Effects of diagnostic comorbidity and dimensional symptoms of attention-deficit-hyperactivity disorder in men with antisocial personality disorder
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Objective: Although children with attention deficit hyperactivity disorder (ADHD) are at increased risk for later onset of antisocial personality disorder (APD) as adults, the utility of ADHD as either a comorbid diagnosis (ADHD c ) or dimensional symptoms (ADHD d ) in predicting behaviour and substance use problems in APD subjects has not been examined. Method: A total of 105 adult male offenders with Structured Clinical Interview for Axis II Disorders (SCID-II)-based DSM-III-R APD were studied in terms of: (i) psychopathy scores on the Hare Psychopathy Checklist–Revised (PCL-R); (ii) ADHD c diagnostic comorbidity on clinically administered DSM-IV questionnaire; and (iii) ADHD d dimensional symptoms by means of Wender Utah Rating Scale (WURS) and Conners Adult ADHD Rating Scale (CAARS) during a 12 month study period (May 2005–May 2006). Results: Sixty five per cent of APD subjects met criteria for ADHD c diagnostic comorbidity with significantly increased rates of childhood neglect, parental divorce and suicide attempt, but not of psychopathy. APD subjects with ADHD d symptoms were noted to have earlier onset and increased rate of self-injurious behaviour (SIB), suicide attempt, and psychopathy. The psychopathy scores, in turn, were predictive of earlier onset of SIB and behavioural problems. Conclusion: Both ADHD c diagnostic comorbidity and ADHD d symptoms need to be assessed in APD subjects and the dimensional measures may be better in detecting earlier onset SIB, suicide attempt and other behavioural problems.
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The comorbidity between ADHD and the different emotional instability disorders is remarkably large.
“The comorbidity between ADHD and the different emotional instability disorders is remarkably large.”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Semiz et al., 2008
The Results (page not available) report that 68 of 105 men with antisocial personality disorder (65%) also met ADHD criteria, supporting substantial comorbidity for that disorder. The paper lists other personality disorders in the sample but does not establish similarly large ADHD comorbidity across different emotional instability disorders. (LLM, conf=0.82)
Experimental — accuracy not yet measuredEmotional instability disorders (BPD, ASPD, CD) have a high rate of comorbidity with ADHD and ADHD symptoms.
“Although all these disorders have a high rate of comorbidity with ADHD and with ADHD symptoms, they are unquestionably different from classical DSM-5 ADHD.”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Semiz et al., 2008
The Results report that 65% of the men with antisocial personality disorder (APD) met ADHD diagnostic criteria, and the Conclusion describes a strong association among ADHD, childhood conduct disorder and APD. The paper also examines ADHD symptoms in APD. It does not establish a high rate of ADHD comorbidity or symptoms in borderline personality disorder (BPD); the Results mention BPD only as another diagnosis in some APD subjects. (LLM, conf=0.86)
Experimental — accuracy not yet measuredUp to 65% of men with ASPD were reported to present comorbid ADHD.
“Up to 65% of men with ASPD were reported to present comorbid ADHD (Semiz et al., 2008).”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Semiz et al., 2008
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- Authors
- Semiz, U. B., Basoglu, C., Oner, O., Munir, K. M., Ates, A., Algul, A., Ebrinc, S., & Cetin, M.
- Affiliations
- Department of Psychiatry, GATA Haydarpasa Training Hospital, Istanbul, 34668, Turkey
- Department of Child and Adolescent Psychiatry, Diskapi State Hospital, Ankara, Turkey
- Department of Psychiatry, Children's Hospital, Harvard Medical School, Boston, MA, USA
- GATA Haydarpaşa Eğitim Hastanesi (TR)
- ORCID
- Ates, Alpay
- Venue
- Australian & New Zealand Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2008-01-01
- Volume
- 42
- Issue
- 5
- Pages
- 405-413
- ISSN
- 0004-8674 (ISSN-L)
- 1440-1614
- PMC
- PMC3166642
- OpenAlex
- W2134642433
- Cited by
- 58
- References
- 41
- Citations by year
- 2025: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 2 · 2018: 5 · 2017: 4 · 2016: 4 · 2015: 1 · 2014: 9 · 2013: 2 · 2012: 7
- FWCI
- 6.32
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Australian & New Zealand Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Fogarty International Center (D43TW005807)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- attention deficit hyperactivity disorder, antisocial personality disorder, comorbidities, psychopathy, self-harm, suicide attempts, adult male offenders, child neglect, parental divorce, problematic substance use, behavioral problems
- MeSH terms
- Adult, Antisocial Personality Disorder, Attention Deficit Disorder with Hyperactivity, Child, Child Abuse, Crime, Divorce, Humans, Male, Military Personnel, Parents, Predictive Value of Tests, Prisoners, Psychiatric Status Rating Scales, Suicide, Attempted, Turkey, Comorbidity, Self-Injurious Behavior, Age of Onset
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