The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
REST Repression of Neuronal Genes Requires Components of the hSWI·SNF Complex
Open accessAbstract
A function of the transcription factor REST is to block the expression of neuronal phenotypic traits in non-neuronal cells. Previous studies have shown that REST-mediated repression requires histone deacetylase activity and that recruitment of deacetylases is mediated by two co-repressors, Sin3A and CoREST. In this study, we show that a repressor domain in CoREST interacts with BRG1-associated factor (BAF) 57, a component of the hSWI.SNF complex. In vivo, BAF57 occupies the neuronal sodium channel gene (Nav1.2) promoter, and targeting to this gene requires REST. In addition to BAF57, the ATPase BRG1 and BAF170, other members of the hSWI.SNF complex, are also present in the REST.CoREST repressor complex. Microinjection of specific antibodies against BRG1, BAF57, or BAF170 into Rat1 fibroblasts relieves repression of RE1 reporter genes. Together, our data suggest that ATP-dependent chromatin remodeling, as well as histone deacetylation, is needed for REST-mediated repression.
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Cites
Signaling to Chromatin through Histone Modifications
Cheung, P., Allis, C. D., & Sassone-Corsi, P. (2000) · Cell · doi:10.1016/s0092-8674(00)00118-5 · Cited by 989
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
Tong, J. K., Hassig, C. A., Schnitzler, G. R., Kingston, R. E., & Schreiber, S. L. (1998) · Nature · doi:10.1038/27699 · Cited by 692
CoREST: A functional corepressor required for regulation of neural-specific gene expression
Andrés, M. E., Burger, C., Peral-Rubio, M. J., Battaglioli, E., Anderson, M. E., Grimes, J., Dallman, J., Ballas, N., & Mandel, G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.17.9873 · Cited by 494
Self-citationWhole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae
Sudarsanam, P., Iyer, V. R., Brown, P. O., & Winston, F. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3364 · Cited by 389
Functional significance of histone deacetylase diversity
Khochbin, S., Verdel, A., Lemercier, C., & Seigneurin-Berny, D. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00174-x · Cited by 366
Humphrey, G. W., Wang, Y., Russanova, V. R., Hirai, T., Qin, J., Nakatani, Y., & Howard, B. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007372200 · Cited by 331
Cited by
Regulation of histone acetylation during memory formation in the hippocampus
Levenson, J. M., O'Riordan, K. J., Brown, K. D., Trinh, M. A., Molfese, D. L., & Sweatt, J. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402229200 · Cited by 1,131
REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis
Ballas, N., Grunseich, C., Lu, D. D., Speh, J. C., & Mandel, G. (2005) · Cell · doi:10.1016/j.cell.2005.03.013 · Cited by 950
Self-citationAn essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
Lee, M. G., Wynder, C., Cooch, N., & Shiekhattar, R. (2005) · Nature · doi:10.1038/nature04021 · Cited by 802
Epigenetic mechanisms in memory formation
Levenson, J. M., & Sweatt, J. D. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1604 · Cited by 767
A small modulatory dsRNA specifies the fate of adult neural stem cells
Kuwabara, T., Hsieh, J., Nakashima, K., Taira, K., & Gage, F. H. (2004) · Cell · doi:10.1016/s0092-8674(04)00248-x · Cited by 447
Metadata
- Authors
- Battaglioli, E., Andrés, M. E., Rose, D. W., Chenoweth, J. G., Rosenfeld, M. G., Anderson, M. E., & Mandel, G.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2002-10
- Volume
- 277
- Issue
- 43
- Pages
- 41038-41045
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1656220430
- Cited by
- 185
- References
- 6
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Battaglioli, E., Andrés, M. E., Rose, D. W., Chenoweth, J. G., Rosenfeld, M. G., Anderson, M. E., & Mandel, G. (2002). REST Repression of Neuronal Genes Requires Components of the hSWI·SNF Complex. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m205691200
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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