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Complexation of NAC-Derived Peptide Ligands with the C-Terminus of α-Synuclein Accelerates Its Aggregation

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Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson’s Disease

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α-Synuclein Penetrates Mucin Hydrogels Despite Its Mucoadhesive Properties

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Interaction of Alpha-Synuclein and Its Mutants with Rigid Lipid Vesicle Mimics of Varying Surface Curvature

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Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

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Missense Mutations Modify the Conformational Ensemble of the α-Synuclein Monomer Which Exhibits a Two-Phase Characteristic

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Dimerization of α-Synuclein Fragments Studied by Isothermal–Isobaric Replica-Permutation Molecular Dynamics Simulation

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Tracer development for PET imaging of proteinopathies

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Unveiling How Hydroxytyrosol Destabilizes α-Syn Oligomers Using Molecular Simulations

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Histone Post-translational Modifications in Huntington’s and Parkinson’s Diseases

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Cinnamaldehyde and Phenyl Ethyl Alcohol promote the entrapment of intermediate species of HEWL, as revealed by structural, kinetics and thermal stability studies

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Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy

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A Master Regulator of α-Synuclein Aggregation

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Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases

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α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation

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Top/Middle-Down Characterization of α-Synuclein Glycoforms

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In silico study on graphene quantum dots modified with various functional groups inhibiting α‑synuclein dimerization

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Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?

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Cyclophilin D binds to the acidic C-terminus region of α-Synuclein and affects its aggregation characteristics

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Chronic Exposure to Paraquat Induces Alpha-Synuclein Pathogenic Modifications in Drosophila

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Insights into the Interactions that Trigger the Primary Nucleation of Polymorphic α-Synuclein Dimers

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Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo

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Aggregation of a Parkinson’s Disease-Related Peptide: When Does Urea Weaken Hydrophobic Interactions?

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Products of Cu( ii )-catalyzed oxidation of α-synuclein fragments containing M 1 -D 2 and H 50 residues in the presence of hydrogen peroxide

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Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria

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The Anthocyanidin Peonidin Interferes with an Early Step in the Fibrillation Pathway of α-Synuclein and Modulates It toward Amorphous Aggregates

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E46K Mutation of α-Synuclein Preorganizes the Intramolecular Interactions Crucial for Aggregation

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Biologically Representative Lipid-Coated Gold Nanoparticles and Phospholipid Vesicles for the Study of Alpha-Synuclein/Membrane Interactions

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The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine

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Emerging Trends in Cryo-EM-based Structural Studies of Neuropathological Amyloids

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Human β-Synuclein Rendered Fibrillogenic by Designed Mutations

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Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity

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Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice

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Spinal cord and parkinsonism: Neuromorphological evidences in humans and experimental studies

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Modulation effect of filamentous phage on α-synuclein aggregation

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Remaining structures at the N‐ and C‐terminal regions of alpha‐synuclein accurately elucidated by amide‐proton exchange NMR with fitting

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Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1

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A conformation-switching fluorescent protein probe for detection of alpha synuclein oligomers

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Mechanisms and models of α-synuclein-related neurodegeneration

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Role of the p62 Protein in the Formation of Neuropathological Cytoplasmic Inclusions

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Residues 2 to 7 of α-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways

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Role of Lipids in the Pathogenesis of Parkinson’s Disease

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Exploring the Impact of Physiological C-Terminal Truncation on α-Synuclein Conformations to Unveil Mechanisms Regulating Pathological Aggregation

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Understanding the dynamics of monomeric, dimeric, and tetrameric α‐synuclein structures in water

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Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies

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α-Synuclein and tau, two targets for dementia

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Cellular Models of Alpha-Synuclein Aggregation: What Have We Learned and Implications for Future Study

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On the effect of methionine oxidation on the interplay between α-synuclein and synaptic-like vesicles

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A functional role for alpha-synuclein in neuroimmune responses

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Investigation of Intramolecular Dynamics and Conformations of α-, β- and γ-Synuclein

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Shedding light on aberrant interactions – a review of modern tools for studying protein aggregates

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Entropic Bristles Tune the Seeding Efficiency of Prion-Nucleating Fragments

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Proteome-wide landscape of solubility limits in a bacterial cell

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Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model

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