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BLOC-2, AP-3, and AP-1 Proteins Function in Concert with Rab38 and Rab32 Proteins to Mediate Protein Trafficking to Lysosome-related Organelles
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Hps5 functions in the BLOC2 complex, which in melanophores is involved in transport from early endosomes to maturating melanosomes.
“Hps5 functions in the BLOC2 complex, which in melanophores is involved in transport from early endosomes to maturating melanosomes (23, 43, 44, 85, 91).”
From Lysosome-related organelles orchestrate guanine crystal formation in pigment cells (2026) · cites this paper as [44]
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Lysosome-related organelles: driving post-Golgi compartments into specialisation
Raposo, G., Marks, M. S., & Cutler, D. F. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.05.001 · Cited by 215
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Research works printed but not linked: 53
- Dell'Angelica, 2000, Lysosome-related organelles, FASEB J., 14, 1265
- Spritz, 2003, Human and mouse disorders of pigmentation, Curr. Opin. Genet. Dev., 13, 284, 10.1016/S0959-437X(03)00059-5 · DOI
- Huizing, 2008, Disorders of lysosome-related organelle biogenesis. Clinical and molecular genetics, Annu. Rev. Genomics Hum. Genet., 9, 359, 10.1146/annurev.genom.9.081307.164303 · DOI
- Di Pietro, 2005, The cell biology of Hermansky-Pudlak syndrome. Recent advances, Traffic, 6, 525, 10.1111/j.1600-0854.2005.00299.x · DOI
- Wei, 2006, Hermansky-Pudlak syndrome. A disease of protein trafficking and organelle function, Pigment Cell Res., 19, 19, 10.1111/j.1600-0749.2005.00289.x · DOI
- Cullinane, 2011, A BLOC-1 mutation screen reveals that PLDN is mutated in Hermansky-Pudlak syndrome type 9, Am. J. Hum. Genet., 88, 778, 10.1016/j.ajhg.2011.05.009 · DOI
- Li, 2004, Murine Hermansky-Pudlak syndrome genes. Regulators of lysosome-related organelles, BioEssays, 26, 616, 10.1002/bies.20042 · DOI
- Gautam, 2006, Interaction of Hermansky-Pudlak syndrome genes in the regulation of lysosome-related organelles, Traffic, 7, 779, 10.1111/j.1600-0854.2006.00431.x · DOI
- Dell'Angelica, 2004, The building BLOC(k)s of lysosomes and related organelles, Curr. Opin. Cell Biol., 16, 458, 10.1016/j.ceb.2004.05.001 · DOI · Paper page
- Dell'Angelica, 2009, AP-3-dependent trafficking and disease. The first decade, Curr. Opin. Cell Biol., 21, 552, 10.1016/j.ceb.2009.04.014 · DOI
- Bonifacino, 2003, Signals for sorting of transmembrane proteins to endosomes and lysosomes, Annu. Rev. Biochem., 72, 395, 10.1146/annurev.biochem.72.121801.161800 · DOI · Paper page
- Peden, 2004, Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins, J. Cell Biol., 164, 1065, 10.1083/jcb.200311064 · DOI
- Raposo, 2007, Melanosomes. Dark organelles enlighten endosomal membrane transport, Nat. Rev. Mol. Cell Biol., 8, 786, 10.1038/nrm2258 · DOI
- Theos, 2005, Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes, Mol. Biol. Cell, 16, 5356, 10.1091/mbc.e05-07-0626 · DOI · Paper page
- Hurbain, 2008, Electron tomography of early melanosomes. Implications for melanogenesis and the generation of fibrillar amyloid sheets, Proc. Natl. Acad. Sci. U.S.A., 105, 19726, 10.1073/pnas.0803488105 · DOI
- Di Pietro, 2006, BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes, Mol. Biol. Cell, 17, 4027, 10.1091/mbc.e06-05-0379 · DOI
- Setty, 2007, BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles, Mol. Biol. Cell, 18, 768, 10.1091/mbc.e06-12-1066 · DOI
- Salazar, 2006, BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes, Mol. Biol. Cell, 17, 4014, 10.1091/mbc.e06-02-0103 · DOI
- Delevoye, 2009, AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis, J. Cell Biol., 187, 247, 10.1083/jcb.200907122 · DOI
- Marks, 2001, The melanosome: membrane dynamics in black and white, Nat. Rev. Mol. Cell Biol., 2, 738, 10.1038/35096009 · DOI
- Rendu, 2001, The platelet release reaction. Granules' constituents, secretion, and functions, Platelets, 12, 261, 10.1080/09537100120068170 · DOI
- Zerial, 2001, Rab proteins as membrane organizers, Nat. Rev. Mol. Cell Biol., 2, 107, 10.1038/35052055 · DOI · Paper page
- Hutagalung, 2011, Role of Rab GTPases in membrane traffic and cell physiology, Physiol. Rev., 91, 119, 10.1152/physrev.00059.2009 · DOI · Paper page
- Loftus, 2002, Mutation of melanosome protein RAB38 in chocolate mice, Proc. Natl. Acad. Sci. U.S.A., 99, 4471, 10.1073/pnas.072087599 · DOI
- Cohen-Solal, 2003, Identification and characterization of mouse Rab32 by mRNA and protein expression analysis, Biochim. Biophys. Acta, 1651, 68, 10.1016/S1570-9639(03)00236-X · DOI
- Wasmeier, 2006, Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes, J. Cell Biol., 175, 271, 10.1083/jcb.200606050 · DOI · Paper page
- Brooks, 2007, Analysis of ocular hypopigmentation in Rab38 cht/cht mice, Invest. Ophthalmol. Vis. Sci., 48, 3905, 10.1167/iovs.06-1464 · DOI
- Osanai, 2008, A mutation in Rab38 small GTPase causes abnormal lung surfactant homeostasis and aberrant alveolar structure in mice, Am. J. Pathol., 173, 1265, 10.2353/ajpath.2008.080056 · DOI
- Oiso, 2004, The rat Ruby (R) locus is Rab38. Identical mutations in Fawn-hooded and Tester-Moriyama rats derived from an ancestral Long Evans rat sub-strain, Mamm. Genome, 15, 307, 10.1007/s00335-004-2337-9 · DOI
- Ninkovic, 2008, The role of Rab38 in platelet-dense granule defects, J. Thromb. Haemost., 6, 2143, 10.1111/j.1538-7836.2008.03178.x · DOI
- Lopes, 2007, Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis, Mol. Biol. Cell, 18, 3914, 10.1091/mbc.e07-03-0268 · DOI
- Marks, 2006, Darkness descends with two Rabs, J. Cell Biol., 175, 199, 10.1083/jcb.200608058 · DOI
- Di Pietro, 2004, Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5, and HPS6, Traffic, 5, 276, 10.1111/j.1600-0854.2004.0171.x · DOI · Paper page
- Nazarian, 2008, An immunoblotting assay to facilitate the molecular diagnosis of Hermansky-Pudlak syndrome, Mol. Genet. Metab., 93, 134, 10.1016/j.ymgme.2007.09.001 · DOI
- Dell'Angelica, 2000, Molecular characterization of the protein encoded by the Hermansky-Pudlak syndrome type 1 gene, J. Biol. Chem., 275, 1300, 10.1074/jbc.275.2.1300 · DOI
- Kloer, 2010, Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9, J. Biol. Chem., 285, 7794, 10.1074/jbc.M109.069088 · DOI
- Nazarian, 2006, Reinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding protein, Biochem. J., 395, 587, 10.1042/BJ20051965 · DOI
- Ozeki, 1995, Chemical characterization of hair melanins in various coat-color mutants of mice, J. Invest. Dermatol., 105, 361, 10.1111/1523-1747.ep12320792 · DOI
- Dell'Angelica, 1999, Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the β3A subunit of the AP-3 adaptor, Mol. Cell, 3, 11, 10.1016/S1097-2765(00)80170-7 · DOI
- Dell'Angelica, 1997, β3A-adaptin, a subunit of the adaptor-like complex AP-3, J. Biol. Chem., 272, 15078, 10.1074/jbc.272.24.15078 · DOI
- Kim, 2006, The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER, J. Cell Biol., 173, 521, 10.1083/jcb.200601036 · DOI
- Valencia, 2006, Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2. Evidence for the polarized nature of melanocytes, J. Cell Sci., 119, 1080, 10.1242/jcs.02804 · DOI
- Truschel, 2009, ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane, Traffic, 10, 1318, 10.1111/j.1600-0854.2009.00955.x · DOI
- Setty, 2008, Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes, Nature, 454, 1142, 10.1038/nature07163 · DOI
- Tamura, 2009, Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes, Mol. Biol. Cell, 20, 2900, 10.1091/mbc.e08-12-1161 · DOI
- Helip-Wooley, 2007, Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5, J. Invest. Dermatol., 127, 1471, 10.1038/sj.jid.5700737 · DOI · Paper page
- Huizing, 2001, AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes, Mol. Biol. Cell, 12, 2075, 10.1091/mbc.12.7.2075 · DOI
- Tamura, 2011, Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes, J. Biol. Chem., 286, 7507, 10.1074/jbc.M110.191205 · DOI
- Gautam, 2004, The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2), J. Biol. Chem., 279, 12935, 10.1074/jbc.M311311200 · DOI
- Kobayashi, 2007, Direct interaction of tyrosinase with Tyrp1 to form heterodimeric complexes in vivo, J. Cell Sci., 120, 4261, 10.1242/jcs.017913 · DOI
- Bui, 2010, Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties, J. Biol. Chem., 285, 31590, 10.1074/jbc.M110.101584 · DOI
- Baust, 2008, Protein networks supporting AP-3 function in targeting lysosomal membrane proteins, Mol. Biol. Cell, 19, 1942, 10.1091/mbc.e08-02-0110 · DOI
- Huizing, 2009, Clinical and cellular characterization of Hermansky-Pudlak syndrome type 6, J. Med. Genet., 46, 803, 10.1136/jmg.2008.065961 · DOI
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Metadata
- Authors
- Bultema, J. J., Ambrosio, A. L., Burek, C. L., & Di Pietro, S. M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2012-06
- Volume
- 287
- Issue
- 23
- Pages
- 19550-19563
- ISSN
- 0021-9258
- Cited by
- 128
- References
- 1
- Language
- en
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