Evolution of Differences in Transport Function in Slc11a Family Members

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166 · see citing works

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

Gietz, R. D., & Sugino, A. (1988) · Gene · doi:10.1016/0378-1119(88)90185-0 · Cited by 2,901 · see citing works

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

Fleming, M. D., Trenor, C. C., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., & Andrews, N. C. (1997) · Nature Genetics · doi:10.1038/ng0897-383 · Cited by 1,159 · see citing works

Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

Vidal, S. M., Malo, D., Vogan, K., Skamene, E., & Gros, P. (1993) · Cell · doi:10.1016/0092-8674(93)90135-d · Cited by 1,104 · see citing works

<i>Nramp</i> <i>2</i> is mutated in the anemic Belgrade ( <i>b</i> ) rat: Evidence of a role for Nramp2 in endosomal iron transport

Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D., & Andrews, N. C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1148 · Cited by 936 · see citing works

Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases

Strausak, D., Mercer, J. F. B., Dieter, H. H., Stremmel, W., & Multhaup, G. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00454-3 · Cited by 508 · see citing works

Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin

Knutson, M. D., Oukka, M., Koss, L. M., Aydemir, F., & Wessling-Resnick, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409409102 · Cited by 479 · see citing works

Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.

Canonne-Hergaux, F., Gruenheid, S., Ponka, P., & Gros, P. (1999) · Blood · doi:10.1182/blood.v93.12.4406 · Cited by 451 · see citing works

Natural Resistance to Infection with Intracellular Pathogens: The <i>Nramp1</i> Protein Is Recruited to the Membrane of the Phagosome

Gruenheid, S., Pinner, E., Desjardins, M., & Gros, P. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.4.717 · Cited by 428 · see citing works

Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae

MacDiarmid, C. W., Gaither, L. A., & Eide, D. (2000) · The EMBO Journal · doi:10.1093/emboj/19.12.2845 · Cited by 389 · see citing works

Natural Resistance to Intracellular Infections

Jabado, N., Jankowski, A., Dougaparsad, S., Picard, V., Grinstein, S., & Gros, P. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.9.1237 · Cited by 372 · see citing works

The molecular basis of copper-transport diseases

Mercer, J. F. B. (2001) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(01)01920-7 · Cited by 297 · see citing works

Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane

Forbes, J. R., & Gros, P. (2003) · Blood · doi:10.1182/blood-2003-02-0425 · Cited by 288 · see citing works

Identification and characterization of a second mouse Nramp gene

Gruenheid, S., Cellier, M. F., Vidal, S. M., & Gros, P. (1995) · Genomics · doi:10.1016/0888-7543(95)80053-o · Cited by 287 · see citing works

Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin

Delaby, C., Pilard, N., Gonçalves, A. S., Beaumont, C., & Canonne-Hergaux, F. (2005) · Blood · doi:10.1182/blood-2005-06-2398 · Cited by 283 · see citing works

Rapid and efficient site-directed mutagenesis by single-tube 'megaprimer' PCR method

Ke, S. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.16.3371 · Cited by 253 · see citing works

Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression.

Cellier, M. F., Govoni, G. R., Vidal, S. M., Kwan, T., Groulx, N., Liu, J., Sanchez, F., Skamene, E., Schurr, E., & Gros, P. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.5.1741 · Cited by 245 · see citing works

SLC11A1 (formerly NRAMP1) and disease resistance. Microreview

Blackwell, J. M., Goswami, T., Evans, C. A., Sibthorpe, D., Papo, N., White, J. K., Searle, S., Miller, E. N., Peacock, C. S., Mohammed, H., et al. (2001) · Cellular Microbiology · doi:10.1046/j.1462-5822.2001.00150.x · Cited by 242 · see citing works

DMT1: Which metals does it transport?

Garrick, M. D., Singleton, S. T., Vargas, F. P., Kuo, H., Zhao, L., Knöpfel, M., Davidson, T. L., Costa, M., Paradkar, P. N., Roth, J. A., et al. (2006) · Biological Research · doi:10.4067/s0716-97602006000100009 · Cited by 238 · see citing works

Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages

Knutson, M. D., Vafa, M. R., Haile, D. J., & Wessling-Resnick, M. (2003) · Blood · doi:10.1182/blood-2003-04-1250 · Cited by 227 · see citing works

Natural-resistance-associated macrophage protein 1 is an H+/bivalent cation antiporter

GOSWAMI, T., BHATTACHARJEE, A., BABAL, P., SEARLE, S., MOORE, E., LI, M., & BLACKWELL, J. M. (2001) · Biochemical Journal · doi:10.1042/bj3540511 · Cited by 218 · see citing works

Managed care for viruses

Crystal, R. G. (1997) · Nature Medicine · doi:10.1038/nm0497-383 · Cited by 205 · see citing works

Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function

Ellis, C. D., Wang, F., MacDiarmid, C. W., Clark, S., Lyons, T., & Eide, D. J. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200401157 · Cited by 198 · see citing works

Expansion of the Hox gene family and the evolution of chordates.

Pendleton, J. W., Nagai, B. K., Murtha, M. T., & Ruddle, F. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.13.6300 · Cited by 175 · see citing works

Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mkmice

Canonne-Hergaux, F., Zhang, A.-S., Ponka, P., & Gros, P. (2001) · Blood · doi:10.1182/blood.v98.13.3823 · Cited by 169 · see citing works

Localisation of Nramp1 in macrophages: Modulation with activation and infection

Searle, S., Bright, N. A., Roach, T. I. A., Atkinson, P. G. P., Barton, C. H., Meloen, R. H., & Blackwell, J. M. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.19.2855 · Cited by 158 · see citing works

Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins

Hettema, E. H., Taubas, J. V., & Pelham, H. R. B. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600137 · Cited by 157 · see citing works

Role of Iron in<i>Nramp1</i>-Mediated Inhibition of Mycobacterial Growth

Zwilling, B. S., Kuhn, D. E., Wikoff, L., Brown, D., & Lafuse, W. (1999) · Infection and Immunity · doi:10.1128/iai.67.3.1386-1392.1999 · Cited by 155 · see citing works

Yeast lacking superoxide dismutase. Isolation of genetic suppressors.

Liu, X. F., Elashvili, I., Gralla, E. B., Valentine, J. S., Lapinskas, P. J., & Culotta, V. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)36959-5 · Cited by 151 · see citing works

Rer1p, a Retrieval Receptor for Endoplasmic Reticulum Membrane Proteins, Is Dynamically Localized to the Golgi Apparatus by Coatomer

Sato, K., Sato, M., & Nakano, A. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.5.935 · Cited by 145 · see citing works

Post-translation Control of Nramp Metal Transport in Yeast

Liu, X. F., & Culotta, V. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.8.4863 · Cited by 145 · see citing works

Resistance to Salmonellosis in the Chicken Is Linked toNRAMP1and TNCPreprint

Hu, J., Bumstead, N., Barrow, P., Sebastiani, G., Olien, L., Morgan, K. W., & Malo, D. (1997) · Genome Research · doi:10.1101/gr.7.7.693 · Cited by 144 · see citing works

Genomic Organization and Sequence of the Human NRAMP Gene: Identification and Mapping of a Promoter Region Polymorphism

Blackwell, J. M., Barton, C. H., White, J. K., Searle, S., Baker, A.-M., Williams, H. P., & Shaw, M. (1995) · Molecular Medicine · doi:10.1007/bf03401567 · Cited by 143 · see citing works

Alternative Splicing Regulates the Subcellular Localization of Divalent Metal Transporter 1 Isoforms

Tabuchi, M., Tanaka, N., Nishida-Kitayama, J., Ohno, H., & Kishi, F. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-03-0165 · Cited by 141 · see citing works

Malvolio, the Drosophila homologue of mouse NRAMP-1 (Bcg), is expressed in macrophages and in the nervous system and is required for normal taste behaviour.

Rodrigues, V., Cheah, P. Y., Ray, K., & Chia, W. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07303.x · Cited by 136 · see citing works

Mycobacterium tuberculosis Expresses a Novel Ph-Dependent Divalent Cation Transporter Belonging to the Nramp Family

Agranoff, D. D., Monahan, I. M., Mangan, J. A., Butcher, P. D., & Krishna, S. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.5.717 · Cited by 130 · see citing works

Functional Complementation of the Yeast Divalent Cation Transporter Family SMF by NRAMP2, a Member of the Mammalian Natural Resistance-associated Macrophage Protein Family

Pinner, E., Gruenheid, S., Raymond, M., & Gros, P. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.46.28933 · Cited by 115 · see citing works

Cloning and characterization of a second human NRAMP gene on chromosome 12q13

Vidal, S. M., Belouchi, A., Cellier, M. F., Beatty, B., & Gros, P. (1995) · Mammalian Genome · doi:10.1007/bf00352405 · Cited by 114 · see citing works

Differential iron transport into phagosomes isolated from the RAW264.7 macrophage cell lines transfected with Nramp1Gly169 or Nramp1Asp169

Kuhn, D. E., Baker, B. D., Lafuse, W. P., & Zwilling, B. S. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.1.113 · Cited by 113 · see citing works

A physiological model to study iron recycling in macrophages

Delaby, C., Pilard, N., Hetet, G., Driss, F., Grandchamp, B., Beaumont, C., & Canonne-Hergaux, F. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.07.002 · Cited by 103 · see citing works

Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6

Lam-Yuk-Tseung, S., Govoni, G. R., Forbes, J., & Gros, P. (2003) · Blood · doi:10.1182/blood-2002-07-2108 · Cited by 103 · see citing works

Rer1p, a Retrieval Receptor for ER Membrane Proteins, Recognizes Transmembrane Domains in Multiple Modes

Sato, K., Sato, M., & Nakano, A. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-12-0777 · Cited by 102 · see citing works

Dynamic Traffic through the Recycling Compartment Couples the Metal Transporter Nramp2 (DMT1) with the Transferrin Receptor

Touret, N., Furuya, W., Forbes, J., Gros, P., & Grinstein, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212374200 · Cited by 101 · see citing works

The natural resistance-associated macrophage protein 1 Slc11a1 (formerly Nramp1) and iron metabolism in macrophages

Wyllie, S., Seu, P., & Goss, J. A. (2002) · Microbes and Infection · doi:10.1016/s1286-4579(02)01548-4 · Cited by 101 · see citing works

Expression and subcellular localization of NRAMP1 in human neutrophil granules

Canonne‐Hergaux, F., Calafat, J., Richer, É., Cellier, M. F., Grinstein, S., Borregaard, N., & Gros, P. (2002) · Blood · doi:10.1182/blood.v100.1.268 · Cited by 97 · see citing works

Vps26p, a Component of Retromer, Directs the Interactions of Vps35p in Endosome-to-Golgi Retrieval

Reddy, J. V., & Seaman, M. N. J. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.10.3242 · Cited by 95 · see citing works

NH2-terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain.

Barton, C. H., White, J. K., Roach, T. I. A., & Blackwell, J. M. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.5.1683 · Cited by 92 · see citing works

Association of twelve candidate gene polymorphisms and response to challenge with Salmonella enteritidis in poultry

Kramer, J., Malek, M., & Lamont, S. J. (2003) · Animal Genetics · doi:10.1046/j.1365-2052.2003.01027.x · Cited by 83 · see citing works

Iron transport into<i>Mycobacterium avium</i>-containing phagosomes from an<i>Nramp1</i><i>Gly169</i>-transfected RAW264.7 macrophage cell line

Kuhn, D. E., Lafuse, W. P., & Zwilling, B. S. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.69.1.43 · Cited by 79 · see citing works

High level expression of Nramp1G169 in RAW264.7 cell transfectants: analysis of intracellular iron transport

ATKINSON, & Barton (1999) · Immunology · doi:10.1046/j.1365-2567.1999.00672.x · Cited by 74 · see citing works

The Requirement for Yeast Superoxide Dismutase Is Bypassed through Mutations in BSD2 , a Novel Metal Homeostasis Gene

Liu, X. F., & Culotta, V. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.11.7037 · Cited by 70 · see citing works

Solute carrier 11a1 (Slc11a1; formerly Nramp1) regulates metabolism and release of iron acquired by phagocytic, but not transferrin-receptor-mediated, iron uptake

MULERO, V., SEARLE, S., BLACKWELL, J. M., & BROCK, J. H. (2002) · Biochemical Journal · doi:10.1042/bj3630089 · Cited by 70 · see citing works

Multiple Interactions Drive Adaptor-Mediated Recruitment of the Ubiquitin Ligase Rsp5 to Membrane Proteins In Vivo and In Vitro

Sullivan, J. A., Lewis, M., Nikko, E., & Pelham, H. R. B. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-01-0011 · Cited by 69 · see citing works

Slc11a1, Formerly Nramp1, Is Expressed in Dendritic Cells and Influences Major Histocompatibility Complex Class II Expression and Antigen-Presenting Cell Function

Stober, C. B., Brode, S., White, J. K., Popoff, J.-F., & Blackwell, J. M. (2007) · Infection and Immunity · doi:10.1128/iai.00153-07 · Cited by 68 · see citing works

Ectopic expression of Nramp1 in COS‐1 cells modulates iron accumulation

Atkinson, P. G. P., & Barton, C. H. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00236-1 · Cited by 67 · see citing works

Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux

Chung, J., Haile, D. J., & Wessling‐Resnick, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306622101 · Cited by 54 · see citing works

Slc11a1-mediated resistance toSalmonella entericaserovar Typhimurium andLeishmania donovaniinfections does not require functional inducible nitric oxide synthase or phagocyte oxidase activity

White, J. K., Mastroeni, P., Popoff, J.-F., Evans, C. A., & Blackwell, J. M. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0904546 · Cited by 51 · see citing works

Comparative Analysis of Two Nramp Loci from Rainbow Trout

Dorschner, M. O., & Phillips, R. B. (1999) · DNA and Cell Biology · doi:10.1089/104454999315123 · Cited by 50 · see citing works

Expression of ZRC1 Coding for Suppressor of Zinc Toxicity Is Induced by Zinc-starvation Stress in Zap1-Dependent Fashion in Saccharomyces cerevisiae

Miyabe, S., Izawa, S., & Inoue, Y. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3580 · Cited by 41 · see citing works

Stabilized expression of mRNA is associated with mycobacterial resistance controlled by Nramp1

Brown, D., Lafuse, W. P., & Zwilling, B. S. (1997) · Infection and Immunity · doi:10.1128/iai.65.2.597-603.1997 · Cited by 38 · see citing works

Genetic and physical mapping of the natural resistance-associated macrophage protein 1 (NRAMP1) in chicken

Hu, J. G., Bumstead, N., Burke, D., de León, F. A. P., Skamene, E., Gros, P., & Malo, D. (1995) · Mammalian Genome · doi:10.1007/bf00539010 · Cited by 36 · see citing works

Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes.

Lam-Yuk-Tseung, S., Touret, N., Grinstein, S., & Gros, P. (2005) · Biochemistry · doi:10.1021/bi050911r · Cited by 35 · see citing works

Structural Organization, Sequence, and Expression of the Chicken NRAMP1 Gene Encoding the Natural Resistance-Associated Macrophage Protein 1

Hu, J., Bumstead, N., Skamene, E., Gros, P., & Malo, D. (1996) · DNA and Cell Biology · doi:10.1089/dna.1996.15.113 · Cited by 34 · see citing works

Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1)

White, J. K., Stewart, A., Popoff, J.-F., Wilson, S., & Blackwell, J. M. (2004) · Biochemical Journal · doi:10.1042/bj20040808 · Cited by 29 · see citing works

Intestinal over-expression of iron transporters induces iron overload in birds in captivity

Mete, A., Jalving, R., van Oost, B. A., van Dijk, J. E., & Marx, J. J. M. (2005) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2004.12.001 · Cited by 29 · see citing works

Phenotypic difference between Bcgr and Bcgs macrophages is related to differences in protein‐kinase‐C‐dependent signalling

Olivier, M., Cook, P., Sanctis, J. B. D., Hel, Z., Wojciechowski, W., Reiner, N. E., Skamene, E., & Radzioch, D. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2510734.x · Cited by 25 · see citing works

Functional analysis of the human NRAMP family expressed in fission yeast

Tabuchi, M., Yoshida, T., Takegawa, K., & Kishi, F. (1999) · Biochemical Journal · doi:10.1042/bj3440211 · Cited by 25 · see citing works

Regulation of Nramp1 mRNA stability by oxidants and protein kinase C in RAW264.7 macrophages expressing Nramp1Gly169

Lafuse, W. P., Alvarez, G. R., & Zwilling, B. S. (2000) · Biochemical Journal · doi:10.1042/bj3510687 · Cited by 24 · see citing works

Comparative Analysis of Two slc11 ( Nramp ) Loci in Takifugu rubripes

Sibthorpe, D., Baker, A.-M., Gilmartin, B. J., Blackwell, J. M., & White, J. K. (2004) · DNA and Cell Biology · doi:10.1089/104454904322745925 · Cited by 16 · see citing works

Role of MAP kinase activation in Nramp1 mRNA stability in RAW264.7 macrophages expressing Nramp1(Gly169).

Lafuse, W., Álvarez, G. R., & Zwilling, B. (2002) · Cellular Immunology · doi:10.1016/s0008-8749(02)00026-6 · Cited by 11 · see citing works

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

Seaman, M. N. J., Harbour, M. E., Tattersall, D., Read, E. K. C., & Bright, N. A. (2009) · Journal of Cell Science · doi:10.1242/jcs.048686 · Cited by 367 · see citing works

Macrophages and Systemic Iron Homeostasis

Ganz, T. (2012) · Journal of Innate Immunity · doi:10.1159/000336423 · Cited by 281 · see citing works

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels

Nairz, M., Theurl, I., Swirski, F. K., & Weiss, G. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1944-8 · Cited by 178 · see citing works

Mammalian iron transporters: Families SLC11 and SLC40

Montalbetti, N., Simonin, A., Kovács, G., & Hediger, M. A. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2013.01.002 · Cited by 147 · see citing works

Nramp1 and Other Transporters Involved in Metal Withholding during Infection

Wessling-Resnick, M. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.r115.643973 · Cited by 136 · see citing works

Bacterial metal-sensing proteins exemplified by ArsR–SmtB family repressors

Osman, D., & Cavet, J. S. (2010) · Natural Product Reports · doi:10.1039/b906682a · Cited by 124 · see citing works

Genetics and visceral leishmaniasis: of mice and man

Blackwell, J. M., Fakiola, M., Ibrahim, M. E., Jamieson, S. E., Jerônimo, S. M. B., Miller, E. N., Mishra, A., Mohamed, H. S., Peacock, C. S., RAJU, M., et al. (2009) · Parasite Immunology · doi:10.1111/j.1365-3024.2009.01102.x · Cited by 113 · see citing works

Molecular Mechanism of Nramp-Family Transition Metal Transport

Bozzi, A. T., & Gaudet, R. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.166991 · Cited by 114 · see citing works

Macrophages and Iron Metabolism

Ganz, T. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.mchd-0037-2016 · Cited by 108 · see citing works

The phage shock protein PspA facilitates divalent metal transport and is required for virulence of <i>Salmonella enterica</i> sv. Typhimurium

Karlinsey, J. E., Maguire, M. E., Becker, L. A., Crouch, M. V., & Fang, F. C. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07357.x · Cited by 102 · see citing works

Intracellular Distribution of Manganese by the Trans-Golgi Network Transporter NRAMP2 Is Critical for Photosynthesis and Cellular Redox Homeostasis

Alejandro, S., Cailliatte, R., Alcon, C., Dirick, L., Domergue, F., Correia, D., Castaings, L., Briat, J., Mari, S., & Curie, C. (2017) · The Plant Cell · doi:10.1105/tpc.17.00578 · Cited by 105 · see citing works

SMF-1, SMF-2 and SMF-3 DMT1 Orthologues Regulate and Are Regulated Differentially by Manganese Levels in C. elegans

Au, C., Benedetto, A., Anderson, J. G., Labrousse, A. M., Erikson, K. M., Ewbank, J. J., & Aschner, M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007792 · Cited by 103 · see citing works

Cellular iron transport

Garrick, M. D., & Garrick, L. M. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.03.018 · Cited by 102 · see citing works

H+-Coupled Divalent Metal-Ion Transporter-1

Shawki, A., Knight, P. B., Maliken, B. D., Niespodzany, E. J., & Mackenzie, B. (2012) · Current topics in membranes · doi:10.1016/b978-0-12-394316-3.00005-3 · Cited by 94 · see citing works

The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome

Van Zandt, K. E., Sow, F. B., Florence, W. C., Zwilling, B. S., Satoskar, A. R., Schlesinger, L. S., & Lafuse, W. P. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.1107781 · Cited by 74 · see citing works

Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis

Foulquier, F., & Legrand, D. (2020) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2020.129674 · Cited by 48 · see citing works

Metal Sensing in Salmonella

Osman, D., & Cavet, J. S. (2011) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/b978-0-12-381043-4.00005-2 · Cited by 41 · see citing works

Malvolio is a copper transporter inDrosophila melanogaster

Southon, A. G., Farlow, A., Norgate, M., Burke, R., & Camakaris, J. (2008) · Journal of Experimental Biology · doi:10.1242/jeb.014159 · Cited by 40 · see citing works

Sudden Sensorineural Hearing Loss and Polymorphisms in Iron Homeostasis Genes: New Insights from a Case-Control Study

Castiglione, A., Ciorba, A., Aimoni, C., Orioli, E., Zeri, G., Vigliano, M., & Gemmati, D. (2015) · BioMed Research International · doi:10.1155/2015/834736 · Cited by 33 · see citing works

Intracellular microbes and haemophagocytosis

Silva‐Herzog, E., & Detweiler, C. S. (2008) · Cellular Microbiology · doi:10.1111/j.1462-5822.2008.01192.x · Cited by 32 · see citing works

Dictyostelium Nramp1, structurally and functionally close to mammalian DMT1 transporter, mediates phagosomal iron efflux

Buracco, S., Peracino, B., Cinquetti, R., Signoretto, E., Vollero, A., Imperiali, F. G., Castagna, M., Bossi, E., & Bozzaro, S. (2015) · Journal of Cell Science · doi:10.1242/jcs.173153 · Cited by 31 · see citing works

Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function

García‐Rodríguez, N., Manzano‐Lopez, J., Muñoz-Bravo, M., Fernández‐García, E., Muñiz, M., & Wellinger, R. E. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.616334 · Cited by 27 · see citing works

Natural history of SLC11 genes in vertebrates: tales from the fish world

Neves, J. V., Wilson, J. M., Kuhl, H., Reinhardt, R., Castro, L. F. C., & Rodrigues, P. N. (2011) · BMC Evolutionary Biology · doi:10.1186/1471-2148-11-106 · Cited by 24 · see citing works

Structural basis for metal ion transport by the human SLC11 proteins DMT1 and NRAMP1

Liziczai, M., Fuchs, A., Manatschal, C., & Dutzler, R. (2025) · Nature Communications · doi:10.1038/s41467-024-54705-0 · Cited by 22 · see citing works

Transport proteins promoting Escherichia coli pathogenesis

Tang, F., & Saier, M. H. (2014) · Microbial Pathogenesis · doi:10.1016/j.micpath.2014.03.008 · Cited by 22 · see citing works

The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition

Wu, K.-C., Liou, H., Kao, Y.-H., Lee, C.-Y., & Lin, C. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2017.05.001 · Cited by 18 · see citing works

Elucidation of the Functional Metal Binding Profile of a CdII/PbII Sensor CmtRSc from Streptomyces coelicolor

Wang, Y., Kendall, J. J., Cavet, J. S., & Giedroc, D. P. (2010) · Biochemistry · doi:10.1021/bi100490u · Cited by 18 · see citing works

Iron

Bury, N. R., Boyle, D., & Cooper, C. A. (2011) · Fish physiology · doi:10.1016/s1546-5098(11)31004-7 · Cited by 18 · see citing works

Duplication and Sub/Neofunctionalization of Malvolio , an Insect Homolog of Nramp , in the Subsocial Beetle Nicrophorus vespilloides

Mehlferber, E. C., Benowitz, K. M., Roy-Zokan, E. M., McKinney, E. C., Cunningham, C. B., & Moore, A. J. (2017) · G3 Genes Genomes Genetics · doi:10.1534/g3.117.300183 · Cited by 16 · see citing works

Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population

Rye, M. S., Wiertsema, S. P., Scaman, E. S. H., Thornton, R. B., Francis, R. W., Vijayasekaran, S., Coates, H. L. C., Jamieson, S. E., & Blackwell, J. M. (2013) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2013.03.023 · Cited by 9 · see citing works

Macrophages and Iron Metabolism

Ganz, T. (2017) · ASM Press eBooks · doi:10.1128/9781555819194.ch46 · Cited by 10 · see citing works

Positive selection in the SLC11A1 gene in the family Equidae

Bayerová, Z., Jánová, E., Matiašovic, J., Orlando, L., & Hořín, P. (2016) · Immunogenetics · doi:10.1007/s00251-016-0905-2 · Cited by 8 · see citing works

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Qiu, L., Zhang, Y., Tang, Y., Hu, H., Zhang, Y., Xue, J., Wang, H., Wang, Y., Liu, C., Jia, J., et al. (2026) · Advanced Science · doi:10.1002/advs.202511482 · Cited by 5 · see citing works

Structural characterization and molecular dynamics simulations of the caprine and bovine solute carrier family 11 A1 (SLC11A1)

Triantaphyllopoulos, K. A., Baltoumas, F. A., & Hamodrakas, S. J. (2018) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-018-0179-x · Cited by 5 · see citing works

Association between rheumatoid arthritis and genetic variants of natural resistance‐associated macrophage protein 1 gene: A meta‐analysis

Wang, H., Yuan, F., Dai, Z., Wang, B., & Dong-qing, Y. (2018) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.13366 · Cited by 5 · see citing works

A Comprehensive Review of Membrane Transporters and MicroRNA Regulation in Alzheimer’s Disease

Mishra, S., Stany, B. K., Das, A., Deepankumar, K., & Vijayan, M. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04135-2 · Cited by 5 · see citing works

Heterologous (Over) Expression of Human SoLute Carrier (SLC) in Yeast: A Well-Recognized Tool for Human Transporter Function/Structure Studies

Pochini, L., & Galluccio, M. (2022) · Life · doi:10.3390/life12081206 · Cited by 3 · see citing works

CHLOROPLAST STRUCTURAL AND FUNCTIONAL CHANGES AS BIOMARKERS OF HEAVY METAL CONTAMINATION

Vodka, M. V. (2016) · Biotechnologia Acta · doi:10.15407/biotech9.01.103 · Cited by 2 · see citing works

Immunogenetics of Host Response to Parasites in Humans

Blackwell, J. M. (2014) · ASM Press eBooks · doi:10.1128/9781555816872.ch38 · Cited by 1 · see citing works

Survival of different Mycobacterium avium subsp. paratuberculosis strains in bovine monocyte-derived macrophages

Klee, W., & Schukken, Y. H. (2008)

Transport proteins promoting E. coli pathogenesis

Tang, F. (2013) · eScholarship (California Digital Library)

Iron and Immunity

Crichton, R. R. (2016) · Wiley eBooks · doi:10.1002/9781118925645.ch12

Functional Complementation of the Yeast Divalent Cation Transporter Family SMF by NRAMP2, a Member of the Mammalian Natural Resistance-associated Macrophage Protein Family

Pinner, E., Gruenheid, S., Raymond, M., & Gros, P. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.46.28933 · Cited by 115 · see citing works

Determination of the transmembrane topology of mammalian SLC11A2 by an epitope mapping approach

Czachorowski, M. (2009) · eScholarship@McGill (McGill) · doi:10.82308/16036

Slc11 Synapomorphy: A Conserved 3D Framework Articulating Carrier Conformation Switch

Cellier, M. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015076 · Cited by 4 · see citing works

Human SLC4A11 does not complement BOR1 or support borate transport in Saccharomyces cerevisiae

Beltran, J. L., Bain, R. K., Stiefel, M. J., McDonnell, A. S., Carr, N. N., & Thurtle-Schmidt, B. H. (2022) · PubMed Central · doi:10.17912/micropub.biology.000605 · Cited by 5 · see citing works

Natural history of SLC11 genes in vertebrates: tales from the fish world

Neves, J. V., Wilson, J. M., Kuhl, H., Reinhardt, R., Castro, L. F. C., & Rodrigues, P. N. (2011) · BMC Evolutionary Biology · doi:10.1186/1471-2148-11-106 · Cited by 24 · see citing works