The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Kinetic Instability of p53 Core Domain Mutants
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In the citing paper
“Further experiments revealed that CDB3 could bind to G245S and R249S structural mutants,508 restore conformational folding,509 improve the affinity of the β-sheet I195T mutant to DNA, and restore the transcriptional activation function of p53 (R175H, R237H).”
From Targeting p53 pathways: mechanisms, structures, and advances in therapy (2023) · cites this paper as [509]
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Citations
Cites
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
Cho, Y., Gorina, S., Jeffrey, P. D., & Pavletich, N. P. (1994) · Science · doi:10.1126/science.8023157 · Cited by 2,551
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
Bykov, V. J. N., Issaeva, N., Shilov, A., Hultcrantz, M., Pugacheva, E., Chumakov, P., Bergman, J., Wiman, K. G., & Selivanova, G. (2002) · Nature Medicine · doi:10.1038/nm0302-282 · Cited by 1,067
Research works printed but not linked: 13
- Bargonetti, 2002, Curr. Opin. Oncol., 14, 86, 10.1097/00001622-200201000-00015 · DOI · Paper page
- Ryan, 2001, Curr. Opin. Cell Biol., 13, 332, 10.1016/S0955-0674(00)00216-7 · DOI · Paper page
- Hupp, 2000, Biochem. J., 352, 1, 10.1042/bj3520001 · DOI
- Lane, 2002, Trends Mol. Med., 8, S38, 10.1016/S1471-4914(02)02309-2 · DOI
- Bullock, 2000, Oncogene, 19, 1245, 10.1038/sj.onc.1203434 · DOI · Paper page
- Bullock, 2001, Nat. Rev. Cancer, 1, 68, 10.1038/35094077 · DOI · Paper page
- Friedler, 2002, Proc. Natl. Acad. Sci. U. S. A., 99, 937, 10.1073/pnas.241629998 · DOI · Paper page
- Foster, 1999, Science, 286, 2507, 10.1126/science.286.5449.2507 · DOI · Paper page
- Bullock, 1997, Proc. Natl. Acad. Sci. U. S. A., 94, 14338, 10.1073/pnas.94.26.14338 · DOI · Paper page
- Hansson, 2002, Proc. Natl. Acad. Sci. U. S. A., 99, 10305, 10.1073/pnas.122347199 · DOI
- Parker, 1977, Biopolymers, 16, 2533, 10.1002/bip.1977.360161115 · doi:10.1002/bip.1977.360161115
- Nikolova, 2000, EMBO J., 19, 370, 10.1093/emboj/19.3.370 · DOI · Paper page
- Butler, 2003, Biochemistry, 42, 2396, 10.1021/bi026635n · DOI · Paper page
Cited by
Targeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
Targeting mutant p53 for efficient cancer therapy
Bykov, V. J. N., Eriksson, S. E., Bianchi, J., & Wiman, K. G. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.109 · Cited by 889
Reactivation of mutant p53: molecular mechanisms and therapeutic potential
Selivanova, G., & Wiman, K. G. (2007) · Oncogene · doi:10.1038/sj.onc.1210295 · Cited by 186
Solution structure of p53 core domain: Structural basis for its instability
Cañadillas, J. M. P., Tidow, H., Freund, S. M. V., Rutherford, T. J., Ang, H. C., & Fersht, A. R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510941103 · Cited by 174
Self-citation
Metadata
- Authors
- Friedler, A., Veprintsev, D. B., Hansson, L. O., & Fersht, A. R.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2003-06
- Volume
- 278
- Issue
- 26
- Pages
- 24108-24112
- ISSN
- 0021-9258
- Cited by
- 133
- References
- 2
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- creativecommons.org/licenses/by/4.0/ (vor, 6340 d)
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- CoChat. (2026). Citation check: Kinetic Instability of p53 Core Domain Mutants. https://app.cochat.ai/papers/10.1074/jbc.m302458200
- The paper
- Friedler, A., Veprintsev, D. B., Hansson, L. O., & Fersht, A. R. (2003). Kinetic Instability of p53 Core Domain Mutants. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m302458200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
