The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
An IAP-IAP Complex Inhibits Apoptosis
Open accessAbstract
Regulators of apoptosis are thought to work in concert, but the molecular interactions of this process are not understood. Here, we show that in response to cell death stimulation, survivin, a member of the inhibitor of apoptosis (IAP) gene family, associates with another IAP protein, XIAP, via conserved baculovirus IAP repeats. Formation of a survivin-XIAP complex promotes increased XIAP stability against ubiquitination/proteasomal destruction and synergistic inhibition of apoptosis, which is abolished in XIAP(-/-) cells. Therefore, orchestration of an IAP-IAP complex regulates apoptosis.
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Cites
1 retracted
Akt Phosphorylation and Stabilization of X-linked Inhibitor of Apoptosis Protein (XIAP)
Dan, H. C., Sun, M., Kaneko, S., Feldman, R. I., Nicosia, S. V., Wang, H.-G., Tsang, B. K., & Cheng, J. Q. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312044200 · Cited by 422
RetractedHengartner, M. O. (2000) · Nature · doi:10.1038/35037710 · Cited by 5,779
The Bcl2 family: regulators of the cellular life-or-death switch
Cory, S., & Adams, J. M. (2002) · Nature Reviews Cancer · doi:10.1038/nrc883 · Cited by 4,032
(2001) · PubMed · Cited by 2,381
Mechanisms of Caspase Activation and Inhibition during Apoptosis
Shi, Y. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00482-3 · Cited by 1,833
IAP proteins: blocking the road to death's door
Salvesen, G. S., & Duckett, C. S. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm830 · Cited by 1,756
Self-citationValidating survivin as a cancer therapeutic target
Altieri, D. C. (2003) · Nature Reviews Cancer · doi:10.1038/nrc968 · Cited by 1,206
Self-citationYang, Y., Fang, S., Jensen, J. P., Weissman, A. M., & Ashwell, J. D. (2000) · Science · doi:10.1126/science.288.5467.874 · Cited by 988
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity
Liston, P., Fong, W. G., Kelly, N. L., Toji, S., Miyazaki, T., Conte, D., Tamai, K., Craig, C. G., McBurney, M. W., & Korneluk, R. G. (2001) · Nature Cell Biology · doi:10.1038/35055027 · Cited by 441
HBXIP functions as a cofactor of survivin in apoptosis suppression
Marusawa, H. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg263 · Cited by 432
Self-citation
Cited by
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
Eckelman, B. P., Salvesen, G. S., & Scott, F. L. (2006) · The EMBO Reports · doi:10.1038/sj.embor.7400795 · Cited by 813
Self-citationThe inhibitors of apoptosis (IAPs) as cancer targets
Hunter, A. M., LaCasse, E. C., & Korneluk, R. G. (2007) · Apoptosis · doi:10.1007/s10495-007-0087-3 · Cited by 565
Apoptosis (programmed cell death) and its signals - A review
Obeng, E. (2021) · Brazilian Journal of Biology · doi:10.1590/1519-6984.228437 · Cited by 513
Srinivasula, S. M., & Ashwell, J. D. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.03.008 · Cited by 450
The Human Anti-apoptotic Proteins cIAP1 and cIAP2 Bind but Do Not Inhibit Caspases
Eckelman, B. P., & Salvesen, G. S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m510863200 · Cited by 391
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Metadata
- Authors
- Dohi, T., Okada, K., Xia, F., Wilford, C. E., Samuel, T., Welsh, K., Marusawa, H., Zou, H., Armstrong, R., Matsuzawa, S.-I., Salvesen, G. S., Reed, J. C., & Altieri, D. C.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2004-08
- Volume
- 279
- Issue
- 33
- Pages
- 34087-34090
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2151559423
- Cited by
- 398
- References
- 21
- FWCI
- 5.58
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Dohi, T., Okada, K., Xia, F., Wilford, C. E., Samuel, T., Welsh, K., Marusawa, H., Zou, H., Armstrong, R., Matsuzawa, S.-I., Salvesen, G. S., Reed, J. C., & Altieri, D. C. (2004). An IAP-IAP Complex Inhibits Apoptosis. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.c400236200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
