Seto, Edward

Acetylation and deacetylation of non-histone proteins

Glozak, M. A., Sengupta, N., Zhang, X., & Seto, E. (2005) · Gene

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 1,584

Histone deacetylases and cancer

Glozak, M. A., & Seto, E. (2007) · Oncogene

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 1,031

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

Yang, X.-J., & Seto, E. (2008) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,006

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Bali, P., Pranpat, M., Bradner, J., Balasis, M., Fiskus, W., Guo, F., Rocha, K., Kumaraswamy, S., Boyapalle, S., Atadja, P., et al. (2005) · Journal of Biological Chemistry

Heat shock proteins researchHistone Deacetylase Inhibitors Research

Cited by 755

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

Villagra, A., Cheng, F., Wang, H.-W., Suarez, I., Glozak, M., Maurin, M., Nguyen, D., Wright, K. L., Atadja, P. W., Bhalla, K., et al. (2009) · Nature Immunology

T-cell and B-cell ImmunologyHistone Deacetylase Inhibitors Research

Cited by 455

The histone deacetylase-3 complex contains nuclear receptor corepressors

Wen, Y.-D., Perissi, V., Staszewski, L. M., Yang, W.-M., Krones, A., Glass, C. K., Rosenfeld, M. G., & Seto, E. (2000) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 378

Chromosomally integrated human herpesvirus 6: questions and answers

Pellett, P. E., Ablashi, D. V., Ambros, P. F., Agut, H., Caserta, M. T., Descamps, V., Flamand, L., Gautheret‐Dejean, A., Hall, C. B., Kamble, R. T., et al. (2012) · Reviews in Medical Virology

Cytomegalovirus and herpesvirus researchViral-associated cancers and disorders

Cited by 377

Histone Deacetylase 3 Interacts with and Deacetylates Myocyte Enhancer Factor 2

Grégoire, S., Xiao, L., Nie, J., Zhang, X., Xu, M., Li, J., Wong, J., Seto, E., & Yang, X.-J. (2007) · Molecular and Cellular Biology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 203

Regulation of histone deacetylase 2 by protein kinase CK2

Tsai, S.-C., & Seto, E. (2002) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 196

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

Cao, J., Sun, L., Aramsangtienchai, P., Spiegelman, N. A., Zhang, X., Huang, W., Seto, E., & Lin, H. (2019) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors Researchinterferon and immune responses

Cited by 189

Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A

Lee, H., Rezai-Zadeh, N., & Seto, E. (2004) · Molecular and Cellular Biology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 153

HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα

Zhang, M., Xiang, S., Joo, H.-Y., Wang, L., Williams, K. A., Liu, W., Hu, C., Tong, D., Haakenson, J., Wang, C., et al. (2014) · Molecular Cell

DNA Repair MechanismsHistone Deacetylase Inhibitors Research

Cited by 151

Receptor-interacting Protein 140 Directly Recruits Histone Deacetylases for Gene Silencing

Wei, L.-N., Hu, X., Chandra, D., Seto, E., & Farooqui, M. (2000) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 150

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

Cheng, F., Lienlaf, M., Perez-Villarroel, P., Wang, H.-W., Lee, C., Woan, K., Woods, D., Knox, T., Bergman, J., Pinilla-Ibarz, J., et al. (2014) · Molecular Immunology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 140

Programming and regulation of metabolic homeostasis by HDAC11

Sun, L., Marin de Evsikova, C., Bian, K., Achille, A., Telles, E., Pei, H., & Seto, E. (2018) · EBioMedicine

Histone Deacetylase Inhibitors ResearchAdipose Tissue and Metabolism

Cited by 125

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

Bagchi, R. A., Ferguson, B. S., Stratton, M. S., Hu, T., Cavasin, M. A., Sun, L., Lin, Y.-H., Liu, D., Londono, P., Song, K., et al. (2018) · JCI Insight

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 110

A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs

Cheng, F., Lienlaf, M., Wang, H.-W., Perez-Villarroel, P., Lee, C., Woan, K., Rock-Klotz, J., Sahakian, E., Woods, D., Pinilla-Ibarz, J., et al. (2014) · The Journal of Immunology

Histone Deacetylase Inhibitors ResearchT-cell and B-cell Immunology

Cited by 106

Endometriosis is characterized by a distinct pattern of histone 3 and histone 4 lysine modifications

Monteiro, J. B., Colón-Díaz, M., García, M., Gutierrez, S., Colón, M., Seto, E., Laboy, J., & Flores, I. (2014) · Reproductive Sciences

Endometriosis Research and TreatmentEpigenetics and DNA Methylation

Cited by 98

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function

Huang, J., Wang, L., Dahiya, S., Beier, U. H., Han, R., Samanta, A., Bergman, J., Sotomayor, E. M., Seto, E., Kozikowski, A. P., et al. (2017) · Scientific Reports

T-cell and B-cell ImmunologyHistone Deacetylase Inhibitors Research

Cited by 96

Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance

Bahl, S., & Seto, E. (2021) · Cellular and Molecular Life Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 82

T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model

Woods, D. M., Woan, K. V., Cheng, F., Sodré, A. L., Wang, D., Wu, Y., Wang, Z., Chen, J., Powers, J., Pinilla-Ibarz, J., et al. (2017) · Blood

T-cell and B-cell ImmunologyHistone Deacetylase Inhibitors Research

Cited by 74

HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy

Emmons, M. F., Faião-Flores, F., Sharma, R., Thapa, R., Messina, J. L., Becker, J. C., Schadendorf, D., Seto, E., Sondak, V. K., Koomen, J. M., et al. (2019) · Cancer Research

Melanoma and MAPK PathwaysHistone Deacetylase Inhibitors Research

Cited by 73

Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation

Yang, Y., Tse, A. K.-W., Li, P., Ma, Q., Xiang, S., Nicosia, S. V., Seto, E., Zhang, X., & Bai, W. (2011) · Oncogene

Prostate Cancer Treatment and ResearchHistone Deacetylase Inhibitors Research

Cited by 72