The DOI matches its Crossref record; 86 of the 86 references it cites were found in a registry or an index.
Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases
Open accessAbstract
Periodontal diseases, such as chronic periodontitis, share common inflammatory risk factors with other systemic and chronic inflammatory disorders. Mucosal tissues, such as oral epithelia, are exposed to environmental stressors, such as tobacco and oral bacteria, that might be involved in promoting a systemic inflammatory state. Conversely, chronic disorders can also affect oral health. This review will summarize recent evidence for the interrelationship between chronic periodontitis and other prevalent chronic diseases such as cardiovascular diseases, diabetes, cancer and chronic respiratory diseases. The association with pregnancy is also included due to possible obstetric complications. We will focus on inflammatory cytokines such as TNF-alpha, IL-1, and IL-6, because they have been shown to be increased in patients with chronic periodontitis, in patients with chronic systemic diseases, and in patients with both chronic periodontitis and other chronic diseases. Therefore, an imbalance towards a proinflammatory immune response could underline a bidirectional link between chronic periodontitis and other chronic diseases. Finally, we highlight that a close coordination between dental and other health professionals could promote oral health and prevent or ameliorate other chronic diseases.
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Citations
Cites
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Cited by
Periodontal Inflammation and Systemic Diseases: An Overview
Martínez-García, M., & Hernández-Lemus, E. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.709438 · Cited by 512
Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review
Cheng, R., Wu, Z., Li, M., Shao, M., & Hu, T. (2020) · International Journal of Oral Science · doi:10.1038/s41368-019-0068-8 · Cited by 298
Li, Y., Yang, L., Hou, Y., Zhang, Z., Chen, M., Wang, M., Liu, J., Wang, J., Zhao, Z., Xie, C., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.03.021 · Cited by 280
Do Changes in Oral Microbiota Correlate With Plasma Nitrite Response? A Systematic Review
Zhurakivska, K., Troiano, G., Caponio, V. C. A., Dioguardi, M., Laino, L., Maffione, A. B., & Lo Muzio, L. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01029 · Cited by 37
Balci, N., Cekici, A., Kurgan, Ş., Sahinkaya, S., & Serdar, M. A. (2021) · Journal of Periodontal Research · doi:10.1111/jre.12859 · Cited by 27
Metadata
- Authors
- Cardoso, E. M., Reis, C., & Manzanares-Céspedes, M. C.
- Venue
- Postgraduate Medicine
- Publisher
- Informa UK Limited
- Published
- 2017-11-08
- Volume
- 130
- Issue
- 1
- Pages
- 98-104
- ISSN
- 0032-5481 (ISSN-L)
- 1941-9260
- OpenAlex
- W2766925184
- Cited by
- 484
- References
- 86
- FWCI
- 31.20
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Cardoso, E. M., Reis, C., & Manzanares-Céspedes, M. C. (2018). Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases. Postgraduate Medicine. https://doi.org/10.1080/00325481.2018.1396876
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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