Acidopathies, Mitochondrial Enzyme Defects, and Other Metabolic Errors

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Deregulated Expression of Mitochondrial Proteins Mfn2 and Bcnl3L in Placentae from Sheep Somatic Cell Nuclear Transfer (SCNT) Conceptuses

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Mitochondrial Dynamics and Apoptosis

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Polymorphism, Heteroplasmy, Mitochondrial Fusion and Diabetes

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Aberrant mitochondrial dynamics contributes to diaphragmatic weakness induced by mechanical ventilation

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Docosahexaenoic acid alleviates LPS-induced cytotoxicity in HL-1 cardiac cells via improving stress-induced mitochondrial fragmentation

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ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic

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OPA1 Mediated Fatty Acid β‐Oxidation in Hepatocyte: The Novel Insight for Melatonin Attenuated Apoptosis in Concanavalin A Induced Acute Liver Injury

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Mitochondrial homeostasis in stem cell senescence

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Mitochondrial Fission and Fusion

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Characterization of two novel intronic OPA1 mutations resulting in aberrant pre-mRNA splicing

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Diversity of Balbiani body formation in internally and externally fertilizing representatives of Osteoglossiformes ( Teleostei: Osteoglossomorpha )

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Mutations at a split codon in the GTPase-encoding domain of OPA1 cause dominant optic atrophy through different molecular mechanisms

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Multiple Cases of Auditory Neuropathy Illuminate the Importance of Subcortical Neural Synchrony for Speech-in-noise Recognition and the Frequency-following Response

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Mitochondrial Distribution and Osteocyte Mechanosensitivity

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Reduced OPA1, Mitochondrial Fragmentation and Increased Susceptibility to Apoptosis in Granular Corneal Dystrophy Type 2 Corneal Fibroblasts

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Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity

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Short-form OPA1 is a molecular chaperone in mitochondrial intermembrane space

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Mitochondrial Proteins Unveil the Mechanism by Which Physical Exercise Ameliorates Memory, Learning and Motor Activity in Hypoxic Ischemic Encephalopathy Rat Model

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The status and trends of mitochondrial dynamics research: A global bibliometric and visualized analysis

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In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts

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Two novel compound heterozygous mutations in OPA3 in two siblings with OPA3-related 3-methylglutaconic aciduria

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OPA1 mutations in Japanese patients suspected to have autosomal dominant optic atrophy

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Neuromuscular Manifestations in Mitochondrial Diseases in Children

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Micelle-assisted combination therapies for effective glioblastoma treatment

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Basic Molecular Biology of Mitochondrial Replication

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OPA 1 and Its Clinical Implications

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OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

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OPA1-dependent cristae remodeling disassembles respiratory chain supercomplexes, triggering apoptotic mitochondrial dysfunction

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Identification and functional characterization of components of the OPA1 complexes targeted during apoptotic cristae remodeling

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Release of OPA1 during Apoptosis Participates in the Rapid and Complete Release of Cytochrome c and Subsequent Mitochondrial Fragmentation

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