Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90
Bali, Purva, Pranpat, Michael, Bradner, James, Balasis, Maria, Fiskus, Warren, Guo, Fei, Rocha, Kathy, Kumaraswamy, Sandhya, Boyapalle, Sandhya, Atadja, Peter, Seto, Edward, Bhalla, Kapil·2005·Journal of Biological Chemistry
Cited by (774)
Items 401–500 of 774
- Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitorsWei‐Jan Huang, Ching‐Chow Chen, Shi-Wei Chao, Chia-Chun Yu, Chen‐Yui Yang, Jih‐Hwa Guh, Yun-Chieh Lin, Chiao-I Kuo, Ping Yang, Chung-I Chang · 2011 · European Journal of Medicinal Chemistry
- Targeted therapy in acute myeloid leukaemia: current status and future directionsCamilla Stapnes, Bjørn Tore Gjertsen, Håkon Reikvam, Øystein Bruserud · 2009 · Expert Opinion on Investigational Drugs
- The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide librariesZsófia Kutil, L. Skultetyova, David Rauh, Marat Meleshin, Ivan Šnajdr, Zora Nováková, Jana Mikesova, Jiřı́ Pavlı́ček, Martin Hadzima, Petra Baranová et al. · 2018 · The FASEB Journal
- The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent MannerJun Zhou, Chantal Chanel Vos, Ada Gjyrezi, Minoru Yoshida, Fadlo Raja Khuri, Fuyuhiko Tamanoi, Paraskevi Giannakakou · 2009 · Journal of Biological Chemistry
- An HDAC6 inhibitor reverses chemotherapy-induced mechanical hypersensitivity via an IL-10 and macrophage dependent pathwayJixiang Zhang, Jiacheng Ma, Ronnie The Phong Trinh, Cobi J. Heijnen, Annemieke Kavelaars · 2021 · Brain Behavior and Immunity
- Targeted therapies of gastrointestinal stromal tumors (GIST)—The next frontiersStefan M. Duensing, Anette U. Duensing · 2010 · Biochemical Pharmacology
- Sensitization of tumor cells by targeting histone deacetylasesPaola Perego, Valentina Zuco, Laura Gatti, Franco Zunino · 2011 · Biochemical Pharmacology
- Screening of selective histone deacetylase inhibitors by proteochemometric modelingDingfeng Wu, Qi Huang, Yida Zhang, Qingchen Zhang, Qi Liu, Jun Alex Gao, Zhiwei Cao, Ruixin Zhu · 2012 · BMC Bioinformatics
- Panobinostat for the treatment of multiple myelomaPaola E. Neri, Nizar Jacques Bahlis, Sagar Lonial · 2012 · Expert Opinion on Investigational Drugs
- Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia CellsYi Liao, Xiaojia Niu, Bailing Chen, Holly J. Edwards, Liping Xu, Chengzhi Xie, Hai Lin, Lisa Polin, Jeffrey Warren Taub, Yubin Ge et al. · 2016 · Journal of Medicinal Chemistry
- Novel Heat Shock Protein 90 Inhibitor NVP-AUY922 Synergizes With the Histone Deacetylase Inhibitor PXD101 in Induction of Death of Anaplastic Thyroid Carcinoma CellsSi Hyoung Kim, Jun Goo Kang, Chul Sik Kim, Sung‐Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Lee · 2014 · The Journal of Clinical Endocrinology & Metabolism
- HDAC Inhibitor Modulation of Proteotoxicity as a Therapeutic Approach in CancerDavid James McConkey, Matthew C. White, Wudan Yan · 2012 · Advances in cancer research
- Opportunities for histone deacetylase inhibition in amyotrophic lateral sclerosisYvonne Eileen Klingl, Donya Pakravan, Ludo Van Den Bosch · 2020 · British Journal of Pharmacology
- Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute LeukemiaNina Reßing, Julian Schliehe‐Diecks, Paris R. Watson, Melf Sönnichsen, Abigail D. Cragin, Andrea Schöler, Jing Chun Yang, Linda Schäker‐Hübner, Arndt Borkhardt, David W. Christianson et al. · 2022 · Journal of Medicinal Chemistry
- Orphan drug designation for pracinostat, volasertib and alvocidib in AMLPrithviraj Bose, Steven Grant · 2014 · Leukemia Research
- A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XLJung Jin Hwang, Yong Sook Kim, Taelim Kim, Mi Joung Kim, In Gab Jeong, Je‐Hwan Lee, Jene Choi, Se-Jin Jang, Seonggu Ro, Choung‐Soo Kim · 2011 · Investigational New Drugs
- Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cellsSilke Götze, Monique Coersmeyer, Oliver Müller, Sonja Sievers · 2014 · International Journal of Oncology
- HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2+ TumorsMikolaj Medon, Eva Vidacs, Stephin J. Vervoort, Jason Li, Misty Rayna Jenkins, Kelly M. Ramsbottom, Joseph A. Trapani, Mark John Smyth, Phillip Kevin Darcy, Peter Wisdom Atadja et al. · 2017 · Cancer Research
- HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancerTeru Hideshima, Ralph Mazitschek, Jun Qi, Naoya Mimura, Jen‐Chieh Tseng, Andrew L. Kung, James E. Bradner, Kenneth Carl Anderson · 2017 · Oncotarget
- Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cellsSangkyu Park, Jeong-A Park, Hwanmin Yoo, Han-Bum Park, Younghee Lee · 2017 · Redox Biology
- Simvastatin functions as a heat shock protein 90 inhibitor against triple‐negative breast cancerXinhui Kou, Xiaoxiao Jiang, Huijuan Liu, Xuan Wang, Fanghui Sun, Jiami Han, Jiaxing Fan, Guize Feng, Zhaohu Lin, Lan Jiang et al. · 2018 · Cancer Science
- HDAC6—An Emerging Target Against Chronic Myeloid Leukemia?Hélène Losson, Michaël Schnekenburger, Mario A. Dicato, Marc F. Diederich · 2020 · Cancers
- The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cellsSi Hyoung Kim, Jun Goo Kang, Chul Sik Kim, Sung‐Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Lee · 2015 · Endocrine
- Clinical pharmacokinetics of panobinostat, a novel histone deacetylase (HDAC) inhibitor: review and perspectivesNuggehally R. Srinivas · 2016 · Xenobiotica
- Mc1568 Inhibits Hdac6/8 Activity and Influenza a Virus Replication in Lung Epithelial Cells: Role of Hsp90 AcetylationSimona Panella, Maria Elena Marcocci, Ignacio Celestino, Sérgio Valente, Clemens Zwergel, Domenica Donatella Li Puma, Lucia Nencioni, Antonello Mai, Anna Teresa Palamara, Giovanna Simonetti · 2016 · Future Medicinal Chemistry
- HSP90: A Rising Star on the Horizon of Anticancer TargetsLuke J. Whitesell, Chengkai Dai · 2005 · Future Oncology
- Dual Targeting Strategies on Histone Deacetylase 6 (HDAC6) and Heat Shock Protein 90 (Hsp90)Davide Bonanni, Andrea Citarella, Davide Moi, Luca Pinzi, Elisa Bergamini, Giulio Rastelli · 2021 · Current Medicinal Chemistry
- S100A2 is a BRCA1/p63 coregulated tumour suppressor gene with roles in the regulation of mutant p53 stabilityNiamh E. Buckley, Zenobia D’Costa, M Kaminska, Paul B. Mullan · 2014 · Cell Death and Disease
- Differentially expressed genes and morphological changes during lengthened immobilization in rat soleus muscleJi Won Kim, Oh Yun Kwon, Myoung Hee Kim · 2006 · Differentiation
- Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stressNing Gao, Mohamed Rahmani, Xianglin Shi, Paul Dent, Steven Grant · 2005 · Blood
- Detection of histone deacetylase inhibition by noninvasive magnetic resonance spectroscopyMadhuri Sankaranarayanapillai, William P. Tong, David S. Maxwell, Ashutosh Pal, Jihai Pang, William G. Bornmann, Juri George Gelovani, Sabrina M. Ronen · 2006 · Molecular Cancer Therapeutics
- ARDent about acetylation and deacetylation in hypoxia signallingRebecca L. Bilton, Eric Trottier, Jacques Pouysségur, M. Christiane Brahimi-Horn · 2006 · Trends in Cell Biology
- Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluationBohonowych, Jessica ES, Peng, Shuping, Gopal, Udhayakumar, Hance, Michael W, Wing, Shane B, Argraves, Kelley M, Lundgren, Karen, Isaacs, Jennifer S · 2011 · BMC Cancer
- A phase I dose-escalation study of intravenous panobinostat in patients with lymphoma and solid tumorsSunil Sharma, Joachim Beck, Monica M Mita, Sofia Paul, Margaret M. Woo, Margaret K. T. Squier, Brian Gadbaw, Henry Miles Prince · 2013 · Investigational New Drugs
- Effects of downregulated HDAC6 expression on the proliferation of lung cancer cellsKazuo Kamemura, Akihiro Ito, Tadahiro Shimazu, Akihisa Matsuyama, Satoko Maeda, Tso‐Pang Yao, Sueharu Horinouchi, Saadi Khochbin, Minoru Yoshida · 2008 · Biochemical and Biophysical Research Communications
- Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia CellsRui Wang, Ying Li, Ping Gong, Janice Lynn Gabrilove, Samuel Waxman, Yongkui Jing · 2018 · Molecular Cancer Therapeutics
- Novel Pathophysiological Mechanisms of Thrombosis in Myeloproliferative NeoplasmsBrandi Reeves, Joan Denise Beckman · 2021 · Current Hematologic Malignancy Reports
- Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for GlioblastomaRaghupathy Vengoji, Pranita Atri, Muzafar Ahmad Macha, Parthasarathy Seshacharyulu, Naveenkumar Perumal, Kavita B. Mallya, Yutong Liu, Lynette M. Smith, Satyanarayana Rachagani, Sidharth Mahapatra et al. · 2021 · Journal of Experimental & Clinical Cancer Research
- Targeting Huntington’s disease through histone deacetylasesSteven G. Gray · 2011 · Clinical Epigenetics
- Hydroxyurea increases eNOS protein levels through inhibition of proteasome activityVladan P. Čokić, Bojana B. Beleslin‐Čokić, Constance Tom Noguchi, Alan N. Schechter · 2007 · Nitric Oxide
- SOX8 Regulates Permeability of the Blood-Testes Barrier That Affects Adult Male Fertility in the Mouse1Ajeet Pratap Singh, Connie A. Cummings, Yuji M. Mishina, Trevor Archer · 2013 · Biology of Reproduction
- Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapyMark Frederick McCarty, Simon Bernard Iloki Assanga, Lidianys María Lewis Luján · 2020 · Medical Hypotheses
- Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy MethodMadhuri Sankaranarayanapillai, William P. Tong, Qing Yuan, James A. Bankson, Hagit Dafni, William G. Bornmann, Suren Soghomonyan, Ashutosh Pal, Marc S. Ramirez, Douglas Webb et al. · 2008 · Molecular Imaging
- Investigational histone deacetylase inhibitors (HDACi) in myeloproliferative neoplasmsPrithviraj Bose, Srđan Verstovšek · 2016 · Expert Opinion on Investigational Drugs
- HDAC6 and Ovarian CancerJoshua Haakenson, Xiaohong Mary Zhang · 2013 · International Journal of Molecular Sciences
- Rational Combinations of Targeted Agents in AMLPrithviraj Bose, Steven Grant · 2015 · Journal of Clinical Medicine
- VANTAGE 095: An International, Multicenter, Open-Label Study of Vorinostat (MK-0683) in Combination With Bortezomib in Patients With Relapsed and Refractory Multiple MyelomaDavid Samuel DiCapua Siegel, Meletios Athanasios Dimopoulos, Sundar Jagannath, Hartmut Goldschmidt, Simon Durrant, Jonathan L. Kaufman, Xavier P Leleu, Arnon Nagler, Fritz C. Offner, Thorsten T. Graef et al. · 2016 · Clinical Lymphoma Myeloma & Leukemia
- Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-PathogenesisAmir Zeb, Chanin Park, Shailima DV Rampogu, Minky Son, Gihwan Lee, Keun Woo Lee · 2018 · ACS Chemical Neuroscience
- Heat-Shock Proteins in Leukemia and Lymphoma: Multitargets for Innovative Therapeutic ApproachesVincent Cabaud Gibouin, Manon Durand, Ronan Quéré, François Girodon, Carmen Garrido, Gaëtan Jégo · 2023 · Cancers
- Efficacy of Histone Deacetylase and Estrogen Receptor Inhibition in Breast Cancer Cells Due to Concerted down Regulation of AktScott Thomas, Kenneth T. Thurn, Paromita Raha, Stephanie Chen, Pamela N. Münster · 2013 · PLoS ONE
- Differential effects of binge methamphetamine injections on the mRNA expression of histone deacetylases (HDACs) in the rat striatumOluwaseyi Omonijo, Pawaris Wongprayoon, Bruce Ladenheim, Michael T. McCoy, Piyarat Govitrapong, Subramaniam Jayanthi, Jean Lud Cadet · 2014 · NeuroToxicology
- The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate CancerSonia Manca, Cole P. Frisbie, Chad A. LaGrange, Carol A. Casey, Jean-Jack M. Riethoven, Armen Petrosyan · 2018 · Molecular Cancer Research
- An overview of investigational Histone deacetylase inhibitors (HDACis) for the treatment of non-Hodgkin’s lymphomaSusmitha Apuri, Lubomir Sokol · 2016 · Expert Opinion on Investigational Drugs
- The HDAC6 Inhibitor Tubacin Induces Release of CD133+ Extracellular Vesicles From Cancer CellsOlivia S. Chao, Tim C. Chang, Maria Antonietta Di Bella, Riccardo Alessandro, Fabio Anzanello, Germana Rappa, Oscar B. Goodman, Aurelio Lorico · 2017 · Journal of Cellular Biochemistry
- PD-L1 upregulation in myeloma cells by panobinostat in combination with interferon-γMasami Iwasa, Takeshi Harada, Asuka Oda, Ariunzaya Bat‐Erdene, Jumpei Teramachi, Hirofumi Tenshin, Mohannad Ashtar, Masahiro Oura, Kimiko Sogabe, Kengo Udaka et al. · 2019 · Oncotarget
- Modulation of serine/threonine-protein phosphatase 1 (PP1) complexes: A promising approach in cancer treatmentBárbara Matos, John Howl, Cármen Jerónimo, Margarida Fardilha · 2021 · Drug Discovery Today
- Role of Selective Histone Deacetylase 6 Inhibitor ACY-1215 in Cancer and Other Human DiseasesJianglei Li, Meihong Yu, Shifeng Fu, Deliang Liu, Yuyong Tan · 2022 · Frontiers in Pharmacology
- Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6Kazuo Kamemura, Mitsutaka Ogawa, Saki Ohkubo, Yasuhiro Ohtsuka, Yu Shitara, Tohru Komiya, Satoko Maeda, Akihiro Ito, Minoru Yoshida · 2012 · FEBS Letters
- Panobinostat synergizes with bortezomib to induce endoplasmic reticulum stress and ubiquitinated protein accumulation in renal cancer cellsAkinori Sato, Takako Asano, Makoto Isono, Keiichi Ito, Tomohiko Asano · 2014 · BMC Urology
- Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1Hak-Bong Kim, Su-Hoon Lee, Jee‐Hyun Um, Won Keun Oh, Dong-Wan Kim, Chi‐Dug Kang, Sun‐Hee Kim · 2015 · Oncotarget
- Panobinostat for the treatment of acute myelogenous leukemiaFortunato Morabito, Maria Teresa Voso, Stefan Hohaus, Massimo Gentile, Ernesto Vigna, Anna Grazia Recchia, Lorenzo Iovino, E. Benedetti, Francesco Lo‐Coco, Sara Galimberti · 2016 · Expert Opinion on Investigational Drugs
- Histone Deacetylase Inhibitor Potentiates Anticancer Effect of Docetaxel via Modulation of Bcl-2 Family Proteins and Tubulin in Hormone Refractory Prostate Cancer CellsJung Jin Hwang, Yong Sook Kim, Mi Joung Kim, Dong‐Eun Kim, In Gab Jeong, Choung‐Soo Kim · 2010 · The Journal of Urology
- Suberoylanilide hydroxamic acid (SAHA) combined with bortezomib inhibits renal cancer growth by enhancing histone acetylation and protein ubiquitination synergisticallyAkinori Sato, Takako Asano, Keiichi Ito, Makoto Sumitomo, Tomohiko Asano · 2011 · British Journal of Urology
- Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancerSophia N. Ononye, Michael van Heyst, Eric M Falcone, A. Anderson, D. Wright · 2012 · Pharmaceutical Patent Analyst
- Ritonavir Interacts With Bortezomib to Enhance Protein Ubiquitination and Histone Acetylation Synergistically in Renal Cancer CellsAkinori Sato, Takako Asano, Keiichi Ito, Tomohiko Asano · 2012 · Urology
- Abrogation of Mitogen-Activated Protein Kinase and Akt Signaling by Vandetanib Synergistically Potentiates Histone Deacetylase Inhibitor-Induced Apoptosis in Human Glioma CellsEsther P. Jane, Daniel R. Premkumar, Steven O. Addo‐Yobo, Ian F. Pollack · 2009 · Journal of Pharmacology and Experimental Therapeutics
- AKT activation controls cell survival in response to HDAC6 inhibitionMaciej A. Kaliszczak, Sebastian Trousil, T Ali, Eric Ofori Aboagye · 2016 · Cell Death and Disease
- Comparative Proteomic Analysis of Chronic Myelogenous Leukemia Cells: Inside the Mechanism of Imatinib ResistanceGermano Ferrari, Roberta Pastorelli, Francesca Buchi, Elena Spinelli, Antonella Gozzini, Alberto Bosi, Valeria Santini · 2006 · Journal of Proteome Research
- Results of an abbreviated Phase Ib study of the HDAC6 inhibitor ricolinostat and paclitaxel in recurrent ovarian, fallopian tube, or primary peritoneal cancerElizabeth K. Lee, Zhenying Tan‐Wasielewski, Ursula A. Matulonis, Michael J. Birrer, Alexi A. Wright, Neil Stuart Horowitz, Panagiotis A. Konstantinopoulos, Jennifer D. Curtis, Joyce F. Liu · 2019 · Gynecologic Oncology Reports
- Immunomodulatory properties of HDAC6 inhibitors in cancer diseases: New chances for sophisticated drug design and treatment optimizationBernhard Biersack, Bianca Nitzsche, Michael Höpfner · 2022 · Seminars in Cell and Developmental Biology
- Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human Mantle Cell Lymphoma (MCL) cellsRekha Rao, Pearl Lee, Warren C. Fiskus, Yonghua Yang, Rajeshree Joshi, Yongchao Wang, Kate Buckley, Ramesh Balusu, Jianguang Chen, Sanjay Koul et al. · 2009 · Cancer Biology & Therapy
- Histone deacetylase (HDAC) 4 involvement in both Lewy and Marinesco bodiesJunko Takahashi‐Fujigasaki, Hiroto Fujigasaki · 2006 · Neuropathology and Applied Neurobiology
- STAT5 acetylationChristian Kosan, Torsten Ginter, Thorsten Heinzel, Oliver Holger Krämer · 2013 · JAK-STAT
- The histone deacetylase inhibitor chidamide induces intermittent viraemia in HIV‐infected patients on suppressive antiretroviral therapyJ H Li, Jing Ma, W Kang, C F Wang, F Bai, Keke Zhao, N Yao, Q Liu, BL Dang, BW Wang et al. · 2020 · HIV Medicine
- Down‐regulation of Thanatos‐associated protein 11 by BCR‐ABL promotes CML cell proliferation through c‐Myc expressionSatoki Nakamura, Daisuke Yokota, Lin Tan, Yasuyuki Nagata, Tomonari Takemura, Isao Hirano, Kazuyuki Shigeno, Kiyoshi Shibata, Shinya Fujisawa, Kazunori Ohnishi · 2011 · International Journal of Cancer
- Metformin Augments Panobinostat's Anti-Bladder Cancer Activity by Activating AMP-Activated Protein KinaseKazuki Okubo, Makoto Isono, Takako Asano, Akinori Sato · 2019 · Translational Oncology
- Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cellsPeng Wu, Ye Edward Tian, G Chen, Bingbao Wang, Lingli Gui, L Xi, Xiangyi Ma, Yong Fang, Tao Zhu, Dejuan Wang et al. · 2009 · Cell Death and Differentiation
- Beyond JAK inhibitor therapy in myelofibrosisOlatoyosi M. Odenike · 2013 · Hematology
- A phase 2 study of pracinostat combined with ruxolitinib in patients with myelofibrosisPrithviraj Bose, Mahesh Swaminathan, Naveen Pemmaraju, Alessandra Ferrajoli, Elias Joseph Jabbour, Naval Guastad Daver, Courtney Denton Dinardo, Yesid Alvarado, Musa E. Yilmaz, Julie Huynh-Lu et al. · 2019 · Leukemia & lymphoma/Leukemia and lymphoma
- HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor SignalingJixiang Zhang, Jazzmine M. Junigan, Ronnie The Phong Trinh, Annemieke Kavelaars, Cobi J. Heijnen, Peter M. Grace · 2022 · Journal of Neuroscience
- The role of viruses in cancer development versus cancer therapy: An oncological perspectiveHossein Javid, Alireza Sharbaf Mashhad, Shaghayegh Yazdani, Mahsa Akbari Oryani, Sanaz Akbari, Nastaran Rezagholinejad, Mahboubeh Tajaldini, Mehdi Karimi‐Shahri · 2023 · Cancer Medicine
- Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 CleavageSangkyu Park, Jeong-A Park, Jae-Hyung Jeon, Younghee Lee · 2019 · Biomolecules & Therapeutics
- Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancerPeter M. Wilson, Melissa J. LaBonte, Shelby C. Martin, Stephanie T Kuwahara, Anthony B. El-Khoueiry, Heinz‐Josef Lenz, Robert D. Ladner · 2013 · Investigational New Drugs
- Histone Deacetylase 6–Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional ActivityRubén Jiménez-Canino, Fabián Lorenzo-Díaz, Frédéric Jaisser, Nicolette Farman, Teresa Giráldez, Diego Álvarez de la Rosa · 2016 · Endocrinology
- Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding GroupsGustavo Salgado Pires, Heber Victor Tolomeu, Daniel Alencar Rodrigues, Lı́dia Moreira Lima, Carlos Alberto Manssour Fraga, Pedro de Sena Murteira Pinheiro · 2025 · Pharmaceuticals
- C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and BedsideSivakami Mylvaganam, Rebecca Earnshaw, Gregory Heymann, Suneil Kumar Kalia, Lorraine V. Kalia · 2020 · Current Neuropharmacology
- Therapy of Relapsed and Refractory Multiple MyelomaThomas M. Moehler, Hartmut Goldschmidt · 2011 · Recent results in cancer research/Recent Results in Cancer Research
- Novel Combination Treatments Targeting Chronic Myeloid Leukemia Stem CellsTareq Al Baghdadi, Rafat Abonour, H. Scott Boswell · 2011 · Clinical Lymphoma Myeloma & Leukemia
- Novel therapies in MM: from the aspect of preclinical studiesTeru Hideshima, Kenneth Carl Anderson · 2011 · International Journal of Hematology
- Critical review of non‐histone human substrates of metal‐dependent lysine deacetylasesTasha B. Toro, Terry J. Watt · 2020 · The FASEB Journal
- Ritonavir and ixazomib kill bladder cancer cells by causing ubiquitinated protein accumulationAkinori Sato, Takako Asano, Kazuki Okubo, Makoto Isono, Tomohiko Asano · 2017 · Cancer Science
- A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cellsBailin He, Qiang Wang, Xiaoli Liu, Ziyuan Lu, Jiaochan Han, Chengyun Pan, Bing Z. Carter, Qifa Liu, Na Xu, Hongsheng Zhou · 2020 · Biomedicine & Pharmacotherapy
- Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitorsHao Hu, Fei Chen, Yuhong Dong, Ming Li, Sicong Xu, Mingze Qin, Ping Gong · 2020 · European Journal of Medicinal Chemistry
- Synthesis of 2-(1 H -Indol-2-yl)acetamides via Brønsted Acid-Assisted Cyclization CascadeNicolai A. Aksenov, Дмитрий А. Аксенов, Anton A. Skomorokhov, Lidiya A. Prityko, Alexander V. Aksenov, Георгий Д. Грязнов, Michael Rubin · 2020 · The Journal of Organic Chemistry
- RETRACTED: P210 Bcr‐abl tyrosine kinase interaction with histone deacetylase 1 modifies histone H4 acetylation and chromatin structure of chronic myeloid leukaemia haematopoietic progenitorsGianluca Brusa, Elisa Zuffa, Manuela Mancini, Michela Benvenuti, Natalia Calonghi, Enza Barbieri, Maria Alessandra Santucci · 2005 · British Journal of Haematology · Retracted
- Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion KinasePascale Flandrin‐Gresta, Françoise Solly, Carmen Mariana Aanei, Jérôme Cornillon, Emmanuelle Tavernier, Nathalie Nadal, Franck Morteux, Denis Guyotat, Eric Wattel, Lydia Campos · 2012 · Oncotarget
- Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent UpdateFaria Sultana, Kesari Lakshmi Manasa, Siddiq Pasha Shaik, Srinivasa Reddy Bonam, Ähmed Kamal · 2018 · Current Medicinal Chemistry
- Lysine Acetylation is an Important Post-Translational Modification that Modulates Heat Shock Response in the Sea Cucumber Apostichopus japonicusDongxue Xu, Xuan Wang · 2019 · International Journal of Molecular Sciences
- A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast CancerHui‐Wen Chiu, Ya-Ling Yeh, Sheng‐Yow Ho, Yuan-Hua Wu, Bour-Jr Wang, Wei‐Jan Huang, Yuan‐Soon Ho, Ying‐Jan Wang, Li-Ching Chen, Shih‐Hsin Tu · 2019 · Cancers
- Impact of IL-15 and latency reversing agent combinations in the reactivation and NK cell-mediated suppression of the HIV reservoirD. Covino, M. Desimio, M. Doria · 2022 · Scientific Reports