Inhibition of Hypoxia-inducible Factor (HIF) Hydroxylases by Citric Acid Cycle Intermediates

Targeting HIF-1 for cancer therapy

Semenza, G. L. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1187 · Cited by 6,717

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation

Jaakkola, P., Mole, D. R., Tian, Y.-M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A. V., Hebestreit, H. F., Mukherji, M., Schofield, C. J., et al. (2001) · Science · doi:10.1126/science.1059796 · Cited by 5,535

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S., & Kaelin Jr., W. G. (2001) · Science · doi:10.1126/science.1059817 · Cited by 4,735

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Epstein, A. C. R., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00507-4 · Cited by 3,333

A conserved family of prolyl-4-hydroxylases that modify HIF

Bruick, R. K., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1066373 · Cited by 2,549

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., & Gottlieb, E. (2005) · Cancer Cell · doi:10.1016/j.ccr.2004.11.022 · Cited by 2,108

Oxygen sensing by HIF hydroxylases

Schofield, C. J., & Ratcliffe, P. J. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1366 · Cited by 2,068

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

The Multiple Leiomyoma Consortium (2002) · Nature Genetics · doi:10.1038/ng849 · Cited by 1,635

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

Lando, D., Peet, D. J., Whelan, D. A., Gorman, J. J., & Whitelaw, M. L. (2002) · Science · doi:10.1126/science.1068592 · Cited by 1,558

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Lando, D., Peet, D. J., Gorman, J. J., Whelan, D. A., Whitelaw, M. L., & Bruick, R. K. (2002) · Genes & Development · doi:10.1101/gad.991402 · Cited by 1,550

Time-Course Investigation of Small Molecule Metabolites in MAP-Stored Red Blood Cells Using UPLC-QTOF-MS

Zhou, Y., Meng, Z., Gan, H. K., Zheng, Y., Zhu, X., Wu, Z., Li, J., Gu, R., & Dou, G. (2018) · Molecules · doi:10.3390/molecules23040923 · Cited by 7

Anaerobic Microorganisms from Human Microbiota Produce Species-Specific Exometabolites Important in Heath and Disease

Beloborodova (2013) · Global Journal of Pathology and Microbiology · doi:10.14205/2310-8703.2013.01.02.1 · Cited by 7

A metabonomic analysis on health effects of drinking water on male mice (Mus musculus)

Zhang, Y., Wu, B., Zhang, Z., & Cheng, S. (2011) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2011.03.077 · Cited by 7

Short-term sustained hypoxia distinctly affects subpopulations of carotid body glomus cells from rats

Spiller, P. F., Morgan, H. J. N., Navegantes, L. C. C., Machado, B. H., da Silva, M. P., & Moraes, D. J. A. (2025) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00967.2024 · Cited by 6

Cancer Metabolism and Its Therapeutic Implications

Logsdon, W. L. C. D., & Abbruzzese, J. L. (2013) · Journal of Cell Science & Therapy · doi:10.4172/2157-7013.1000143 · Cited by 6

Inhibition of HIF-prolyl 4-hydroxylases as a promising approach to the therapy of cardiometabolic diseases

Айтбаев, К. А., Murkamilov, I. T., & Fomin, V. V. (2018) · Terapevticheskii arkhiv · doi:10.26442/terarkh201890886-94 · Cited by 6

Competitive HIF Prolyl Hydroxylase Inhibitors Show Protection against Oxidative Stress by a Mechanism Partially Dependent on Glycolysis

Bergström, A., Fog, K., Sager, T. N., Bruun, A. T., & Thirstrup, K. (2012) · ISRN Neuroscience · doi:10.1155/2013/598587 · Cited by 6

Enzymes involved in hypoxia response : characterization of the in vivo role of HIF-P4H-2 in mouse heart, of a novel P4H in human and zebrafish and of the catalytic properties of FIH

Hyvärinen, J. (2010) · Cited by 6

Case report: response to immunotherapy and association with the fh gene in hereditary leiomyomatosis and renal cell cancer-associated renal cell cancer

Gao, F., Gu, D., Zhang, H., Shi, C., Du, F., Zheng, B. J., Wu, H., & Zhao, Y. (2024) · BMC Medical Genomics · doi:10.1186/s12920-024-01957-w · Cited by 5

Tumor microenvironment and metabolic reprogramming: Unraveling the complex interplay in gastrointestinal tumor liver metastasis

Wang, S., Ma, Z., Lv, L., Qian, Y., Liu, S., & Lu, Y. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.105001 · Cited by 5

Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism

Ala‐Nisula, T., Sah‐Teli, S. K., Ronkainen, V., Dimova, E. Y., & Koivunen, P. (2023) · FEBS Letters · doi:10.1002/1873-3468.14666 · Cited by 5

The cytoprotective effect of Gymnema inodorum leaf extract against hypoxia-induced cardiomyocytes injury

Surinkaew, S., Sun, D., Kooltheat, N., Boonhok, R., Somsak, V., & Kumphune, S. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35846 · Cited by 5

Energotropic Effects of Intermittent Hypoxia: Role of Succinate-Dependent Signaling

Lukyanova, L. D., Kirova, Y. I., & Germanova, E. L. (2012) · Springer eBooks · doi:10.1007/978-1-4471-2906-6_20 · Cited by 5

Hypoxia Inducible Factor-1 as a Therapeutic Target in Cerebral Ischemia

Aguilera, P., Vázquez‐Contreras, E., Gómez, C., & Cardenas, M. (2009) · Current Signal Transduction Therapy · doi:10.2174/157436209789057458 · Cited by 5

Pyrithione Zn selectively inhibits hypoxia-inducible factor prolyl hydroxylase PHD3

Na, Y.-R., Woo, D. J., Kim, S. Y., & Yang, E. G. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.02.115 · Cited by 5

Kinetic Analysis of HIF Prolyl Hydroxylases

Koivunen, P., & Myllyharju, J. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7665-2_2 · Cited by 5

α-Tocopherol Acetate Attenuates Mitochondrial Oxygen Consumption and Maintains Primitive Cells within Mesenchymal Stromal Cell Population

Loncaric, D., Rodríguez, L., Debeissat, C., Touya, N., Labat, V., Villacreces, A., Bouzier‐Sore, A., Pasquet, J., de la Grange, P. B., Vlaski‐Lafarge, M., et al. (2021) · Stem Cell Reviews and Reports · doi:10.1007/s12015-020-10111-9 · Cited by 8

Pancreatic cancer epigenetics: adaptive metabolism reprograms starving primary tumors for widespread metastatic outgrowth

Franco, A., Duryea, J., & McDonald, O. G. (2023) · Cancer and Metastasis Reviews · doi:10.1007/s10555-023-10116-z · Cited by 5

Evidence for inhibition of HIF-1α prolyl hydroxylase 3 activity by four biologically active tetraazamacrocycles

Cao, J., Geng, Z., Ma, X., Wen, J., Yin, Y., & Wang, Z. (2012) · Organic & Biomolecular Chemistry · doi:10.1039/c2ob07076f · Cited by 5

Mechanism Governing Human Kappa-Opioid Receptor Expression under Desferrioxamine-Induced Hypoxic Mimic Condition in Neuronal NMB Cells

Babcock, J., Herrera, A. M., Coricor, G., Karch, C., Liu, A., Rivera-Gines, A., & KO, J. L. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18010211 · Cited by 5

Dimethyl fumarate for ischemic stroke

Kunze, R. (2017) · Oncotarget · doi:10.18632/oncotarget.15357 · Cited by 5

Hypoxia-inducible factor prolyl 4-hydroxylase-2 in cardiac and skeletal muscle ischemia and metabolism

Karsikas, S. (2015) · Cited by 4

Metabolomic and molecular analysis reveals multiple pathways of TBBPA-induced developmental toxicity in zebrafish embryos

Xu, Q., Gan, R., Wang, Q., Cheng, P. C., Hu, Z., & Wang, J. (2025) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2025.117295 · Cited by 4

How do immunometabolites shape bacterial infections?

Gowdy, G., & Prince, A. S. (2026) · PLoS Biology · doi:10.1371/journal.pbio.3003585 · Cited by 4

Lactate and lactylation in macrophage polarization of sepsis

Sun, J., Zhang, M., Zhang, L., Zhang, X., & Zhang, J. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1662444 · Cited by 4

Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation

da Silva-Ferreira, S., Duarte‐Oliveira, C., Antunes, D., Barbosa-Matos, C., Mendes‐Frias, A., Torrado, E., Costa, S., Silvestre, R., Cunha, C., & Carvalho, A. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1005839 · Cited by 4

What do stimulated beta cells have in common with cancer cells?

Marhl, M. (2024) · Biosystems · doi:10.1016/j.biosystems.2024.105257 · Cited by 4

Influence of cell bioenergetics on host-pathogen interaction in the lung

Lohia, G. K., & Riquelme, S. A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1549293 · Cited by 4

The Effect of Lentiviral Vector-Mediated RNA Interference Targeting Hypoxia-Inducible Factor 1α on the Uptake of Fluorodeoxyglucose ( 18 F) in the Human Pancreatic Cancer Cell Line, Patu8988

Fan, G., Bo, J., Wan, R., Peng, M., Luan, Y., Deng, M., & Xu, L. (2015) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2014.1700 · Cited by 4

Modeling dioxygenase enzyme kinetics in familial paraganglioma

Peters, J. P., Her, Y. F., & Maher, L. J. (2015) · Biology Open · doi:10.1242/bio.013623 · Cited by 4

Mitochondrial Signaling in Hypoxia

Lukyanova, L. D. (2013) · Open Journal of Endocrine and Metabolic Diseases · doi:10.4236/ojemd.2013.33029 · Cited by 4

Revascularization of Wounds: The Oxygen-Hypoxia Paradox

Hunt, T. K., Gimbel, M. L., & Sen, C. K. (2008) · Springer eBooks · doi:10.1007/978-0-387-71518-6_46 · Cited by 4

The Dual Role of Hypoxia-Inducible Factor-1 in Ischemic Stroke: Neuroprotection and Blood-Brain Barrier Disruption

Zhang, Z. (2014) · KU ScholarWorks (The University of Kansas) · Cited by 4

Increase in plasma succinate is associated with aerobic lactate production in a model of endotoxic shock

Ruiz, J. D. C., Sánchez, J. I. A., Fernández, J. J. D., Díaz‐Brochero, C., & Martínez, L. (2025) · Experimental Physiology · doi:10.1113/ep092109 · Cited by 3

Hyperglycemia in sepsis

Wang, T., Gong, B., Shi, K., Hu, G., Sun, L., & Xu, Y. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120702 · Cited by 3

Hypoxia-inducible factor prolyl 4-hydroxylase-2 in Tibetan high-altitude adaptation, extramedullary erythropoiesis and skeletal muscle ischemia

Myllymäki, M. (2016) · Cited by 3

Therapeutic Potential of High Dose Vitamin C in Cancer: Mechanisms, Clinical Evidence and Future Directions

Singh, R., Parchwani, D. N., Sharma, G., & Sharma, P. (2025) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-025-01341-0 · Cited by 3

A Survey of the Metabolic Landscape of the Developing Cerebellum at Single-Cell Resolution

Krycer, J. R., & Nayler, S. (2022) · The Cerebellum · doi:10.1007/s12311-022-01415-2 · Cited by 3

Glucose deprivation impairs hypoxia-inducible factor-1α synthesis

Hubert, M., Stuart, S. E., & Ohh, M. (2024) · Discover Oncology · doi:10.1007/s12672-024-01484-1 · Cited by 3

Glutamine-dependent effects of nitric oxide on cancer cells subjected to hypoxia-reoxygenation

Xing, D., Benavides, G. A., Johnson, M. S., Tian, R., Barnes, S., & Darley-Usmar, V. M. (2022) · Nitric Oxide · doi:10.1016/j.niox.2022.11.003 · Cited by 3

Organ preservation solutions attenuate accumulation and nuclear translocation of hypoxia‐inducible factor‐1α in the hepatoma cell line HepG2

Paddenberg, R., Howold, N., Hoger, C., Janßen, H., Grau, V., & Kummer, W. (2009) · Cell Biochemistry and Function · doi:10.1002/cbf.1608 · Cited by 3

Adult Head and Neck Sarcomas: Rare Localization with Difficult Therapeutic Management

Oualla, K. (2013) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.1000248 · Cited by 3

Early Events in Diabetic Retinopathy and Intervention Strategies

Tsin, A. T. C., & Grigsby, J. G. (2018) · InTech eBooks · doi:10.5772/intechopen.69906 · Cited by 3

Hereditary leiomyomatosis and renal cell cancer syndrome: A novel mutation in the FH gene

Tsagoudis, K., Magiera, I., Haverkamp, T., Drebber, U., Agaimy, A., & Tantcheva‐Poór, I. (2017) · The Journal of Dermatology · doi:10.1111/1346-8138.13955 · Cited by 3

In SilicoModeling of Angiogenesis at Multiple Scales: From Nanoscale to Organ System

Qutub, A. A., Gabhann, F. M., Karagiannis, E. D., & Popel, A. S. (2010) · Wiley eBooks · doi:10.1002/9780470579831.ch10 · Cited by 3

The anti-angiogenic compound dimethyl fumarate inhibits the serine synthesis pathway and increases glycolysis in endothelial cellsPreprint

Ocaña, M. C., Yang, C., Bernal, M., Martínez-Poveda, B., Vu, H., Cárdenas, C., DeBerardinis, R. J., Quesada, A. R., & Medina, M. Á. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.13.472337 · Cited by 3

Effects of SclR on metabolite production in Aspergillus oryzae

Jin, F., Wang, B., Zhang, Z. M., Zhuang, M., Jin, L. H., Yu, X. Y., & Zhu, Y. J. (2019) · SDRP Journal of Food Science & Technology · doi:10.25177/jfst.4.2.ra.476 · Cited by 2

Chemical Compounds Targeting DNA Methylation and Hydroxymethylation

Belle, R., Kawamura, A., & Arimondo, P. B. (2019) · Topics in medicinal chemistry · doi:10.1007/7355_2019_76 · Cited by 2

Therapeutic Strategies that Target the HIF System

Cook, K. M., & Schofield, C. J. (2008) · Springer eBooks · doi:10.1007/978-0-387-71518-6_32 · Cited by 2

MiRNA and Proline Metabolism in Cancer

Liu, W., & James, M. A. (2013) · InTech eBooks · doi:10.5772/55139 · Cited by 2

Angiogenesis, Arteriogenesis, and Mitochondrial Dysfunction

McMurtry, M. S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-5930-9_15 · Cited by 2

Azole derivatives as novel non-iron-chelating inhibitors of prolyl hydroxylase 3 for HIF-1 activation

Cao, J., Ma, X., Wang, X., Wang, X., Zhang, Z., Geng, Z., & Wang, Z. (2013) · MedChemComm · doi:10.1039/c3md00117b · Cited by 2

Novel Dioxygenases, HIF-α Specific Prolyl-hydroxylase and Asparanginyl-hydroxylase: O2 Switch for Cell Survival

Park, H. (2008) · Toxicological Research · doi:10.5487/tr.2008.24.2.101 · Cited by 2

A suppressor of dioxygenase inhibition in a yeast model of SDH deficiency

Beimers, W. F., Braun, M., Schwinefus, K., Pearson, K., Wilbanks, B. A., & Maher, L. J. (2022) · Endocrine Related Cancer · doi:10.1530/erc-21-0349 · Cited by 2

Hypoxia-inducible Factors and the Prevention of Acute Organ Injury

Heyman, S. N., Rosen, S., & Rosenberger, C. (2011) · Annual update in intensive care and emergency medicine · doi:10.1007/978-3-642-18081-1_4 · Cited by 2

Adaptation and stress defence in intertidal and subtidal Antarctic limpets (Nacella concinna): A study of the plasticity of molecular and biochemical stress response in Antarctic invertebrates.

Weihe, E. (2009) · State and University Library Bremen · Cited by 2

The role of ascorbate in the regulation of HIF-1 in cancer cells

Kuiper, C. (2013) · Otago University Research Archive (University of Otago) · Cited by 2

MOLECULAR AND CLINICAL CHARACTERISTICS OF TRICARBOXYLIC ACID CYCLE-ASSOCIATED TUMORS

Lehtonen, H. J. (2008) · Työväentutkimus Vuosikirja · Cited by 2

Modification of Cysteine Residues in Protein by Endogenous Oxidants and Electrophiles

Frizzell, N., & Baynes, J. (2009) · Wiley eBooks · doi:10.1002/9783527628100.ch2 · Cited by 2

Enhancing spermatogonial stem cell differentiation: The role of alpha-ketoglutarate in in-Vitro cultures

Jahanbakhsh, M., Mirzapour, T., Asgari, F., Fadakar, H., Ghasemian, F., & Koruji, M. (2025) · Theriogenology · doi:10.1016/j.theriogenology.2025.02.005 · Cited by 1

Expanding indications for sodium fumarate anti-hypoxia infusion solution in kidney cancer surgery: literature review

Popov, S. V., Dunaev, A., Guseinov, R. G., Сивак, К. В., Lelyavina, Т. А., Potapova, E., Vinokurov, A. Y., Bunenkov, N. S., Shmidt, I. O., Grushevskiy, R. O., et al. (2025) · Cancer Urology · doi:10.17650/1726-9776-2025-21-2-167-179 · Cited by 1

The Ergogenic Potential of Succinic Acid in Exercise Performance and Post-Exercise Recovery: A Systematic Review

Jędrejko, K., Catlin, O., Jędrejko, M., Muszyńska, B., Bat, I., Kleiner, S. M., Granda, D., Pokrywka, A., & Jäger, R. (2026) · Nutrients · doi:10.3390/nu18050870 · Cited by 1

Immune drivers of venous thrombosis: orchestrating initiation, formation, and resolution within the hypoxic microenvironment

Yin, J., Zhu, E., Zheng, X., Ha, X., & Li, B. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1801442 · Cited by 1

Succinate-mediated metabolic alterations and signaling in RA: mechanisms and therapeutic implications

Fan, Y., Wang, N., Zhao, C., & Zhang, Z. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1842560 · Cited by 1

Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active

Brasnett, A., Pfeffer, I., Brewitz, L., Chowdhury, R., Nakashima, Y., Tumber, A., McDonough, M. A., & Schofield, C. J. (2021) · Angewandte Chemie · doi:10.1002/ange.202103711 · Cited by 1

Alpha-ketoglutarate enhances adipose-derived stem cells survival in wound healing by hypoxia-inducible factor 1-alpha-mediated redox homeostasis and glycogen-dependent bioenergetics

Dilimulati, D., Dilimulati, D., & Cui, L. (2026) · World Journal of Stem Cells · doi:10.4252/wjsc.v18.i2.113694 · Cited by 1

Glutamine and Cancer Immunosuppression

Hammami, I., & Jolicoeur, M. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1932-1_36 · Cited by 1

Intermediarios del ciclo de Krebs en sepsis: una revisión sistemática

Ruiz, J. D., Fernández, J. J. D., Sánchez, J. I. A., Alfonso, S. I. L., Ocampo-Posada, M., & Martínez, L. (2020) · Acta Colombiana de Cuidado Intensivo · doi:10.1016/j.acci.2020.02.002 · Cited by 1

Reciprocal Crosstalk Between Angiogenesis and Metabolism

Laurent, G., & Mechta‐Grigoriou, F. (2014) · Springer eBooks · doi:10.1007/978-2-8178-0466-8_10 · Cited by 1

Inflammatory response and minimized cardiopulmonary bypass

Olivencia-Yurvati, A. H., & Mallet, R. T. (2012) · Elsevier eBooks · doi:10.1533/9780857096029.1.86 · Cited by 1

Effect of sodium succinate on oxidative stress in erythrocytes during physical loading

Hunina, L. M. (2012) · Fìzìologìčnij žurnal · doi:10.15407/fz57.06.071 · Cited by 1

Hypoxic Response and Associated Diseases

Flashman, E., Loenarz, C., & Schofield, C. J. (2008) · Wiley eBooks · doi:10.1002/9780470048672.wecb232 · Cited by 1

DEFECTS IN TRICARBOXYLIC ACID CYCLE ENZYMES FUMARATE HYDRATASE AND SUCCINATE DEHYDROGENASE IN CANCER

Ylisaukko‐oja, S. K. (2007) · Työväentutkimus Vuosikirja · Cited by 1

The role of Mcl-1 in the response of human colorectal cancer cells to treatment with dichloroacetate

Delaney, L. M. (2013) · The Atrium (University of Guelph) · Cited by 1

Role of microenvironment on neuroblastoma SK-N-AS SDHB silenced cell metabolism and function

Rapizzi, E., Fucci, R., Giannoni, E., Canu, L., Richter, S., Cirri, P., & Mannelli, M. (2015) · Endocrine Abstracts · doi:10.1530/endoabs.37.oc8.2 · Cited by 1

αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolismPreprint

Matias, M. I., Yong, C. S. M., Foroushani, A. B. K., Sezgin, E., Levental, K. R., Talebi, A., Mongellaz, C., Dehair, J., Wong, M., Kinet, S., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.24.256560 · Cited by 1

Nutritional interventions in age‐related genetic and epigenetic instability and cancer

Ong, T. P., & Loureiro, A. P. D. M. (2015) · Wiley eBooks · doi:10.1002/9781118823408.ch4 · Cited by 1

Mitochondrial Complex II in Cancer

Kľučková, K., Neužil, J., & Rohlena, J. (2014) · Springer eBooks · doi:10.1007/978-94-017-8984-4_4

THE UNDERLYING MECHANISM(S) OF FASTING INDUCED NEUROPROTECTION AFTER MODERATE TRAUMATIC BRAIN INJURY

Davis, L. M. (2008) · UKnowledge (University of Kentucky)

The regulation of hypoxia-inducible factor (HIF-1) and the role of HIF-1 in C. elegans longevity

Zhai, Z. (2010) · Iowa State University Digital Repository (Iowa State University) · doi:10.31274/etd-180810-2485

The role of EBNA binding proteins in cell transformation

Darekar, S. D. (2013) · Figshare

A systems biology approach to target identification using three-dimensional multi-cellular tumour spheroids (MCTS). Regio-specific molecular dissection of gene expression, protein expression and functional activity in 3D MCTS.

McMahon, K. M. (2011) · Bradford Scholars (University of Bradford)

The relationship between HIF-1α and autophagy activity in the hypoxic environment of breast cancer

Mills, J. (2013) · SUNScholar (Stellenbosch University)

MATERNAL OBESITY AND OXIDATIVE STRESS IN THE FETUS: MECHANISMS UNDERLYING EARLY LIFE SHIFTS IN SKELETAL MUSCLE METABOLISM

Boyle, K. E., & Friedman, J. E. (2011) · Fetal and Maternal Medicine Review · doi:10.1017/s0965539511000118

Genes Encoding Mitochondrial Enzyme Succinate Dehydrogenase Provide More Power for Breast Cancer Risk Assessment

Orloff, M. S., & Eng, C. (2009) · Breast Diseases A Year Book Quarterly · doi:10.1016/s1043-321x(09)79232-x

Disulfide bond formation - the missing link between the HR and the UPR?

Luukas, M. J. (2011)

The Effect of Hypoxia Inducible Factor-1 on the Expression of the Coinhibitory Ligands B7-H3 and B7-H1 in Cancer: Relevance to Cancer Immune Escape

Smallwood, C. A. (2012) · QSpace (Queen's University Library)

Red Grain Sorghum Whole Kernel Crude Lipid Protects Energy Metabolism And Short Chain Fatty Acid Profile In A Hamster Model To Minimize Intestinal Stress Caused By A High Fat Diet

Qiu, H. (2017) · Lincoln (University of Nebraska)

Peer Review #1 of "Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors (v0.1)"

(2019) · PeerJ · doi:10.7287/peerj.6309v0.1/reviews/1

Peer Review #3 of "Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors (v0.1)"

(2019) · PeerJ · doi:10.7287/peerj.6309v0.1/reviews/3

Peer Review #3 of "Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors (v0.2)"

(2019) · PeerJ · doi:10.7287/peerj.6309v0.2/reviews/3

Investigating Covid- 19 and Prophylactive Measures to Contain Spread of the Disease

Mustapha, B., & Usman, R. Z. (2021) · Journal of Biology Agriculture and Healthcare · doi:10.7176/jbah/11-4-05

Faculty Opinions recommendation of Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Rouse, B. T. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717996838.793474112

Peer Review #2 of "Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors (v0.2)"

(2019) · PeerJ · doi:10.7287/peerj.6309v0.2/reviews/2

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